Metabolic
Library
1,810 peer-reviewed papers, each with a plain-language summary and the source document. The evidence behind the VALIA method, kept where you can read it.
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1,810 papers
· 13 topics
Evolutionary Health and Aging results
118 results in Evolutionary Health and Aging · page 1 of 3
- Evolutionary Health and Aging
“The Red Lady Of El Mirón”. Lower Magdalenian Life And Death In Oldest Dryas1 Cantabrian Spain An Overview
Scientists studied the 18,700-year-old burial of a healthy woman in Spain to understand how ancient hunter-gatherers lived, ate, and survived in harsh Ice Age conditions.
- Evolutionary Health and Aging
3.3 Million Years Of Stone Tool Complexity Suggests That Cumulative Culture Began During The Middle Pleistocene
Researchers found that human ancestors' stone tools remained simple for millions of years, then suddenly became complex around 600,000 years ago, marking when humans began building knowledge across generations.
- Evolutionary Health and Aging
A Bioenergetic Approach Favors The Preservation And Protection Of Prey, Not Cooking, As The Drivers Of Early Fire
New research suggests early humans first used fire to preserve meat and protect themselves from predators, not for cooking food.
- Evolutionary Health and Aging
A Limited Protein High Fat Diet May Explain The Low δ66Zn Conundrum In The Neandertal From Gabasa
Researchers found that Neanderthals likely ate a high-fat, moderate-protein diet similar to modern ketogenic diets, which may offer insights into human metabolic adaptation.
- Evolutionary Health and Aging
A Neandertal Dietary Conundrum Insights Provided By Tooth Enamel Zn Isotopes From Gabasa, Spain
Scientists analyzed ancient Neanderthal teeth and found evidence that our extinct human relatives were dedicated meat-eaters with unusually high levels of certain chemical markers.
- Evolutionary Health and Aging
A Paleogenomic Reconstruction Of The Deep Populati
Scientists studied ancient DNA from 89 people over 9,000 years to map how populations moved and mixed in the Andes mountains, revealing patterns of genetic stability and migration.
- Evolutionary Health and Aging
A Role For Suppressed Incisor Cuspal Morphogenesis In The Evolution Of Mammalian Heterodont Dentition
Scientists discovered how mammalian teeth evolved their different shapes by studying a gene that controls whether teeth develop as simple incisors or complex molars with multiple cusps.
- Evolutionary Health and Aging
A Study Of The Blood Lipoids And Blood Protein In Canadian Eastern Arctic Eskimos
This 1937 study examined blood fats and proteins in Canadian Arctic Inuit people to understand how their traditional high-fat diet affected their metabolism.
- Evolutionary Health and Aging
A Unique Hominin Menu Dated To 1.95 Million Years Ago
Scientists discovered that our early human ancestors ate a diverse diet including fish, turtles, and small animals 1.95 million years ago, not just large mammals.
- Evolutionary Health and Aging
A Unique Hominin Menu Dated To 1.95 Million Years Ago Copy
New archaeological evidence shows our human ancestors 1.95 million years ago ate a surprisingly diverse diet including fish, turtles, and other aquatic animals, not just large land mammals.
- Evolutionary Health and Aging
About Gladiators And A Sacred Disease
This journal issue explores various cutting-edge medical treatments including the ketogenic diet for epilepsy and gut microbiome transplants for brain health.
- Evolutionary Health and Aging
Aging Body Composition And Lifestyle The 1999 The American Journal Of Cl
This study found that staying physically active helps preserve muscle mass and reduce body fat as we age, with especially strong benefits for postmenopausal women.
- Evolutionary Health and Aging
An Unshakable Middle Paleolithic Trends Versus Conservatism In The Predatory Niche And Their Social Ramifications
Ancient humans 200,000 years ago had remarkably stable hunting and eating patterns focused on large game animals that remained unchanged for thousands of generations.
- Evolutionary Health and Aging
Animal Protein Intake Is Inversely Associated With Mortality In Older Adults The InCHIANTI Study
A 20-year study of older Italian adults found that eating more animal protein was linked to lower risk of death, challenging previous research favoring plant proteins.
- Evolutionary Health and Aging
Anserine Carnosine Supplementation Suppresses The Expression Of The Inflammatory Chemokine CCL24 In Peripheral Blood Mononuclear Cells From Elderly People
A supplement combining two amino acids, anserine and carnosine, helped reduce inflammation markers and preserve memory in older adults over three months.
- Evolutionary Health and Aging
Archaeological Evidence For Two Separate Dispersals Of Neanderthals Into Southern Siberia
Archaeological evidence reveals that Neanderthals migrated to southern Siberia in at least two separate waves, with the later group originating from eastern Europe around 59,000-49,000 years ago.
- Evolutionary Health and Aging
Big Brains, Meat, Tuberculosis, And The Nicotinamide Switches Co Evolutionary Relationships With Modern Repercussions
This research explores how eating meat provided essential nutrients that may have been crucial for human brain development throughout evolution.
- Evolutionary Health and Aging
Blood Biomarker Profiles And Exceptional Longevity Comparison Of Centenarians And Non‑centenarians In A 35‑year Follow‑up Of The Swedish AMORIS Cohort
Swedish researchers found that people who lived to 100 had better blood test values for cholesterol, blood sugar, and organ function starting from age 65.
- Evolutionary Health and Aging
Blood Biomarker Profiles And Longevity
Researchers found that people who lived to 100 had healthier blood test results decades earlier, suggesting certain biomarkers may predict exceptional longevity.
- Evolutionary Health and Aging
BLOOD, BULBS, AND BUNODONTS ON EVOLUTIONARY ECOLOGY AND THE DIETS OF ARDIPITHECUS, AUSTRALOPITHECUS, AND EARLY HOMO
Scientists studied what our early human ancestors ate and found they likely had varied diets rather than relying on just meat or just plants.
- Evolutionary Health and Aging
Bronze Age Population Dynamics And The Rise Of Dairy Pastoralism On The Eastern Eurasian Steppe
Researchers studied ancient DNA from Mongolia to understand how dairy farming spread and shaped human genetics over thousands of years.
- Evolutionary Health and Aging
Can Older Patients Adopt And Maintain A Ketogenic Diet An Observational Study In Support Of Clinical Trials In Older Patients
A study of 200 patients over age 65 found that most could successfully follow a ketogenic diet and saw benefits for weight loss, diabetes control, and potentially cancer outcomes.
- Evolutionary Health and Aging
Carnivore Hypothesis Revisited
This research explores how eating mostly meat during human evolution may have led to insulin resistance genes that now contribute to diabetes risk in modern high-carb diets.
- Evolutionary Health and Aging
Cell Metabolism Perspective Fasting, Circadian Rhythms, And Time Restricted Feeding In Healthy Lifespan
Research shows that fasting periods and eating only during certain hours of the day can trigger beneficial metabolic changes that may help prevent disease and promote healthy aging.
- Evolutionary Health and Aging
Chemical Profiling Of Ancient Hearths Reveals Recurrent Salmon Use In Ice Age Beringia
Scientists analyzed ancient cooking fires from 13,000 years ago and discovered that early humans in Alaska regularly ate salmon, showing fish was more important in prehistoric diets than previously known.
- Evolutionary Health and Aging
Chimpanzee Super Strength And Human Skeletal Muscle Evolution
Scientists discovered that chimpanzees are about 1.35 times stronger than humans because their muscles contain more fast-twitch fibers, not because individual muscle fibers are stronger.
- Evolutionary Health and Aging
Circulating Glycotoxins And Dietary Advanced Glycation Endproducts Two Links To Inflammatory Response, Oxidative Stress, And Aging
This study found that eating foods high in advanced glycation end products (AGEs) - compounds formed when foods are cooked at high heat - increases inflammation and aging-related damage in the body.
- Evolutionary Health and Aging
Climate Human Interaction Associated With Southeast Australian Megafauna Extinction Patterns
Researchers found that ancient climate changes and early human settlements together caused the extinction of large animals in Australia around 50,000 years ago.
- Evolutionary Health and Aging
Climate, Environment And Early Human Innovation Stable Isotope And Faunal Proxy Evidence From Archaeological Sites (98 59ka) In The Southern Cape, South Africa
Ancient human innovations like toolmaking weren't directly caused by climate changes, according to new evidence from South African archaeological sites dating back 98,000 years.
- Evolutionary Health and Aging
Combined Dental Wear And Cementum Analyses In Ungulates Reveal The Seasonality Of Neanderthal Occupations In Covalejos Cave (Northern Iberia)
Researchers analyzed ancient animal teeth to discover when Neanderthals hunted and lived in Spanish caves, revealing seasonal patterns of early human behavior.
- Evolutionary Health and Aging
Conjugated Linoleic Acid Historical Context And Implications
Conjugated linoleic acid (CLA), a beneficial fat found naturally in grass-fed meat and dairy, shows promise for fighting cancer and inflammation but human studies show mixed results.
- Evolutionary Health and Aging
Deep Coalescent History Of The Hominin Lineage
Researchers used genetic analysis to trace human population changes back 5-7 million years, revealing insights about early human evolution that could inform our understanding of longevity.
- Evolutionary Health and Aging
DHEAS And Human Development An Evolutionary Perspective
This research explores how DHEAS, a hormone produced by the adrenal glands, may have played a crucial role in human brain evolution and childhood development between ages 4-12.
- Evolutionary Health and Aging
Dietary Habits, Anthropometric Features And Daily Performance In Two Independent Long Lived Populations From Nicoya Peninsula (Costa Rica) And Ogliastra (Sardinia)
Researchers studied the diets of very elderly people in Costa Rica and Sardinia, finding that both long-lived populations eat mostly plant foods with regular dairy and meat consumption.
- Evolutionary Health and Aging
Dietary Soy And Natto Intake And Cardiovascular Disease Mortality In Japanese Adults The Takayama Study1
A large Japanese study found that eating natto (fermented soybeans) was linked to a 25% lower risk of dying from cardiovascular disease over 16 years.
- Evolutionary Health and Aging
Different Environmental Variables Predict Body And Brain Size Evolution In Homo
Researchers found that temperature drove human body size evolution over the past million years, while environmental productivity influenced brain size development.
- Evolutionary Health and Aging
Different Selective Pressures Shape The Molecular Evolution Of Color Vision In Chimpanzee And Human Populations
Researchers found that humans and chimpanzees evolved different color vision abilities despite being closely related, with humans showing more genetic variation in their "red" color vision gene.
- Evolutionary Health and Aging
Earliest Archaeological Evidence Of Persistent Hominin Carnivory
Archaeological evidence from Kenya shows our ancestors were regularly eating meat 2 million years ago, making carnivory a key part of human evolution.
- Evolutionary Health and Aging
Earliest Fire In Africa Towards The Convergence Of Archaeological Evidence And The Cooking Hypothesis
This study examines archaeological evidence for when early humans first began using fire for cooking, which may have been crucial for human brain development and metabolism.
- Evolutionary Health and Aging
Effects Of Hyperthyroidism In The Development Of The Appendicular Skeleton And Muscles Of Zebrafish, With Notes On Evolutionary Developmental Pathology (Evo Devo Path)
Researchers studied how thyroid hormone T3 affects bone and muscle development in zebrafish, revealing insights into how thyroid function impacts growth across species including humans.
- Evolutionary Health and Aging
Elastin Derived Extracellular Matrix Fragments Drive Aging Through Innate Immune Activation
Scientists discovered that fragments from broken-down elastin (a protein that keeps tissues flexible) circulate in blood and accelerate aging by triggering harmful inflammation.
- Evolutionary Health and Aging
Environmental Selection During The Last Ice Age On The Mother To Infant Transmission Of Vitamin D And Fatty Acids Through Breast Milk
Researchers discovered that genetic changes helping mothers pass more vitamin D and healthy fats to babies through breast milk were naturally selected during the Ice Age in extreme northern climates.
- Evolutionary Health and Aging
Estimating The Ages Of Selection Signals From Different Epochs In Human History
Researchers developed a method to estimate when genetic changes that helped humans survive occurred throughout history, from ancient migrations to the rise of agriculture.
- Evolutionary Health and Aging
Etho Eco Morphological Mismatches, An Overlooked Phenomenon In Ecology, Evolution And Evo Devo That Supports ONCE (Organic Nonoptimal Constrained Evolution) And The Key Evolutionary Role Of Organismal Behavior
Scientists found that animals' bodies often don't perfectly match their environments because evolution is constrained by genetics and behavior, challenging the idea that organisms are optimally designed.
- Evolutionary Health and Aging
Evidence Of Different Metabolic Phenotypes In Humans
Scientists discovered that each person has a unique metabolic "fingerprint" that remains consistent over time, which could help detect diseases earlier.
- Evolutionary Health and Aging
Evidence On Chronic Ketosis In Traditional Arctic Populations
This study challenges claims that traditional Arctic peoples avoided ketosis, suggesting they may have actually been in ketosis regularly despite low-carb diets.
- Evolutionary Health and Aging
Evolution, Medicine, And Public Health [2019] Pp. 183–189 Doi 10.1093 Emph Eoz026 Human Enhancement Genetic Engineering And Evolution
This research examines how genetic engineering to enhance human abilities could affect our evolution and requires careful consideration of complex biological interactions and ethical boundaries.
- Evolutionary Health and Aging
Evolutionary Basis For The Human Diet Consequences For Human Health
This research traces how human diets evolved over millions of years, from fruit-eating ancestors to meat-rich diets to modern grain-based foods, explaining today's health challenges.
Disclaimer: this library, including every summary, is for general informational and educational purposes only. It does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before changing your diet, exercise, or health regimen, or if you have questions about a medical condition.