Omega 3 Fatty Acid Supplementation For 12 Weeks Increases Resting And Exercise Metabolic Rate In Healthy Community Dwelling Older Females(1)

This study examined whether fish oil supplements could help combat age-related metabolic decline in older women. As we age, our metabolism naturally slows down, we lose muscle mass, and gain fat - changes that can increase disease risk and reduce quality of life. Researchers wanted to see if omega-3 fatty acids from fish oil could help reverse these trends.

Twenty-four healthy women around age 66 participated in this 12-week study. Half received 3 grams daily of EPA and DHA (the active omega-3s found in fish oil), while the other half took olive oil as a placebo. The researchers measured their resting metabolic rate, energy expenditure during exercise, body composition, strength, and various blood markers before and after supplementation.

The results were striking. Women taking fish oil experienced a 14% increase in resting metabolic rate - meaning they burned more calories even while at rest. During exercise, they burned 10% more energy overall and increased fat burning by 19% at rest and 27% during exercise. Additionally, they gained 4% more lean muscle mass, improved physical function by 7%, and reduced triglyceride levels by 29%. The placebo group showed no significant changes.

These findings suggest that omega-3 supplementation might be a valuable tool for maintaining metabolic health as we age. In clinical practice, this research supports discussing fish oil supplementation with patients concerned about age-related metabolic changes, particularly older women looking to maintain muscle mass and metabolic function as part of their longevity strategy.