Metabolic
Library
1,810 peer-reviewed papers, each with a plain-language summary and the source document. The evidence behind the VALIA method, kept where you can read it.
Educational information only. Not medical advice, diagnosis or treatment. For anything about your own health, speak with a clinician. To become a patient, start at our contact page.
1,810 papers
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1,810 results · page 15 of 38
- Evolutionary Health and Aging
Favorable Ecological Circumstances Promote Life Expectancy In Chimpanzees Similar To That1 Of Human Hunter Gatherers
Chimpanzees living in ideal conditions can live as long as human hunter-gatherers, suggesting that environment plays a major role in natural lifespan.
- Liver and Kidney Health
Feasibility And Impact Of Ketogenic Dietary Interventions In PCKD
A clinical trial found that ketogenic diets are safe and feasible for people with polycystic kidney disease and may help improve kidney function while reducing body fat.
- Brain and Nerve Health
Feasibility And Safety Of A Combined Metabolic Strategy In Glioblastoma Multiforme
Researchers found that brain cancer patients could safely follow a combined approach of periodic 5-7 day fasts and a ketogenic diet for several months.
- Brain and Nerve Health
Feasibility Of An MI CBT Ketogenic Adherence Program For Older Adults With Mild Cognitive Impairment
A small study found that older adults with mild memory problems who followed a ketogenic diet for 6 weeks showed improved thinking test scores.
- Gut Health
Fecal Microbiota And Bile Acid Interactions With Systemic And Adipose Tissue Metabolism In Diet Induced Weight Loss Of Obese Postmenopausal Women
A very low calorie diet changed gut bacteria and bile acids in obese postmenopausal women, which correlated with improvements in metabolism and fat tissue inflammation.
- Heart Health
Ffect Of Low Glycaemic Index Or Load Dietary Patterns On Glycaemic Control And Cardiometabolic Risk Factors In Diabetes Systematic Review And Meta Analysis Of Randomised Controlled Trials
This large study found that eating foods with a low glycemic index (which cause smaller blood sugar spikes) helps people with diabetes better control their blood sugar and improve heart health markers.
- Gut Health
Fiber And Colorectal Diseases Separating Fact From Fiction
This research challenges common beliefs about fiber, finding limited evidence that high-fiber diets prevent colorectal cancer, constipation, or other digestive diseases.
- Mental Health
Fiber Intake And Fiber Intervention In Depression And Anxiety A Systematic Review And Meta Analysis Of Observational Studies And Randomized Controlled Trials
A large review found that people who eat more fiber tend to have less depression and anxiety, but fiber supplements don't appear to improve mood.
- Brain and Nerve Health
Fibromyalgia Syndrome Improved Using A Mostly Raw Vegetarian Diet An Observational Study
A study found that eating a mostly raw vegetarian diet significantly reduced fibromyalgia symptoms including pain, fatigue, and depression in most participants.
- Evolutionary Health and Aging
First Anatomical Network Analysis Of Fore And Hindlimb Musculoskeletal Modularity In Bonobos, Common Chimpanzees, And Humans
Scientists studied how muscles and bones connect differently in humans compared to our closest primate relatives, revealing how human limbs evolved for specialized walking versus climbing.
- Environment and Health
Fish And Seafood, Heavy Metal Exposure
This study found that fish and seafood in Central Asia contain concerning levels of toxic metals like mercury and lead that could pose health risks.
- Heart Health
Fish Consumption, Sleep, Daily Functioning, And Heart Rate Variability
Eating fatty fish three times per week improved sleep quality, daily energy levels, and heart health markers compared to other protein sources.
- Hormone Health
Fish Oil Enriched N 3 Polyunsaturated Fatty Acids Improve Ketogenic Low Carbohydrate High Fat Diet Caused Dyslipidemia, Excessive Fat Accumulation, And Weight Control In Rats
Adding fish oil supplements to ketogenic diets helped rats lose weight and improved unhealthy cholesterol changes that the high-fat diet alone caused.
- Hormone Health
Fish Oil Enriched N 3 Polyunsaturated Fatty Acids Improve Ketogenic Low Carbohydrate High Fat Diet Caused Dyslipidemia, Excessive Fat Accumulation, And Weight Control In Rats
Fish oil supplements helped rats counteract negative side effects like poor cholesterol levels and fat buildup caused by ketogenic low-carb, high-fat diets.
- Nutrition and Health
Fish Oil LC PUFAs Do Not Affect Blood Coagulation
A large study of over 600 patients found that fish oil supplements, even at high doses, do not increase bleeding risk or affect blood clotting.
- Mental Health
Fish Oils For Depression
Fish oil supplements may help with depression when added to antidepressants, but evidence is limited and they shouldn't replace prescribed medications.
- Heart Health
Flaxseed Consumption May Reduce Blood Pressure A Systemat 2015 The Journal
A review of 11 studies found that eating flaxseed may help lower blood pressure, especially when consumed as whole seeds for more than 12 weeks.
- Hormone Health
Flipping The Metabolic Switch Understanding And Applying The Health Benefits Of Fasting
Intermittent fasting triggers a "metabolic switch" where your body shifts from burning sugar to burning fat for energy, which may improve body composition and slow aging.
- Liver and Kidney Health
Fluctuations In Metabolite Content In The Liver Of Magnesium Deficient Rats
Researchers found that magnesium deficiency significantly disrupts liver metabolism, affecting how the body processes sugars, fats, and amino acids at the cellular level.
- Dental Health
Fluoride From Nutrient To Suspected Neurotoxin
A dental researcher reflects on how fluoride's reputation has shifted from being considered beneficial for teeth to potentially harmful for brain health over 60 years.
- Joint, Muscle Health and Exercise
Fluoride Exposure And Bone Status In Patients With Ch 2006 The American Jour
Patients receiving long-term intravenous nutrition had dangerously high fluoride levels that weakened their bones, mainly from drinking too many fluoride-containing beverages.
- Joint, Muscle Health and Exercise
Fluoride Exposure And Bone Status In Patients With Ch 2006 The American Jour(1)
Patients with chronic intestinal problems who receive nutrition through IV therapy often have dangerously high fluoride levels that weaken their bones.
- Nutrition and Health
Folate And Neural Tube Defects 2007 The American Journal Of Clinical Nutriti
Taking folic acid supplements before and during early pregnancy can prevent 25-30% of serious birth defects affecting the brain and spine called neural tube defects.
- Hormone Health
Food Addiction And Obesity Do Macronutrients Matter
Research explores whether specific nutrients like sugar and fat trigger addiction-like brain responses that contribute to overeating and obesity.
- Nutrition and Health
Food And Nutrient Intakes And Asthma Risk 2003 The American Journal Of Clini
This study found that drinking whole milk and eating apples and pears may protect against asthma, while soy beverages were linked to increased asthma risk.
- Environment and Health
Food Miles And The Relative Climate Impacts Of Food Choices In The United States
This study found that choosing what you eat matters more for reducing your carbon footprint than buying locally-grown food.
- Nutrition and Health
Food Preference Patterns In A UK Twin Cohort
A study of over 2,000 twins found that our food preferences are significantly influenced by our genes, with some taste preferences being more than 50% heritable.
- Nutrition and Health
Food Restriction Circadian Cycle
Research in female rats found that eating only during inactive hours (equivalent to daytime eating in humans) may disrupt reproductive function and ovulation patterns.
- Nutrition and Health
Food Sources Of Animal Protein In Relation To Overall And Cause Specific Mortality—Causal Associations Or Confounding An Analysis Of The EPIC Heidelberg Cohort
A German study found that the apparent health risks from red meat and benefits from dairy may be largely explained by lifestyle factors like smoking and drinking rather than the foods themselves.
- Nutrition and Health
Food Texture Trumps Food Processing In The R 2022 The American Journal Of Cl
Food texture affects how fast we eat and how much we consume more than whether foods are ultra-processed or minimally processed.
- Mental Health
Foods And Dietary Profiles Associated With Food Add 2015 Addictive Behavior
This study found that people who show signs of food addiction tend to eat more candy, takeout, and sweets while eating fewer whole grains and healthy breakfast cereals.
- Evolutionary Health and Aging
Fossils From Mille Logya, Afar, Ethiopia, Elucidate The Link Between Pliocene Environmental Changes And Homo Origins
New fossil discoveries in Ethiopia show how environmental changes around 3 million years ago may have triggered the evolution of early humans from their ape-like ancestors.
- Liver and Kidney Health
Fractional Magnesium Absorption Is Significantly Lower In Human Subjects From A Meal Served With An Oxalate Rich Vegetable, Spinach, As Compared With A Meal Served With Kale, A Vegetable With A Low Oxalate Content
This study found that your body absorbs significantly less magnesium from meals containing spinach compared to kale due to spinach's high oxalate content that blocks mineral absorption.
- Hormone Health
Free Sugars And Total Fat Are Important Characteristics Of A 2016 The Journa
A large study of children found that diets high in both added sugars and fats lead to greater body fat accumulation during childhood and adolescence.
- Liver and Kidney Health
From The Ketogenic Diet To The Mediterranean Diet The Potential Dietary Therapy In Patients With Obesity After CoVID 19 Infection (Post CoVID Syndrome)
Researchers propose using a ketogenic diet followed by a Mediterranean diet, combined with exercise, to help people with obesity recover from long COVID symptoms.
- Nutrition and Health
Frontiers In Nutrition 01 Frontiersin.org The Relationship Between Vitamin K And Metabolic Dysfunction Associated Fatty Liver Disease Among The United States Population National Health And Nutrition Examination Survey 2017–2018
Higher vitamin K intake may help protect against fatty liver disease, especially when vitamin K comes from food rather than supplements.
- Nutrition and Health
Fructose Consumption From Different Food Sources And 2023 The American Jour
This study found that fructose from sugary drinks harms metabolic health markers, while fructose from whole fruits actually provides protective benefits.
- Nutrition and Health
Fructose Drives De Novo Lipogenesis Affecting Metabolic Health
Research shows that fructose (fruit sugar) is more likely than glucose to trigger the liver's production of fat, which can lead to fatty liver disease and metabolic problems.
- Nutrition and Health
Fructose In Perspective
This research review finds that fructose (fruit sugar) is metabolized similarly to other sugars and may not be uniquely harmful compared to reducing total carbohydrate intake.
- Nutrition and Health
Fructose Induced KHK C Increases ER Stress And Modulates Hepatic Transcriptome To Drive Liver Disease In Diet Induced And Genetic Models Of NAFLD
Researchers discovered how fructose (fruit sugar) triggers a specific enzyme that causes liver stress and damage, contributing to fatty liver disease.
- Liver and Kidney Health
Fructose Metabolism, Cardiometabolic Risk, And The Epidemic Of Coronary Artery Disease
This research explains how fructose (fruit sugar) is processed differently by the body than other sugars, contributing to heart disease, diabetes, and metabolic problems even beyond its calorie content.
- Heart Health
Fructose Metabolism, Cardiometabolic Risk, And The Epidemic Of Coronary Artery Disease
This research explains how fructose (a type of sugar found in many foods) is processed differently by the body and may contribute to heart disease and metabolic problems.
- Heart Health
Fruit, Vegetable, And Legume Intake, And Cardiovas
A large international study found that eating more fruits, vegetables, and legumes (beans and lentils) significantly reduces the risk of heart disease and death.
- Joint, Muscle Health and Exercise
Fueling For And Recovering From Resistance Training The Periwork 2024 Nutri
A study of 305 competitive powerlifters found most eat carbs before training, protein after training, and use supplements like pre-workout formulas and creatine.
- Joint, Muscle Health and Exercise
Fueling For And Recovering From Resistance Training The Periwork 2024 Nutri(1)
A study of competitive powerlifters found most eat carbohydrates before and during training for energy, and protein afterward for recovery, while also using pre-workout supplements.
- Liver and Kidney Health
Function And Mechanism Of Histone β Hydroxybutyrylation In Health And Disease
Researchers discovered that beta-hydroxybutyrate (a ketone your body makes during fasting or low-carb diets) can chemically modify proteins in your cells in ways that may protect against heart disease, kidney problems, and other metabolic disorders.
- Gut Health
Functional Bowel Disorders A Roadmap To Guide The
Leading researchers created a roadmap for better understanding and treating functional bowel disorders like irritable bowel syndrome through improved brain-gut connection research.
- Gut Health
Functional Diagnostics And Therapeutic Effects Of Bile
Bile, a fluid made by your liver, plays crucial roles in digesting fats, eliminating cholesterol, and maintaining metabolic health, but can cause problems when this system is disrupted.
Disclaimer: this library, including every summary, is for general informational and educational purposes only. It does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before changing your diet, exercise, or health regimen, or if you have questions about a medical condition.