Metabolic
Library
1,810 peer-reviewed papers, each with a plain-language summary and the source document. The evidence behind the VALIA method, kept where you can read it.
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1,810 papers
· 13 topics
Liver and Kidney Health results
166 results in Liver and Kidney Health · page 1 of 4
- Liver and Kidney Health
A Dietary Ketone Ester Mitigates Histological Outcomes Of NAFLD And Markers Of Fibrosis In High Fat Diet Fed Mice
A ketone supplement reduced liver fat buildup and inflammation in mice eating a high-fat diet, suggesting potential benefits for fatty liver disease.
- Liver and Kidney Health
A History Of Diabetes Mellitus Or How A Disease Of The Kidneys Evolved Into A Kidney Disease
This historical review traces how diabetes was originally thought to be a kidney disease for centuries before scientists discovered it actually originates from problems with blood sugar and insulin.
- Liver and Kidney Health
A History Of Obesity, Or How What Was Good Became Ugly And Then Bad
This article traces how obesity transformed from being considered desirable throughout most of human history to being recognized as a serious health condition linked to kidney disease.
- Liver and Kidney Health
Acute Oxalate Nephropathy Caused By Excessive Vegetable Juicing And Concomitant Volume Depletion
A 68-year-old man developed severe kidney failure requiring permanent dialysis after drinking large amounts of spinach-based vegetable juice daily for six months.
- Liver and Kidney Health
Adiposity Metabolomic Biomarkers And Risk Of Non 2022 The American Journal
Researchers identified specific blood chemicals that link obesity to fatty liver disease, potentially helping predict and prevent this common condition.
- Liver and Kidney Health
Advanced Glycation Endproducts Induce Podocyte Apoptosis By Activation Of The FOXO4 Transcription Factor
Researchers found that sugar-damaged proteins (advanced glycation endproducts) kill important kidney cells called podocytes, which helps explain how diabetes damages kidneys.
- Liver and Kidney Health
Alternate Day Ketogenic Diet Feeding Protects Against Heart Failure Through Preservation Of Ketogenesis In The Liver
Researchers found that eating a ketogenic diet every other day, rather than continuously, better protects heart health by preserving the liver's ability to produce ketones.
- Liver and Kidney Health
An Integrated Proteomics And Metabolomics Strategy For The Mechanism Of Calcium Oxalate Crystal Induced Kidney Injury
Researchers discovered how calcium oxalate crystals (the main component of kidney stones) damage kidneys by triggering inflammation and oxidative stress through specific cellular pathways.
- Liver and Kidney Health
Analytical Methods For Oxalate Quantification The Ubiquitous Organic Anion
This research reviews different laboratory methods scientists use to measure oxalate levels, a compound found in many foods that can contribute to kidney stones.
- Liver and Kidney Health
Association Between Triglycerides And Residual Cardiovascular Risk In Patients With Type 2 Diabetes Mellitus And Established Cardiovascular Disease (From The Bypass Angioplasty Revascularization Investigation 2 Diabetes [BARI 2D] Trial)
This study found that higher triglyceride levels significantly increase the risk of heart attacks, strokes, and death in people with both type 2 diabetes and existing heart disease.
- Liver and Kidney Health
Baseline HOMA IR And Circulating FGF21 Levels Predict NAFLD Improvement In Patients Undergoing A Low Carbohydrate Dietary Intervention For Weight Loss A Prospective Observational Pilot Study
Researchers found that blood markers can predict which obese patients will see the most liver health improvement from low-carb diets.
- Liver and Kidney Health
Can Ketogenic Dietary Interventions Slow Disease Progression In ADPKD
Researchers are investigating whether ketogenic diets might help slow the progression of ADPKD, a common inherited kidney disease, though human studies are still needed.
- Liver and Kidney Health
Can Ketogenic Dietary Interventions Slow Disease Progression In ADPKD What We Know And What We Don T
Researchers are exploring whether ketogenic diets might help slow kidney disease progression in people with ADPKD, a common inherited condition that causes kidney cysts.
- Liver and Kidney Health
Cancers In Australia In 2010 Attributable To Overweight And Obesity
This Australian research examined how many cancer cases in 2010 were linked to being overweight or obese, finding strong connections to multiple cancer types.
- Liver and Kidney Health
Chronic Dietary Erythritol Exposure Elevates Plasma Erythritol Concentration In Mice But Does Not Cause Weight Gain Or Modify Glucose Homeostasis
This letter challenges a study about cruciferous vegetables and diabetes risk, arguing that how these vegetables are prepared and cooked significantly affects their potential health benefits.
- Liver and Kidney Health
CLINICAL CALORIMETRY XLV. PROLONGED MEAT DIETS WITH A STUDY OF KIDNEY FUNCTION AND KETOSIS
Two men ate only meat for one year while researchers monitored their kidney function and metabolism, finding they remained healthy despite concerns about this extreme diet.
- Liver and Kidney Health
Contribution Of Dietary Oxalate And Oxalate Precursors To Urinary Oxalate Excretion
This research examines how oxalate from food and the body's own production contributes to kidney stone formation, particularly calcium oxalate stones.
- Liver and Kidney Health
Current Evidence Concerning Effects Of Ketogenic Diet And Intermittent Fasting In Patients With Nonalcoholic Fatty Liver
Researchers reviewed evidence on whether ketogenic diets and intermittent fasting can help treat nonalcoholic fatty liver disease, a common condition affecting 25% of people globally.
- Liver and Kidney Health
Data Set For Characterization Of The Glycosylation Status Of Hepatic Glycoproteins In Mice Fed A Low Carbohydrate Ketogenic Diet
A ketogenic diet changed how proteins are modified with sugar molecules in mouse livers, which could affect liver function and metabolic health.
- Liver and Kidney Health
Diabetes Research A Perspective From The National Institute Of Diabetes And Digestive And Kidney Diseases
The National Institute of Diabetes and Digestive and Kidney Diseases outlines their research priorities as diabetes rates climb and the disease increasingly affects younger people and multiple organ systems.
- Liver and Kidney Health
Dietary Care For ADPKD Patients Current Status And Future Directions
Researchers are exploring how specific diets, particularly low-calorie and ketogenic approaches, might help slow the progression of ADPKD, a common genetic kidney disease.
- Liver and Kidney Health
Dietary Program For AD PCKD On Dialysis
Researchers developed a specialized plant-based, low-carb diet program to help slow kidney disease progression in people with inherited polycystic kidney disease.
- Liver and Kidney Health
Dietary Protein Intake And Renal Function
This research review found no evidence that eating high amounts of protein damages kidney function in healthy people, despite common concerns about protein "stressing" the kidneys.
- Liver and Kidney Health
Direct Cardiac Actions Of Sodium Glucose Cotransporter 2 Inhibitors Target Pathogenic Mechanisms Underlying Heart Failure In Diabetic Patients
SGLT2 inhibitor diabetes medications provide direct heart protection benefits beyond blood sugar control, which may explain why they reduce heart failure and cardiovascular death.
- Liver and Kidney Health
Do Ketone Bodies Mediate The Anti Seizure Effects Of The Ketogenic Diet
Researchers are investigating whether ketone bodies (molecules produced during ketosis) are responsible for the ketogenic diet's ability to reduce seizures in epilepsy patients.
- Liver and Kidney Health
Effect Of 2 Year Caloric Restriction On Organ And Tissue Size In Nonobese 21 To 50 Year Old Adults In A Randomized Clinical Trial The CALERIE Study
A two-year study found that moderate calorie restriction in healthy adults led to fat loss (especially dangerous belly fat) while preserving most muscle and organ tissue.
- Liver and Kidney Health
Effect Of A Ketogenic Diet On Hepatic Steatosis And Hepatic Mitochondrial Metabolism In Nonalcoholic Fatty Liver Disease
A 6-day ketogenic diet reduced fatty liver by 31% in overweight people by changing how the liver processes fats, shifting from fat storage to fat burning.
- Liver and Kidney Health
Effects Of A Ketogenic Diet In Overweight Women With Polycystic Ovary Syndrome
A 12-week ketogenic Mediterranean diet helped overweight women with PCOS lose weight, improve insulin sensitivity, and balance hormones that affect fertility and metabolism.
- Liver and Kidney Health
Effects Of Calorie Restriction On Health Span And Insulin Resistance Classic Calorie Restriction Diet Vs. Ketosis Inducing Diet
This review compared different calorie restriction approaches and found that reducing calories can improve insulin sensitivity and metabolic health, with ketogenic Mediterranean diets showing particularly strong benefits.
- Liver and Kidney Health
Effects Of Low Animal Protein Or High Fiber Diets On Urine Composition In Calcium Nephrolithiasis
Researchers studied whether eating less animal protein or more fiber could help prevent kidney stone recurrence, but found no significant benefit for most patients.
- Liver and Kidney Health
Efficacy And Safety Of Carnitine Supplementation On NAFLD A Systematic Review And Meta Analysis
L-carnitine supplements may help improve liver function and cholesterol levels in people with fatty liver disease, though more research is needed.
- Liver and Kidney Health
Expression Analysis Of Oxalate Metabolic Pathway Genes Reveals Oxalate Regulation Patterns In Spinach
Researchers studied why some spinach varieties contain more oxalates (compounds that can interfere with nutrient absorption and kidney health) than others.
- Liver and Kidney Health
Factors Associated With 24 Hour Urinary Volume The Swiss Salt Survey
Researchers studied what factors affect daily urine output in healthy people, finding that higher urine volume may help protect kidney function over time.
- Liver and Kidney Health
Fasting Time And Lipid Parameters Association With Hepatic Steatosis — Data From A Random Population Sample
This study found that how long you fast before blood tests significantly affects cholesterol and triglyceride levels, and fatty liver disease makes these changes even more pronounced.
- Liver and Kidney Health
Fatty Liver Due To Increased De Novo Lipogenesis Alterations In The Hepatic Peroxisomal Proteome
Researchers found that when the liver makes too much fat internally, it causes major changes in cellular structures called peroxisomes that help break down fats.
- Liver and Kidney Health
Feasibility And Impact Of Ketogenic Dietary Interventions In PCKD
A clinical trial found that ketogenic diets are safe and feasible for people with polycystic kidney disease and may help improve kidney function while reducing body fat.
- Liver and Kidney Health
Fluctuations In Metabolite Content In The Liver Of Magnesium Deficient Rats
Researchers found that magnesium deficiency significantly disrupts liver metabolism, affecting how the body processes sugars, fats, and amino acids at the cellular level.
- Liver and Kidney Health
Fractional Magnesium Absorption Is Significantly Lower In Human Subjects From A Meal Served With An Oxalate Rich Vegetable, Spinach, As Compared With A Meal Served With Kale, A Vegetable With A Low Oxalate Content
This study found that your body absorbs significantly less magnesium from meals containing spinach compared to kale due to spinach's high oxalate content that blocks mineral absorption.
- Liver and Kidney Health
From The Ketogenic Diet To The Mediterranean Diet The Potential Dietary Therapy In Patients With Obesity After CoVID 19 Infection (Post CoVID Syndrome)
Researchers propose using a ketogenic diet followed by a Mediterranean diet, combined with exercise, to help people with obesity recover from long COVID symptoms.
- Liver and Kidney Health
Fructose Metabolism, Cardiometabolic Risk, And The Epidemic Of Coronary Artery Disease
This research explains how fructose (fruit sugar) is processed differently by the body than other sugars, contributing to heart disease, diabetes, and metabolic problems even beyond its calorie content.
- Liver and Kidney Health
Function And Mechanism Of Histone β Hydroxybutyrylation In Health And Disease
Researchers discovered that beta-hydroxybutyrate (a ketone your body makes during fasting or low-carb diets) can chemically modify proteins in your cells in ways that may protect against heart disease, kidney problems, and other metabolic disorders.
- Liver and Kidney Health
Gene Regulation In Primates Evolves Under Tissue Specific Selection Pressures
Scientists found that genes controlling metabolism in the liver and kidneys have evolved differently in humans compared to other primates, likely due to changes in diet over time.
- Liver and Kidney Health
Gilbert’s Syndrome Successfully Treated With The Paleolithic Ketogenic Diet
A case study found that a paleolithic ketogenic diet reversed elevated bilirubin levels and symptoms like fatigue and migraines in a patient with Gilbert's syndrome.
- Liver and Kidney Health
He Influence Of A Cooked Meat Meal On Estimated Glomerular Filtration Rate
This study examined whether eating a normal portion of cooked meat temporarily affects blood test results that measure kidney function.
- Liver and Kidney Health
Hepatic Steatosis, Inflammation, And ER Stress In Mice Maintained Long Term On A Very Low Carbohydrate Ketogenic Diet
Researchers found that mice on long-term ketogenic diets developed fatty liver disease and liver inflammation, despite staying lean and maintaining normal insulin sensitivity.
- Liver and Kidney Health
High Fat Diet Induced Kidney Alterations In Rats With Metabolic Syndrome Endothelial Dysfunction And Decreased Antioxidant Defense
A high-fat diet damages kidney blood vessels and reduces antioxidant defenses before kidney function declines, but vitamin B6 treatment may help protect against this damage.
- Liver and Kidney Health
High Plasma SRAGE (Soluble Receptor For Advanced Glycation End Products) Is Associated With Slower Carotid Intima Media Thickness Progression And Lower Risk For First Time Coronary Events And Mortality
Higher levels of a protective protein called sRAGE in the blood are linked to slower artery thickening and lower risk of heart disease and death.
- Liver and Kidney Health
High Plasma Uric Acid Concentration Causes And Consequences
High uric acid levels in blood can either protect against cell damage or increase disease risk, depending on whether the elevation is temporary or chronic.
Disclaimer: this library, including every summary, is for general informational and educational purposes only. It does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before changing your diet, exercise, or health regimen, or if you have questions about a medical condition.