Metabolic
Library
1,810 peer-reviewed papers, each with a plain-language summary and the source document. The evidence behind the VALIA method, kept where you can read it.
Educational information only. Not medical advice, diagnosis or treatment. For anything about your own health, speak with a clinician. To become a patient, start at our contact page.
1,810 papers
· 13 topics
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1,810 results · page 27 of 38
- Nutrition and Health
Opposing Effects Of Fasting Metabolism On Tissue Tolerance In Bacterial And Viral Inflammation
This study found that fasting helps your body fight bacterial infections but hurts your ability to fight viral infections like the flu.
- Brain and Nerve Health
Optimal Clinical Management Of Children Receiving Dietary Therapies For Epilepsy Updated Recommendations Of The International Ketogenic Diet Study Group
Medical experts updated their guidelines for using ketogenic and other special diets to treat children with hard-to-control epilepsy.
- Nutrition and Health
Optimal Nutritional Status For A Well Functioning Immune System Is An Important Factor To Protect Against Viral Infections
Proper nutrition with key vitamins, minerals, and omega-3 fatty acids helps strengthen your immune system to better fight off viral infections like flu and COVID-19.
- Liver and Kidney Health
Oral AGE Restriction Ameliorates Insulin Resistance In Obese Individuals With The Metabolic Syndrome A Randomised Controlled Trial
A year-long study found that eating foods low in harmful compounds called AGEs significantly improved insulin sensitivity in obese people with metabolic syndrome.
- Heart Health
Oreo Cookie Lowers LDL
A single person with high cholesterol on a ketogenic diet found that eating 12 Oreo cookies daily lowered their cholesterol more effectively than prescription statin medication.
- Heart Health
Oreo Cookie Treatment Lowers LDL Cholesterol More Than High Intensity Statin Therapy In A Lean Mass Hyper Responder On A Ketogenic Diet A Curious Crossover Experiment
A single-person study found that eating Oreo cookies lowered LDL ("bad") cholesterol more effectively than statin medication in someone following a ketogenic diet.
- Nutrition and Health
Organic Acid, A Virulence Factor For Pathogenic Fungi, Causing Postharvest Decay In Fruits
Research shows that harmful fungi cause fruit to rot by producing organic acids that make the fruit's environment more acidic, helping the fungi infect and spread.
- Joint, Muscle Health and Exercise
Organization Of Dietary Control For Nutrition Training Intervention Involving Periodized Carbohydrate Availability And Ketogenic Low Carbohydrate High Fat Diet
Researchers successfully implemented three different dietary approaches in elite athletes, showing that high-carbohydrate, flexible carbohydrate timing, and ketogenic diets can all be practically managed with proper planning.
- Mental Health
Orthorexia Nervosa And Eating Disorder Symptoms In Dietitians In The United States
A study of registered dietitians found higher rates of orthorexia (obsession with "healthy" eating) and eating disorders compared to the general population.
- Heart Health
OSA And CV Dz
A large genetic study found that obstructive sleep apnea (OSA) may directly cause heart failure, providing strong evidence that sleep breathing problems seriously threaten heart health.
- Brain and Nerve Health
Outcomes Of Dietary Interventions In The Prevention And Progression Of Parkinson S Disease A Literature Review
This review examined how different diets like Mediterranean, ketogenic, and plant-based eating patterns might help prevent or slow the progression of Parkinson's disease.
- Hormone Health
Ovulation Rates And Embryo Degeneracy In Female Mice Fed The Phytoestrogen, Coumestrol
This 1981 study found that coumestrol, a plant compound found in many common foods, significantly reduced fertility and increased embryo problems in female mice.
- Liver and Kidney Health
Oxalic Acid Exemption From The Requirement Of A Tolerance
The EPA ruled that oxalic acid residues on honey and honeycomb don't require safety limits, meaning these levels are considered safe for consumption.
- Liver and Kidney Health
Oxidative Stress, Aging, And Diseases
This research explains how oxidative stress - an imbalance between harmful molecules and protective antioxidants - contributes to aging and many chronic diseases.
- Heart Health
Oxidized Low Density Lipoprotein Regulates Matrix Metalloproteinase 9 And Its Tissue Inhibitor In Human Monocyte Derived Macrophages
This study found that oxidized "bad" cholesterol triggers immune cells to produce enzymes that can weaken artery walls and make heart attacks more likely.
- Gut Health
Palmitoylethanolamide And Polydatin In Pediatric Irritable Bowel S 2024 Nutr
A natural supplement combination (palmitoylethanolamide and polydatin) significantly reduced irritable bowel syndrome symptoms in children compared to placebo over 12 weeks.
- Joint, Muscle Health and Exercise
Paradox Of Hypercholesterolaemia In Highly Trained, Keto Adapted Athletes
Elite endurance athletes following a ketogenic diet for over a year showed dramatically higher cholesterol levels, but with signs suggesting lower heart disease risk.
- Brain and Nerve Health
Parkinson Disease And The Microbiome Natural Medicine Journal
Research shows that gut bacteria may play a key role in Parkinson's disease development, as digestive symptoms often appear decades before movement problems begin.
- Hormone Health
Past And Future Corollaries Of Theories On Causes Of Metabolic Syndrome And Obesity Related Co Morbidities Part 2 A Composite Unifying Theory Review Of Human Specific Co Adaptations To Brain Energy Consumption
This research proposes that metabolic syndrome and obesity developed because our large, energy-hungry brains evolved systems that both crave high-calorie foods and efficiently use protective plant nutrients.
- Environment and Health
Pasture Cattle
Research comparing pasture-raised versus grain-fed beef found that grass-fed cattle had three times more vitamin E (alpha-tocopherol), while grain-fed beef contained much higher levels of a different form of vitamin E.
- Environment and Health
Pasture Finishing Of Bison Improves Animal Metabolic Health And Potential Health Promoting Compounds In Meat
Bison that grazed on pasture instead of eating corn and hay in pens had healthier metabolism and produced meat with more beneficial nutrients.
- Heart Health
Pathogenesis Of Atherosclerosis
This research explains how atherosclerosis (artery-hardening disease) develops when the protective inner lining of blood vessels gets damaged, leading to cardiovascular disease.
- Hormone Health
Pathogenesis Of Obesity
Scientists are debating two main theories about what causes obesity - whether it's simply eating too much versus hormonal changes from certain foods like carbohydrates.
- Hormone Health
Pathogenesis Of Obesity(1)
Researchers are debating whether obesity is caused simply by eating too much versus a more complex process involving hormones like insulin that may drive overeating.
- Gut Health
Pathological Implications Of Receptor For Advanced Glycation End Product (AGER) Gene Polymorphism
Genetic variations in the AGER gene may influence your risk of developing diabetes complications, heart disease, cancer, and inflammatory conditions.
- Evolutionary Health and Aging
People Have Shaped Most Of Terrestrial Nature For At Least 12,000 Years
Research shows that humans have been actively shaping and managing natural environments worldwide for at least 12,000 years, much longer than previously thought.
- Liver and Kidney Health
Peripheral Arterial Calcification Prevalence, Mechanism, Detection, And Clinical Implications
Calcium buildup in arteries is common in people with diabetes and kidney disease, making blood vessels stiff and increasing heart disease risk.
- Heart Health
Perivascular Adipocytes Are Components Of Adventitia Vascular “Kuiper Belt”
Researchers discovered that fat tissue around blood vessels acts like a protective "belt" but becomes problematic and forms scar tissue when arteries develop atherosclerosis.
- Evolutionary Health and Aging
Persistent Epigenetic Differences Associated With Prenatal Exposure To Famine In Humans
Researchers found that people exposed to severe malnutrition before birth had lasting genetic changes that persisted 60 years later, showing how early nutrition can permanently affect our genes.
- Liver and Kidney Health
Persistent Fasting Lipogenesis Links Impaired Ketogenesis With Citrate Synthesis In Humans With Nonalcoholic Fatty Liver
Researchers found that people with fatty liver disease continue producing fat even while fasting, which disrupts the liver's normal ability to burn fat and produce ketones for energy.
- Faith and Health
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Religious fasting practices like Ramadan and Orthodox Christian fasting may reduce some heart disease risk factors including body weight, blood pressure, and cholesterol levels.
- Heart Health
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CaRi-Heart is a new software tool that analyzes CT heart scans to measure inflammation in coronary arteries and predict 8-year heart attack risk.
- Joint, Muscle Health and Exercise
Physical Activity Is Associated With Reduced Risk
A large UK study found that people who walked more had significantly lower risks of developing liver disease, with just 2,500 extra steps per day reducing liver disease risk by 38%.
- Joint, Muscle Health and Exercise
Physical Activity Is Associated With Reduced Risk (1)
A large UK study found that people who walked more had significantly lower risks of developing liver disease, with just 2,500 extra daily steps reducing liver disease risk by 38%.
- Mental Health
Physical Complaints Decrease After Following A Few Foods Diet In Children With ADHD
A restrictive "few-foods diet" reduced both ADHD symptoms and physical complaints like digestive issues, skin problems, and sleep troubles in children.
- Mental Health
Physical Exercise For Treatment Of Mood Disorders
This research review examined how physical exercise can be used as a treatment for mood disorders like depression and anxiety.
- Mental Health
Physical Exercise For Treatment Of Mood Disorders A Critical Review
This research review examines how physical exercise can be used as a treatment for mood disorders like depression and anxiety.
- Heart Health
Physical Principles Of Vascular Developing And Remodeling
Researchers propose that blood vessels develop and change throughout life following physical principles similar to how planets form, which could help explain heart disease development.
- Joint, Muscle Health and Exercise
Physical Remodeling Of Connective Tissues
This research examines how the body's connective tissues - including muscles, tendons, bones, and blood vessels - naturally rebuild and adapt themselves in response to physical stress and activity.
- Joint, Muscle Health and Exercise
Physical Remodeling Of Connective Tissues(1)
This research explains how connective tissues like blood vessels, heart muscle, skeletal muscle, cartilage and bone naturally remodel and change structure throughout adult life in response to physical forces.
- Nutrition and Health
Physiologic Adaptation To Macronutrient Change Distorts Findings From Short Dietary Trials Reanalysis Of A Metabolic Ward Study
This study found that short-term diet research can be misleading because our bodies need time to fully adapt when switching between low-carb and low-fat eating patterns.
- Joint, Muscle Health and Exercise
Physiological Impact Of A Single Serving Slow Absorption Carbohydrate On Metabolic, Hemodynamic, And Performance Markers In Endurance Athletes During A Bout Of Exercise
Slow-absorbing carbohydrates help endurance athletes burn more fat during long runs while maintaining steady blood sugar levels compared to fast-absorbing carbs.
- Joint, Muscle Health and Exercise
Physiological Impact Of A Single Serving Slow Absorption Carbohydrate On Metabolic, Hemodynamic, And Performance Markers In Endurance Athletes During A Bout Of Exercise(1)
Slow-absorbing carbohydrates help endurance athletes burn more fat during exercise while maintaining steady blood sugar compared to fast-absorbing carbohydrates.
- Nutrition and Health
Phytochemicals, Nutrition, Metabolism, Bioavailability, And Health Benefits In Lettuce—A Comprehensive Review
This comprehensive review examines lettuce's nutritional compounds and health benefits, showing how this common leafy green provides antioxidants and nutrients that support overall health.
- Heart Health
Phytosterols, Phytostanols, And Lipoprotein Metabolism
Plant compounds called phytosterols and phytostanols can lower "bad" LDL cholesterol by 8-10% when taken daily, offering a natural way to support heart health.
- Liver and Kidney Health
PIEZO1 Ion Channel Mediates Ionizing Radiation Induced Pulmonary Endothelial Cell Ferroptosis Via Ca2+ Calpain VE Cadherin Signaling
Researchers discovered how radiation damages lung blood vessels through a specific cellular death process, potentially leading to new treatments for radiation-induced lung injury.
- Brain and Nerve Health
Pilot Study Of A Ketogenic Diet In Relapsing Remitting MS
A small study found that people with multiple sclerosis who followed a modified ketogenic diet for six months experienced reduced fatigue and depression along with weight loss.
- Nutrition and Health
PKM2 Promotes Reductive Glutamine Metabolism
Researchers discovered how a specific enzyme called PKM2 helps cancer cells rewire their metabolism to use glutamine (an amino acid) as fuel when glucose is limited.
Disclaimer: this library, including every summary, is for general informational and educational purposes only. It does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before changing your diet, exercise, or health regimen, or if you have questions about a medical condition.