Metabolic
Library
1,810 peer-reviewed papers, each with a plain-language summary and the source document. The evidence behind the VALIA method, kept where you can read it.
Educational information only. Not medical advice, diagnosis or treatment. For anything about your own health, speak with a clinician. To become a patient, start at our contact page.
1,810 papers
· 13 topics
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1,810 results · page 2 of 38
- Brain and Nerve Health
A New Way To Produce Hyperketonemia Use Of Ketone Ester In A Case Of Alzheimer’s
Researchers tested a ketone ester drink as an alternative brain fuel for Alzheimer's patients, since their brains struggle to use glucose effectively.
- Brain and Nerve Health
A Non Invasive Determination Of Ketosis Induced Elimination Of Chronic Daytime Somnolence In A Patient
A ketogenic diet successfully eliminated chronic daytime sleepiness in a dementia patient by putting the body into ketosis, suggesting the brain may have repaired itself.
- Brain and Nerve Health
A Non Invasive Determination Of Ketosis Induced Elimination Of Chronic Daytime Somnolence In A Patient With Late Stage Dementia (Assessed With Type 3 Diabetes) A Potential Role Of Neurogenesis
Researchers found that a ketogenic diet and ketone supplements helped eliminate excessive daytime sleepiness in an elderly woman with late-stage dementia, possibly by promoting brain cell repair.
- Heart Health
A Novel Hypothesis For Atherosclerosis As A Cholesterol Sulfate Deficiency Syndrome
Researchers propose that atherosclerosis (artery hardening) may be caused by a deficiency of cholesterol sulfate rather than too much cholesterol itself.
- Evolutionary Health and Aging
A Paleogenomic Reconstruction Of The Deep Populati
Scientists studied ancient DNA from 89 people over 9,000 years to map how populations moved and mixed in the Andes mountains, revealing patterns of genetic stability and migration.
- Mental Health
A Pilot Study Examining A Ketogenic Diet As An Adjunct Therapy To MDD
A 10-week ketogenic diet study in college students with depression found a 69-71% reduction in depressive symptoms alongside weight loss and improved brain function.
- Heart Health
A Platelet Dependent Serum Factor That Stimulates The Proliferation Of Arterial Smooth Muscle Cells In Vitro
Researchers discovered that platelets (blood clotting cells) release a factor that causes arterial wall cells to multiply, which may help explain how atherosclerosis develops.
- Nutrition and Health
A Proposal For A Study On Treatment Selection And Lifestyle Recommendations In Chronic Inflammatory Diseases A Danish Multidisciplinary Collaboration On Prognostic Factors And Personalised Medicine
Danish researchers are proposing a large collaborative study to develop personalized treatment approaches for chronic inflammatory diseases by examining how genetics, lifestyle, and other factors affect treatment outcomes.
- Gut Health
A Prospective Double Blind Placebo Controlled Trial 2007 The American Jour
Researchers found that people with celiac disease can safely consume trace amounts of gluten contamination up to 50 mg daily without significant intestinal damage.
- Gut Health
A Prospective Cohort Analysis Of Gut Microbial Co Metab 2020 The American Jo
Researchers compared gut bacteria and their byproducts in Alaska Native people (who have very high colon cancer rates) versus rural Africans (who have very low rates) to understand how diet and gut health affect cancer risk.
- Heart Health
A Protein Extract From Chicken Reduces Plasma Homocysteine In Rats
A study found that feeding rats a protein extract from chicken lowered their blood levels of homocysteine, a compound linked to heart disease risk.
- Heart Health
A Protein Extract From Chicken Reduces Plasma Homocysteine In Rats
Researchers found that feeding rats a protein extract from chicken significantly lowered their blood levels of homocysteine, a compound linked to heart disease risk.
- Mental Health
A Pyruvate Dehydrogenase Complex Disorder Hypothesis For Bipolar Disorder
Researchers propose that bipolar disorder may be caused by problems with how brain cells process glucose for energy, which could explain why ketogenic diets might help stabilize mood.
- Heart Health
A Randomized Controlled Feeding Trial Based On The D 2018 The American Journ
Following the official U.S. Dietary Guidelines for 8 weeks lowered blood pressure but didn't improve blood sugar control or cholesterol levels compared to a typical American diet.
- Nutrition and Health
A Recent Overview Of Producers And Important Dietary Sources Of Aflatoxins
This research review identifies the main sources of aflatoxins - dangerous natural toxins that contaminate common foods like nuts, grains, and spices, posing ongoing health risks.
- Environment and Health
A Review Of Fatty Acid Profiles And Antioxidant Content In Grass Fed And Grain Fed Beef
Grass-fed beef contains healthier fats, more antioxidants, and beneficial nutrients compared to grain-fed beef, though it has a different taste and appearance.
- Mental Health
A Review Of The Biochemistry, Metabolism And Clinical Benefits Of Thiamin(e) And Its Derivatives
Vitamin B1 (thiamine) is essential for processing glucose, and eating too much sugar or refined carbs can create a deficiency that causes concerning symptoms.
- Heart Health
A Review Of The Evidence Of Total Dietary Fat On Vascular Function
This review examined how different types of dietary fats affect blood vessel health, finding that high-fat meals impair vascular function but evidence for which specific fats are best remains unclear.
- Nutrition and Health
A Review Of The Science Of Colorful, Plant Based Food And Practical Strategies For “Eating The Rainbow”
This research review explains how eating colorful fruits and vegetables provides powerful plant compounds called phytonutrients that protect against chronic diseases like heart disease, diabetes, and cancer.
- Environment and Health
A Review Of Transformative Strategies For Climate Mitigation By Grasslands
This research review examines how grassland ecosystems can help combat climate change through carbon storage and other environmental strategies.
- Evolutionary Health and Aging
A Role For Suppressed Incisor Cuspal Morphogenesis In The Evolution Of Mammalian Heterodont Dentition
Scientists discovered how mammalian teeth evolved their different shapes by studying a gene that controls whether teeth develop as simple incisors or complex molars with multiple cusps.
- Environment and Health
A Social Cost Benefit Analysis Of Meat Taxation And A Fruit And Vegetables Subsidy For A Healthy And Sustainable Food Consumption In The Netherlands
Dutch researchers found that taxing meat and subsidizing fruits and vegetables would benefit society through improved health, reduced healthcare costs, and environmental protection over 30 years.
- Heart Health
A Standard Lipid Panel Is Insufficient For The Care Of A Patient On A High Fat, Low Carbohydrate Ketogenic Diet
Standard cholesterol tests may not accurately assess heart health risks for people following ketogenic diets, requiring more detailed lipid analysis.
- Evolutionary Health and Aging
A Study Of The Blood Lipoids And Blood Protein In Canadian Eastern Arctic Eskimos
This 1937 study examined blood fats and proteins in Canadian Arctic Inuit people to understand how their traditional high-fat diet affected their metabolism.
- Evolutionary Health and Aging
A Unique Hominin Menu Dated To 1.95 Million Years Ago
Scientists discovered that our early human ancestors ate a diverse diet including fish, turtles, and small animals 1.95 million years ago, not just large mammals.
- Evolutionary Health and Aging
A Unique Hominin Menu Dated To 1.95 Million Years Ago Copy
New archaeological evidence shows our human ancestors 1.95 million years ago ate a surprisingly diverse diet including fish, turtles, and other aquatic animals, not just large land mammals.
- Heart Health
A Very Low Fat Diet Is Not Associated With Improved Li 1999 The American Jou
Very low-fat diets (10% fat) don't improve cholesterol levels better than moderate low-fat diets and may actually worsen heart health markers in some men.
- Heart Health
A Western Type Diet Attenuates Pulmonary Hypertension Wit 2011 The Journal O
A study in rats found that a Western-style high-fat, high-sugar diet unexpectedly helped protect against severe heart failure and weight loss, challenging common assumptions about diet and heart health.
- Environment and Health
A Worksite Programme Significantly Alters Nutrient Intakes
A workplace program teaching employees to follow a plant-based, low-fat diet successfully improved their nutritional intake by reducing harmful fats and increasing protective nutrients.
- Gut Health
A Zero Carbohydrate Carnivore Diet Can Normalize H
A small study found that following a meat-only diet for 2-6 weeks helped normalize breath tests indicating small intestinal bacterial overgrowth (SIBO) in most patients.
- Gut Health
A Zero Carbohydrate, Carnivore Diet Can Normalize Hydrogen Positive Small Intestinal Bacterial Overgrowth Lactulose Breath Tests A Case Report
A small study found that eating only animal products (meat, fat, no carbs) for 2-6 weeks eliminated small intestinal bacterial overgrowth (SIBO) in most patients tested.
- Dental Health
Abnormal Micronutrient Intake Is Associated With The Risk Of Periodontitis A Dose–response Association Study Based On NHANES 2009–2014
This study found that both too little and too much of certain vitamins and minerals can increase your risk of gum disease (periodontitis).
- Joint, Muscle Health and Exercise
Abnormal Properties Of Collagen Lysyl Hydroxylase From Skin Fibroblasts Of Siblings With Hydroxylysine Deficient Collagen
Researchers studied two siblings with a rare genetic condition called Ehlers-Danlos syndrome and found their cells couldn't properly produce a key enzyme needed for healthy collagen formation.
- Evolutionary Health and Aging
About Gladiators And A Sacred Disease
This journal issue explores various cutting-edge medical treatments including the ketogenic diet for epilepsy and gut microbiome transplants for brain health.
- Nutrition and Health
Absorption Distribution And Excretion Of Selenium From B 2003 The Journal O
This study tracked how the body absorbs and uses selenium from foods like beef and rice, finding that selenium from food behaves differently than selenium supplements.
- Heart Health
ACC AHA ESC 2006 Guidelines For The Management Of Patients With 2006 Journa
Major medical organizations released comprehensive guidelines in 2006 for doctors on how to diagnose and treat atrial fibrillation, a common heart rhythm disorder.
- Hormone Health
Acceleration Of BMI In Early Childhood And Risk Of Sustained Obesity
Children who experience rapid weight gain between ages 2-6 are much more likely to remain overweight or obese as teenagers.
- Nutrition and Health
Acetone As Biomarker For Ketosis Buildup Capability A Study In Healthy Individuals Under Combined High Fat And Starvation Diets
This study found that eating high-fat diets before fasting significantly increases ketone production, with people who have higher metabolism and lower BMI producing more ketones.
- Environment and Health
Acute Nutritional Ketosis And Its Implications For Plasma Glucose And Glucoregulatory Peptides In Adults With Prediabetes A Crossover Placebo Controlled Randomized Trial
Researchers found that a ketone supplement drink quickly lowered blood sugar levels in people with prediabetes, suggesting potential benefits for preventing type 2 diabetes.
- Liver and Kidney Health
Acute Oxalate Nephropathy Caused By Excessive Vegetable Juicing And Concomitant Volume Depletion
A 68-year-old man developed severe kidney failure requiring permanent dialysis after drinking large amounts of spinach-based vegetable juice daily for six months.
- Environment and Health
Acute Satiety Response Of Mammalian, Avian And Fish Proteins In Dogs
Researchers tested whether different animal proteins (fish, chicken, beef, pork) affect hunger and satiety differently in dogs, finding no significant differences between protein sources.
- Mental Health
Acutely Increased β Hydroxybutyrate Plays A Role In The Prefrontal Cortex To Escape Stressful Conditions During The Acute Stress Response
Researchers found that beta-hydroxybutyrate (a ketone produced during fasting or low-carb eating) increases in the brain during stress and may help improve our ability to cope with stressful situations.
- Nutrition and Health
Acyl Coenzyme A Thioesterase 9 Traffics Mitochondrial Short Chain Fatty Acids Toward De Novo Lipogenesis And Glucose Production In The Liver
Researchers discovered that a specific liver enzyme called Acot9 promotes fat accumulation and excess glucose production, making it a potential target for treating fatty liver disease.
- Environment and Health
Adaptive Multi Paddock Grazing Enhances Soil Carbon And Nitrogen Stocks And Stabilization Through Mineral Association In Southeastern U.S. Grazing Lands
A regenerative cattle grazing method called adaptive multi-paddock grazing helps soil store more carbon and nitrogen, which could benefit climate and potentially improve the nutritional quality of grass-fed foods.
- Environment and Health
Adaptive Multi Paddock Grazing Enhances Soil Carbon And Nitrogen Stocks And Stabilization1 Through Mineral Association In Southeastern U.S. Grazing Lands
A sustainable cattle grazing method called adaptive multi-paddock grazing stores more carbon in soil than conventional grazing, potentially helping fight climate change.
- Environment and Health
Adaptive Multi Paddock Grazing Management’s Influence On Soil Food Web Community Structure For Increasing Pasture Forage Production, Soil Organic Carbon, And Reducing Soil Respiration Rates In Southeastern USA Ranches
A study found that rotational grazing methods produce healthier soil with more carbon storage and better grass growth compared to continuous grazing.
- Dental Health
Added Sugars And Cardiovascular Disease Risk In Children A Scientific Statement From The American Heart Association
The American Heart Association found that added sugars significantly increase heart disease risk factors in children, even at levels much lower than what most kids currently consume.
- Gut Health
Addition Of Prebiotics To The Ketogenic Diet Improves Metabolic Profile But Does Not Affect Seizures In A Rodent Model Of Infantile Spasms Syndrome
Adding prebiotics to the ketogenic diet improved metabolic health markers in young animals with seizures, though it didn't reduce the seizures themselves.
Disclaimer: this library, including every summary, is for general informational and educational purposes only. It does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before changing your diet, exercise, or health regimen, or if you have questions about a medical condition.