Metabolic
Library
1,810 peer-reviewed papers, each with a plain-language summary and the source document. The evidence behind the VALIA method, kept where you can read it.
Educational information only. Not medical advice, diagnosis or treatment. For anything about your own health, speak with a clinician. To become a patient, start at our contact page.
1,810 papers
· 13 topics
Heart Health results
360 results in Heart Health · page 8 of 8
- Heart Health
Thematic Review Series The Pathogenesis Of Atherosclerosis. An Interpretive History Of The Cholesterol Controversy, Part IV The 1984 Coronary Primary Prevention Trial Ends It—almost
The landmark 1984 Coronary Primary Prevention Trial proved that lowering cholesterol with medication reduces heart attacks by 19%, finally convincing doctors to treat high cholesterol.
- Heart Health
Thematic Review Series The Pathogenesis Of Atherosclerosis. An Interpretive History Of The Cholesterol Controversy, Part V The Discovery Of The Statins And The End Of The Controversy
This historical review describes how the discovery of statin drugs in the 1980s finally proved that lowering cholesterol with medication dramatically reduces heart disease risk.
- Heart Health
Thin Walled Microvessels In Human Coronary Atherosclerotic Plaques Show Incomplete Endothelial Junctions Relevance Of Compromised Structural Integrity For Intraplaque Microvascular Leakage
Researchers found that tiny blood vessels within heart artery plaques have structural weaknesses that allow dangerous leaking, potentially leading to plaque rupture and heart attacks.
- Heart Health
Treatments For Skeletal Muscle Abnormalities In Heart Failure Sodium Glucose Transporter 2 And Ketone Bodies
Researchers are investigating whether SGLT2 inhibitor medications could help heart failure patients by improving muscle energy problems that cause exercise intolerance.
- Heart Health
Trends In Risk Profiles Among Adults With Cardiovascular Disease USA
A 20-year study found that Americans with heart disease showed mixed progress on health factors, with cholesterol control improving significantly while weight management and blood sugar control worsened.
- Heart Health
Trial Level Surrogacy Of Non High Density And Low Density Lipoprotein Cholesterol Reduction On The Clinical Efficacy Of Statins
This study found that cholesterol level improvements from statin medications don't reliably predict how much they actually reduce heart attacks and deaths.
- Heart Health
Tufts MetHealth Article
American heart health has gotten significantly worse over the past two decades, with rising obesity and diabetes being the main culprits behind this alarming trend.
- Heart Health
Tunica Media Dysfunction And Primary Hypertension
This research proposes that primary high blood pressure may be caused by damage to the middle layer of artery walls, which affects how blood vessels contract and relax.
- Heart Health
UK Food Standards Agency Workshop Report Carbohydrate And Cardiovascular Risk
UK researchers reviewed studies examining how different types of carbohydrates affect heart disease risk to guide future nutrition recommendations.
- Heart Health
Use Of Dietary Linoleic Acid For Secondary Prevention Of Coronary Heart Disease And Death Evaluation Of Recovered Data From The Sydney Diet Heart Study And Updated Meta Analysis
A study found that replacing saturated fats with omega-6 linoleic acid (from safflower oil) may actually increase death rates from heart disease rather than prevent it.
- Heart Health
Use Of Lipoprotein(a) In Clinical Practice(1)
Lipoprotein(a) or Lp(a) is an important blood marker that can predict heart disease risk, affecting about 20% of people, and should be tested more routinely.
- Heart Health
Usual Dietary Glycemic Load Is Associated With Cardiometabolic Risk Factors In Physically Active Brazilian Middle Aged Men
Higher glycemic load diets were linked to worse heart health markers in physically active middle-aged men, suggesting that even exercise may not fully protect against the effects of high blood sugar-spiking foods.
- Heart Health
Variation In The Human Lipidome Associated With Coffee Consumption As Revealed By Quantitative Targeted Metabolomics
Researchers found that vitamin B12 directly supports gut cell health by improving fat metabolism, energy production, and cell repair processes that are essential for intestinal barrier function.
- Heart Health
Vasa Vasorum In Plaque Angiogenesis, Metabolic Syndrome, Type 2 Diabetes Mellitus, And Atheroscleropathy A Malignant Transformation
This research explores how diabetes and metabolic syndrome cause dangerous new blood vessels to grow inside artery plaques, making them more likely to rupture and cause heart attacks.
- Heart Health
Vascular Function In Response To Fat Intake
A study found that eating high-fat ground beef actually improved blood vessel function and lowered blood pressure in men, contrary to common beliefs about red meat.
- Heart Health
Vegetables And CV Risk
A large study of 400,000 adults found that eating raw vegetables was linked to lower heart disease risk, while cooked vegetables showed no protective benefit.
- Heart Health
Vegetarian Diets And Blood Pressure Among White Subjects Results From The Adventist Health Study 2 Ahs 2
A study of 500 people found that vegetarians, especially vegans, had significantly lower blood pressure and were less likely to develop hypertension than meat-eaters.
- Heart Health
Vegetarian Diets And Cardiovascular Risk Factors In Black Members Of The Adventist Health Study 2
A study of Black Americans found that vegetarian and vegan diets were linked to significantly lower rates of high blood pressure, diabetes, high cholesterol, and obesity compared to meat-eating diets.
- Heart Health
Visceral Adiposity, Subcutaneous Adiposity, And Se
Belly fat (visceral fat) increases the risk of severe COVID-19, but fat under the skin (subcutaneous fat) does not.
- Heart Health
Vitamin D Intake Is Inversely Related To Risk Of Developin 2012 The American
Higher vitamin D intake from food and supplements was linked to lower risk of developing metabolic syndrome over 20 years in young adults.
- Heart Health
Vulnerable Plaque Formation From Obstruction Of Vasa Vasorum By Homocysteinylated And Oxidized Lipoprotein Aggregates Complexed With Microbial Remnants And LDL Autoantibodies
Researchers propose that heart-damaging plaques form when cholesterol particles carrying germs get stuck in tiny blood vessels that feed artery walls, causing inflammation and creating vulnerable spots that can trigger heart attacks.
- Heart Health
Weight Set Point Theory And The High Density Lipop
Long-distance runners have higher "good" HDL cholesterol primarily because they maintain lower body fat, not because running itself directly boosts HDL levels.
- Heart Health
What Do US Physicians And Patients Think About Lipid‐Lowering Therapy And Goals Of Treatment Results From The GOULD Registry
Most patients with heart disease don't understand why they're taking cholesterol medications or what their cholesterol goals are, creating a major gap in care.
- Heart Health
Whole Grain Rye Intake, Reflected By A Biomarker, Is Associated With Favorable Blood Lipid Outcomes In Subjects With The Metabolic Syndrome – A Randomized Study
This study found that eating whole grain rye was linked to better cholesterol levels in people with metabolic syndrome, a condition that increases heart disease risk.
Disclaimer: this library, including every summary, is for general informational and educational purposes only. It does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before changing your diet, exercise, or health regimen, or if you have questions about a medical condition.