Metabolic
Library
1,810 peer-reviewed papers, each with a plain-language summary and the source document. The evidence behind the VALIA method, kept where you can read it.
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1,810 papers
· 13 topics
Brain and Nerve Health results
101 results in Brain and Nerve Health · page 1 of 3
- Brain and Nerve Health
1,25 Dihydroxyvitamin D3 Reversibly Blocks The Progression Of Relapsing Encephalomyelitis, A Model Of Multiple Sclerosis
Researchers found that the active form of vitamin D can prevent and halt progression of a mouse model of multiple sclerosis, while vitamin D deficiency increases disease risk.
- Brain and Nerve Health
2 Deoxyglucose And Beta Hydroxybutyrate Metabolic Agents For Seizure Control
Researchers are studying two natural compounds - 2-deoxyglucose and beta-hydroxybutyrate - as potential "diet in a pill" alternatives to help control seizures through metabolic changes rather than traditional medications.
- Brain and Nerve Health
A Ketogenic Diet Reduces Amyloid Beta 40 And 42 In A Mouse Model Of Alzheimer S Disease
A ketogenic diet (very low carbs, high fat) reduced harmful brain proteins linked to Alzheimer's disease by 25% in mice genetically prone to the condition.
- Brain and Nerve Health
A Ketogenic Diet Suppresses Seizures In Mice Through Adenosine A1 Receptors
Researchers discovered that ketogenic diets reduce seizures in mice by boosting a brain chemical called adenosine, which has a natural calming effect on brain cells.
- Brain and Nerve Health
A New Way To Produce Hyperketonemia Use Of Ketone Ester In A Case Of Alzheimer’s
Researchers tested a ketone ester drink as an alternative brain fuel for Alzheimer's patients, since their brains struggle to use glucose effectively.
- Brain and Nerve Health
A Non Invasive Determination Of Ketosis Induced Elimination Of Chronic Daytime Somnolence In A Patient
A ketogenic diet successfully eliminated chronic daytime sleepiness in a dementia patient by putting the body into ketosis, suggesting the brain may have repaired itself.
- Brain and Nerve Health
A Non Invasive Determination Of Ketosis Induced Elimination Of Chronic Daytime Somnolence In A Patient With Late Stage Dementia (Assessed With Type 3 Diabetes) A Potential Role Of Neurogenesis
Researchers found that a ketogenic diet and ketone supplements helped eliminate excessive daytime sleepiness in an elderly woman with late-stage dementia, possibly by promoting brain cell repair.
- Brain and Nerve Health
An Anti Inflammatory Approach To The Dietary Management Of Multiple Sclerosis A Condensed Review
This review examines how anti-inflammatory diets may help manage multiple sclerosis by reducing inflammation that damages the nervous system.
- Brain and Nerve Health
An Experimental Ketogenic Diet For Alzheimer Disea
Researchers found that people with Alzheimer's disease could successfully follow a nutritionally dense ketogenic diet rich in vegetables and avocado for three months.
- Brain and Nerve Health
An Experimental Ketogenic Diet For Alzheimer Disease Was Nutritionally Dense And Rich In Vegetables And Avocado
Researchers found that people with Alzheimer's disease could successfully follow a ketogenic diet rich in vegetables and avocado while maintaining good nutrition.
- Brain and Nerve Health
Anti Oxidant And Anti Inflammatory Activity Of Ketogenic Diet New Perspectives For Neuroprotection In Alzheimer’s Disease
Research suggests the ketogenic diet may protect brain cells from damage in Alzheimer's disease by reducing harmful inflammation and cellular stress.
- Brain and Nerve Health
ApoE4 Impairs Neuron Astrocyte Coupling Of Fatty Acid Metabolism
People with the ApoE4 gene variant have disrupted fat processing between brain cells, which may contribute to increased Alzheimer's disease risk.
- Brain and Nerve Health
Association Between Consumption Of Ultraprocessed Foods And Cognitive Decline
A large Brazilian study found that people who ate more ultraprocessed foods experienced faster cognitive decline and memory problems over 8 years of follow-up.
- Brain and Nerve Health
Astrocyte Metabolism And Signaling Pathways In The CNS
Astrocytes, brain cells that make up half of our central nervous system, play a crucial role in brain metabolism and their dysfunction may contribute to neurological diseases like depression and Alzheimer's.
- Brain and Nerve Health
Autism Reversal Case Study
Researchers documented how two twin toddlers with severe autism showed significant improvement through personalized lifestyle and environmental changes targeting their specific symptoms.
- Brain and Nerve Health
Can Ketogenic Diet Therapy Improve Migraine Frequency, Severity And Duration
A small study found that a ketogenic diet may help reduce migraine frequency and severity compared to a standard anti-headache diet, though side effects were common.
- Brain and Nerve Health
Can Ketones Compensate For Deteriorating Brain Glucose Uptake During Aging Implications For The Risk And Treatment Of Alzheimer’s Disease
Researchers found that ketones (an alternative brain fuel) may help compensate for the brain's declining ability to use glucose in Alzheimer's disease and aging.
- Brain and Nerve Health
Can Ketones Help Rescue Brain Fuel Supply In Later Life Implications For Cognitive Health During Aging And The Treatment Of Alzheimer’s Disease
Research suggests that ketones (molecules produced during fasting or low-carb diets) may help protect brain function in aging and Alzheimer's disease by providing alternative fuel when glucose uptake declines.
- Brain and Nerve Health
Can The Ketogenic Diet Lead To Wernicke’s Encephalopathy
A case report describes a 16-year-old who developed a serious brain condition called Wernicke's encephalopathy after rapid weight loss on a ketogenic diet due to thiamine (vitamin B1) deficiency.
- Brain and Nerve Health
Ceramides Mediate Insulin Induced Impairments In Cerebral Mitochondrial Bioenergetics In ApoE4 Mice
Researchers found that high insulin levels damage brain cell energy production in Alzheimer's disease mice by increasing harmful fat molecules called ceramides.
- Brain and Nerve Health
Cognitive Demand And Dementia
Researchers propose that lack of mental challenge may be the primary cause of dementia, suggesting our brains need regular cognitive "exercise" to stay healthy, similar to how muscles need physical exercise.
- Brain and Nerve Health
Cognitive Function And Vitamin B12 And D Among Community Dwelling Elders
A study of over 1,700 older adults found that low vitamin B12 levels were linked to worse cognitive function, especially after age 75, while vitamin D levels showed no connection.
- Brain and Nerve Health
Could Alzheimer’s Disease Be A Maladaptation Of An Evolutionary Survival Pathway Mediated By Intracerebral Fructose And Uric Acid Metabolism
Researchers propose that Alzheimer's disease may result from an ancient survival mechanism triggered by fructose and sugar that becomes harmful when constantly activated by modern high-sugar diets.
- Brain and Nerve Health
Diet Transiently Improves Migraine In Twin Sisters
Twin sisters with frequent migraines found their headaches temporarily disappeared when they followed a ketogenic diet for weight loss.
- Brain and Nerve Health
Dietary Intake Of Plant Sterols Stably Increases Plant Sterol Levels In The Murine Brain
This mouse study found that plant sterols from cholesterol-lowering supplements can accumulate in the brain and remain there long-term, even after stopping the supplements.
- Brain and Nerve Health
Du Et Al 2025 High And Low Fat Dairy Consumption And Long Term Risk Of Dementia
A 25-year study of nearly 28,000 people found that eating high-fat dairy products like cheese and cream was linked to lower dementia risk.
- Brain and Nerve Health
Effects Of Acetyl L Carnitine On Oxidative Stress In Amyotrophic Lateral Sclerosis Patients Evaluation On Plasma Markers And Members Of The Neurovascular Unit
Researchers found that acetyl-L-carnitine supplements helped reduce harmful oxidative stress in ALS patients over six months of treatment.
- Brain and Nerve Health
Effects Of Classic Ketogenic Diet In Children With Refractory Epilepsy A Retrospective Cohort Study In Kingdom Of Bahrain
A ketogenic diet helped reduce seizures by more than 50% in most children with hard-to-treat epilepsy, with one-third becoming completely seizure-free.
- Brain and Nerve Health
Effects Of Ketone Bodies On Brain Metabolism And Function In Neurodegenerative Diseases
Research shows that ketone bodies (produced during fasting or ketogenic diets) can serve as alternative brain fuel and may help protect against neurodegenerative diseases like Alzheimer's and Parkinson's.
- Brain and Nerve Health
Efficacy And Safety Of Exogenous Ketone Bodies For Preventive Treatment Of Migraine A Study Protocol For A Single Centred, Randomised, Placebo Controlled, Double Blind Crossover Trial
Researchers are testing whether ketone supplements can safely prevent migraines by addressing energy problems in the brain that may trigger these headaches.
- Brain and Nerve Health
Efficacy Of Ketogenic Diet For Infantile Spasms In Chinese Patients With Or Without Monogenic Etiology(1)
A ketogenic diet helped reduce seizures in nearly half of Chinese infants with infantile spasms, with especially strong results in babies with specific genetic mutations.
- Brain and Nerve Health
Electroconvulsive Therapy Does Not Increase The Risk Of Dementia In Patients With Affective Disorders
A large Danish study found that electroconvulsive therapy (ECT) for depression does not increase the risk of developing dementia later in life.
- Brain and Nerve Health
Feasibility And Safety Of A Combined Metabolic Strategy In Glioblastoma Multiforme
Researchers found that brain cancer patients could safely follow a combined approach of periodic 5-7 day fasts and a ketogenic diet for several months.
- Brain and Nerve Health
Feasibility Of An MI CBT Ketogenic Adherence Program For Older Adults With Mild Cognitive Impairment
A small study found that older adults with mild memory problems who followed a ketogenic diet for 6 weeks showed improved thinking test scores.
- Brain and Nerve Health
Fibromyalgia Syndrome Improved Using A Mostly Raw Vegetarian Diet An Observational Study
A study found that eating a mostly raw vegetarian diet significantly reduced fibromyalgia symptoms including pain, fatigue, and depression in most participants.
- Brain and Nerve Health
Glucose Hypometabolism Is Highly Localized, But Lower Cortical Thickness And Brain Atrophy Are Widespread In Cognitively Normal Older Adults
Researchers found that healthy older adults show specific brain areas using less glucose for energy, while brain thinning occurs more widely throughout the brain.
- Brain and Nerve Health
High Low Density Lipoprotein Cholesterol Inversely Relates To Dementia In Community Dwelling Older Adults The Shanghai Aging Study
A study of nearly 4,000 older Chinese adults found that higher levels of "bad" LDL cholesterol were actually associated with lower rates of dementia.
- Brain and Nerve Health
Higher Ketogenic Diet Ratios Confer Protection From Seizures Without Neurotoxicity
Researchers found that higher-fat ketogenic diets (6:1 ratio) provided better seizure protection than standard ketogenic diets (4:1 ratio) without causing brain damage.
- Brain and Nerve Health
Higher Non Processed Red Meat Consumption Is Associated With A Reduced Risk Of Central Nervous System Demyelination
A large Australian study found that people who ate more unprocessed red meat (like steak and ground beef) had a lower risk of developing multiple sclerosis-like brain conditions.
- Brain and Nerve Health
Hypometabolism, Alzheimer’s Disease, And Possible Therapeutic Targets An Overview (1)
Research shows that reduced brain energy metabolism may actually cause Alzheimer's disease rather than just being a result of it, suggesting new treatment approaches.
- Brain and Nerve Health
Inflammation But Not Glycemic Control Is Associated With Neurocognitive Decline After Cardiac Surgery
After heart surgery, inflammation markers predicted cognitive decline better than blood sugar control, suggesting inflammation may be more important for protecting brain function.
- Brain and Nerve Health
Influence Of Dietary Patterns In The Pathophysiology Of Huntington S Disease A Literature Review
Researchers reviewed how different eating patterns like Mediterranean, ketogenic, and plant-based diets might help slow the progression of Huntington's disease, a rare brain disorder.
- Brain and Nerve Health
Islamic Fasting And Multiple Sclerosis
Research suggests that Ramadan fasting may be safe for most stable multiple sclerosis patients, though symptoms like fatigue may temporarily worsen during fasting periods.
- Brain and Nerve Health
Ketogenic And Modified Mediterranean Diet As A Tool To Counteract Neuroinflammation In Multiple Sclerosis Nutritional Suggestions
Researchers reviewed how ketogenic and modified Mediterranean diets might help reduce brain inflammation in multiple sclerosis patients by improving cognitive function and brain health markers.
- Brain and Nerve Health
Ketogenic Diet
The ketogenic diet, originally developed in 1921 to mimic fasting, can effectively control seizures in about one-third of epilepsy patients who don't respond to medications.
- Brain and Nerve Health
Ketogenic Diet And Epilepsy What We Know So Far
The ketogenic diet, a high-fat, low-carb eating plan used since the 1920s, can effectively reduce seizures in people with epilepsy that doesn't respond to medications.
- Brain and Nerve Health
Ketogenic Diet And Physical Exercise On Managing Tarlov Cysts A Case Report
A woman with painful Tarlov cysts (fluid-filled sacs on nerve roots) experienced significant pain relief and improved quality of life while following a low-calorie ketogenic diet for three months.
- Brain and Nerve Health
Ketogenic Diet For Epilepsy Treatment
The ketogenic diet, which is high in fat and very low in carbohydrates, can effectively reduce seizures in children and adults with epilepsy that doesn't respond to medications.
Disclaimer: this library, including every summary, is for general informational and educational purposes only. It does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before changing your diet, exercise, or health regimen, or if you have questions about a medical condition.