Metabolic
Library
1,810 peer-reviewed papers, each with a plain-language summary and the source document. The evidence behind the VALIA method, kept where you can read it.
Educational information only. Not medical advice, diagnosis or treatment. For anything about your own health, speak with a clinician. To become a patient, start at our contact page.
1,810 papers
· 13 topics
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1,810 results · page 29 of 38
- Heart Health
Progress In Understanding The LDL Receptor And HMG CoA Reductase, Two Membrane Proteins That Regulate The Plasma Cholesterol Copy
Scientists discovered how two key proteins work together to control cholesterol levels in the blood, which helps explain how the body prevents heart disease.
- Heart Health
Progress, Prospects And Provender Chairman S Address Before The Council On Arteriosclerosis, American Heart Association Dallas, Texas, November 12, 1969
This 1969 address reflects on 25 years of heart disease research progress, showing how atherosclerosis went from being seen as inevitable aging to a treatable condition.
- Evolutionary Health and Aging
Prolonging Healthy Aging Longevity Vitamins And Proteins
A nutrition researcher proposes that certain vitamins and nutrients are essential not just for basic survival, but specifically for healthy aging and preventing age-related diseases.
- Nutrition and Health
Prominent Action Of Butyrate Over β Hydroxybutyrate As Histone Deacetylase Inhibitor, Transcriptional Modulator And Anti Inflammatory Molecule
Researchers found that butyrate (produced by gut bacteria) is more effective than ketones at reducing inflammation and regulating genes that affect health.
- Brain and Nerve Health
Prospective Control Study Of Efficacy And Influencing Factors Of A Ketogenic Diet On Refractory Epilepsy In Children(1)
A ketogenic diet combined with seizure medications was more effective than medications alone for treating hard-to-control epilepsy in children.
- Liver and Kidney Health
Protection Of Hippocampal Neurons From Ischemia Induced Delayed Neuronal Death By Hepatocyte Growth Factor A Novel Neurotrophic Factor
Researchers found that hepatocyte growth factor (HGF), a protein that helps organs heal, can protect brain cells from damage after stroke-like conditions.
- Evolutionary Health and Aging
Protective Effects Of Alpha Lipoic Acid (ALA) Are Mediated By Hormetic Mechanisms
Alpha lipoic acid (ALA) supplements provide protective health benefits through a "hormesis" mechanism, where small amounts of cellular stress trigger the body's natural defense systems.
- Nutrition and Health
Protective Effects Of Dietary Carnosine During In Vitro Digestion Of Pork Differing In Fat Content And Cooking Conditions
Researchers found that carnosine, a natural compound in meat, may protect against harmful molecules that form during digestion of pork, potentially reducing health risks associated with red meat consumption.
- Mental Health
Protein Energy Supplementation In Early Life Decreases The 2022 The Journal
A study in Guatemala found that children who received protein and energy supplements during their first 1000 days of life had significantly lower rates of mental distress as adults.
- Liver and Kidney Health
Protein Enriched Diet, With The Use Of Lean Red Meat, Combined With Progressive Resistance Training Enhances Lean Tissue Mass And Muscle Strength And Reduces Circulating IL 6 Concentrations In Elderly Women A Cluster Randomized Controlled Trial
A study found that elderly women who combined resistance training with eating lean red meat gained more muscle mass and strength while reducing inflammation compared to those doing resistance training alone.
- Joint, Muscle Health and Exercise
Protein Ingestion Limit
Researchers found that eating large amounts of protein (100g) after exercise continues building muscle for over 12 hours, with no upper limit to the muscle-building benefits.
- Nutrition and Health
Protein Intake Trends And Conformity With The Dietary Ref 2018 The American
Most Americans get enough protein in their diets, but teenage girls and older Black men are most likely to fall short of recommended amounts.
- Nutrition and Health
Protein Quantity And Source Fasting Mimicking Diets 2019 Advances In Nutr
Restricting protein intake and using periodic fasting-mimicking diets may help promote longevity and prevent age-related diseases like cancer and diabetes.
- Joint, Muscle Health and Exercise
Protein, Iron, And Meat Consumption And Risk For Rheumatoid Arthritis A Prospective Cohort Study
A large study of over 82,000 women found that eating more protein, iron, or meat did not increase the risk of developing rheumatoid arthritis.
- Joint, Muscle Health and Exercise
Protein, Iron, And Meat Consumption And Risk For Rheumatoid Arthritis A Prospective Cohort Study (1)
A large 22-year study of over 82,000 women found no link between protein, iron, or meat consumption and developing rheumatoid arthritis.
- Nutrition and Health
Prurigo Pigmentosa A Report Of Two Patients In Possible Association With Essential Fatty Acid Deficiency Prurigo
Two young men developed an itchy rash called prurigo pigmentosa while following very low-carb, low-fat diets, which may have caused essential fatty acid deficiency.
- Heart Health
Psychological Stress And CVD
Research shows that psychological stress increases the risk of heart disease, likely through increased inflammation in the body.
- Heart Health
Psychological Stress, Inflammation, CAD
This research review found that psychological stress is an independent risk factor for heart disease, likely working through increased inflammation in the body.
- Joint, Muscle Health and Exercise
Quality Of Life Of Female And Male Vegetarian And Vegan Endurance Runners Compared To Omnivores – Results From The NURMI Study
A study of 281 endurance runners found that both plant-based and omnivorous diets can support high quality of life, with some differences between men and women.
- Joint, Muscle Health and Exercise
Quality Of Life Of Female And Male Vegetarian And Vegan Endurance Runners Compared To Omnivores – Results From The NURMI Study(1)
A study of endurance runners found that vegetarian and vegan athletes reported similar quality of life scores compared to those eating meat-based diets.
- Nutrition and Health
Quantitative Fluxomics Of Circulating Metabolites
Researchers used advanced tracking methods to discover how the body converts different nutrients into energy, finding that our internal metabolism remains remarkably stable regardless of whether we eat high-carb or ketogenic diets.
- Nutrition and Health
RAGE The Beneficial And Deleterious Effects By Diverse Mechanisms Of Actions
RAGE is a cellular receptor that can either help or harm the body by triggering inflammation and stress responses, potentially contributing to diabetes, heart disease, and brain disorders.
- Heart Health
Randomised Trial Of Coconut Oil, Olive Oil Or Butter On Blood Lipids And Other Cardiovascular Risk Factors In Healthy Men And Women
This study compared how eating coconut oil, olive oil, or butter daily for four weeks affected cholesterol levels and heart health markers in healthy adults.
- Liver and Kidney Health
Randomized Clinical Trial To Evaluate The Morphological Changes In The Adventitial Vasa Vasorum Density And Biological Markers Of Endothelial Dysfunction In Subjects With Moderate Obesity Undergoing A Very Low Calorie Ketogenic Diet
A ketogenic very low-calorie diet improved blood vessel health markers and reduced cardiovascular risk factors better than a standard Mediterranean diet in people with moderate obesity.
- Hormone Health
Randomized Trial Of LCD For Obesity
A year-long study found that low-carb diets helped people lose more weight than conventional low-fat diets in the first six months, but the advantage disappeared by one year.
- Hormone Health
Randomized Trial Of LCD For Obesity(1)
A year-long study found that low-carb diets led to more weight loss than traditional low-fat diets in the first six months, but the difference disappeared by one year.
- Heart Health
Re Eval DIet Heart Hypothesis
This study re-examined data from a 1970s experiment and found that replacing saturated fats with vegetable oils didn't reduce heart disease deaths, despite lowering cholesterol levels.
- Heart Health
Re Evaluation Of The Traditional Diet Heart Hypothesis Analysis Of Recovered Data From Minnesota Coronary Experiment (1968 73)
This study reanalyzed data from a 1970s experiment that found replacing saturated fats with vegetable oils lowered cholesterol but didn't reduce heart disease deaths as expected.
- Joint, Muscle Health and Exercise
Re Examining High Fat Diets For Sports Performance Did We Call The ‘Nail In The Coffin’ Too Soon
This research review found that while high-fat, low-carb diets help muscles burn fat better during exercise, they don't clearly improve athletic performance and may hurt high-intensity efforts.
- Nutrition and Health
Reaction Of Lectin Specific Antibody With Human Tissue Possible Contributions To Autoimmunity
This study found that antibodies against plant proteins called lectins can mistakenly attack human tissues, potentially contributing to autoimmune diseases.
- Environment and Health
Recent Fast Food Consumption And Bisphenol A And Phthalates Exposures Among The U.S. Population In NHANES, 2003–2010
This study examined how eating fast food increases exposure to harmful chemicals called phthalates and BPA that may disrupt hormones and affect metabolic health.
- Heart Health
Recent Insights Into The Cellular Biology Of Atherosclerosis
This research explains how atherosclerosis (artery-clogging plaque) develops when cholesterol-carrying particles get trapped in artery walls, triggering inflammation that can lead to heart attacks and strokes.
- Nutrition and Health
Recommended Dietary Reference Intakes, Nutritional Goals And Dietary Guidelines For Fat And Fatty Acids A Systematic Review
This study reviewed dietary fat recommendations from different countries and health organizations, finding similar advice on total fat intake but gaps in research-based evidence.
- Liver and Kidney Health
Recurrent Acute Pancreatitis During A Ketogenic Diet—a Case Report And Literature Review
A 35-year-old man developed recurring pancreas inflammation (pancreatitis) while following a ketogenic diet, with episodes triggered by weekend "cheat days."
- Nutrition and Health
Red And Processed Meat More With 2020 The American Journal Of Clinical Nut
This research review examines the evidence behind dietary guidelines recommending reduced red and processed meat consumption as part of healthy eating patterns that prevent chronic diseases.
- Heart Health
Red And Processed Meat Intakes And Cardiovascular Disease And Type 2 Diabetes Mellitus An Umbrella Systematic Review And Assessment Of Causal Relations Using Bradford Hill’s Criteria
This comprehensive research review found that eating processed meats increases the risk of developing type 2 diabetes, while the connection between red meat and heart disease remains unclear.
- Heart Health
Red Meat And CV Risk
A large genetic study found no causal link between eating red meat or processed meat and increased risk of heart disease, stroke, or heart failure.
- Heart Health
Red Meat Consumption And Risk For Dyslipidaemia And Inflammation A Systematic Review And Meta Analysis
This research review found that eating red meat increases harmful cholesterol levels and inflammation markers compared to eating white meat or plant-based proteins.
- Mental Health
Reduced Anxiety In Forensic Inpatients After A Long Term Intervention With Atlantic Salmon
A 23-week study found that eating Atlantic salmon three times per week significantly reduced anxiety and improved heart health markers in male participants.
- Gut Health
Reduced Dietary Intake Of Carbohydrates By Obese Subjects Results In Decreased Concentrations Of Butyrate And Butyrate Producing Bacteria In Feces
Low-carb diets reduced beneficial gut bacteria that produce butyrate, a compound important for colon health, in obese adults over four weeks.
- Nutrition and Health
Reduced Pain And Inflammation In Juvenile And Adult Rats Fed A Ketogenic Diet
A study in rats found that following a ketogenic diet (very high fat, very low carb) significantly reduced both pain sensitivity and inflammation compared to a standard diet.
- Environment and Health
Reducing Vulnerability Of Rainfed Agriculture Through Seasonal 2018 Agricult
Researchers developed better weather prediction methods to help rice farmers adapt to climate change and maintain stable food production.
- Heart Health
Reduction In Saturated Fat Intake For Cardiovascular Disease
This comprehensive review examined whether reducing saturated fat intake helps prevent heart disease and cardiovascular events.
- Liver and Kidney Health
Reduction Of Cardio Metabolic Risk And Body Weight Through A Multiphasic Very Low Calorie Ketogenic Diet Program In Women With Overweight Obesity A Study In A Real World Setting
A structured very-low-calorie ketogenic diet program helped overweight women lose significant weight and improve heart health markers over 24 weeks.
- Nutrition and Health
Reductions In Portion Size And Energy Density Of Foo 2006 The American Journ
Eating smaller portions and choosing foods with fewer calories per bite both help reduce daily calorie intake without making you feel hungrier.
- Gut Health
Reframing Nutritional Microbiota Studies To Reflect An Inherent Metabolic Flexibility Of The Human Gut A Narrative Review Focusing On High Fat Diets
This review challenges the common belief that high-fat diets harm gut health, suggesting that well-designed high-fat diets may actually support a healthy, adaptable gut microbiome.
- Skin and Hair Health
Relationship Between Bullous Pemphigoid And Metabolic Syndrome
A 12-year study found that people with bullous pemphigoid (a blistering skin condition) are more than twice as likely to have metabolic syndrome.
- Brain and Nerve Health
Relationship Between Glycemic Control And Cognitive Impairment A Systematic Review And Meta Analysis
This research review found that controlling blood sugar levels in people with diabetes helps slow down cognitive decline and protects brain function.
Disclaimer: this library, including every summary, is for general informational and educational purposes only. It does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before changing your diet, exercise, or health regimen, or if you have questions about a medical condition.