Metabolic
Library
1,810 peer-reviewed papers, each with a plain-language summary and the source document. The evidence behind the VALIA method, kept where you can read it.
Educational information only. Not medical advice, diagnosis or treatment. For anything about your own health, speak with a clinician. To become a patient, start at our contact page.
1,810 papers
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1,810 results · page 31 of 38
- Environment and Health
Safety Of EPG
This research reviews the safety of EPG, a modified fat substitute that looks and acts like regular fat but passes through the body without being digested or absorbed.
- Nutrition and Health
Safety Of Soya Based Infant Formulas In Children
A comprehensive review of studies found that soy-based infant formulas are as safe as cow's milk formulas for babies who need them, supporting normal growth and development.
- Joint, Muscle Health and Exercise
Salicin Inhibits AGE Induced Degradation Of Type II Collagen And Aggrecan In Human SW1353 Chondrocytes Therapeutic Potential In Osteoarthritis
Salicin, a natural compound found in willow bark and related to aspirin, may help protect joint cartilage from age-related damage that leads to osteoarthritis.
- Joint, Muscle Health and Exercise
Salicin Inhibits AGE Induced Degradation Of Type II Collagen And Aggrecan In Human SW1353 Chondrocytes Therapeutic Potential In Osteoarthritis(1)
Researchers found that salicin, a natural compound from willow bark, may help protect joint cartilage from age-related damage that leads to osteoarthritis.
- Nutrition and Health
Salt Promotes Passive Overconsumption Of Dietary Fat 2016 The Journal Of Nut
Adding salt to high-fat foods causes people to eat 11% more calories, potentially overriding the body's natural ability to feel full from fatty foods.
- Heart Health
Salt Responsive Metabolite, β Hydroxybutyrate, Att
Researchers found that high-salt diets lower a beneficial ketone called beta-hydroxybutyrate, and supplementing with its precursor can help reduce blood pressure.
- Heart Health
Salt Responsive Metabolite, β Hydroxybutyrate, Attenuates Hypertension
Researchers found that high salt intake lowers a beneficial compound called beta-hydroxybutyrate, and supplementing it through diet may help reduce blood pressure.
- Heart Health
Saturated And Unsaturated Dietary Fats And Cardiometabolic Risk In The Framingham Offspring Study
A large 18-year study found that eating saturated fats did not increase heart disease or diabetes risk, and may actually support better metabolic health.
- Heart Health
Saturated Fat And Health
New research challenges long-standing advice to limit saturated fat, finding that foods like whole dairy and unprocessed meat don't increase heart disease risk as previously thought.
- Mental Health
Schizophrenia, Gluten, And Low Carbohydrate, Ketogenic Diets A Case Report And Review Of The Literature
A 70-year-old woman with severe, lifelong schizophrenia experienced unexpected improvement in her symptoms after starting a low-carbohydrate ketogenic diet.
- Nutrition and Health
Science, Advocacy, And Quackery In Nutritional Books An Analysis Of Conflicting Advice And Purported Claims Of Nutritional Best Sellers
Researchers analyzed the top 100 best-selling nutrition books and found they contain wildly contradictory advice, with many authors lacking proper medical or nutrition credentials.
- Nutrition and Health
Scientific Opinion On The Tolerable Upper Intake Level For Preformed Vitamin A And β‐carotene
European food safety experts confirmed that adults can safely consume up to 3,000 micrograms of vitamin A daily, but recommend avoiding liver products during pregnancy due to birth defect risks.
- Heart Health
Screening For Lipid Disorders In Adults Recommendations And Rationale
The U.S. Preventive Services Task Force strongly recommends cholesterol screening for men starting at age 35 and women at age 45 to prevent heart disease.
- Heart Health
Secular Trends In Risk Profiles Among Adults With CV Disease In The USA
A 20-year study found that Americans with heart disease are getting worse at controlling blood sugar, weight, and blood pressure, though cholesterol management has improved.
- Heart Health
Secular Trends Risk Profiles CVD
A 20-year study found that adults with heart disease got worse at controlling weight, blood sugar, and blood pressure, despite medical advances.
- Joint, Muscle Health and Exercise
Selected In Season Nutritional Strategies To Enhance Recovery For Team Sport Athletes A Practical Overview
This research review identifies specific nutrients and supplements that may help team sport athletes recover faster between training sessions and competitions during their competitive season.
- Joint, Muscle Health and Exercise
Selected In Season Nutritional Strategies To Enhance Recovery For Team Sport Athletes A Practical Overview(1)
This research review identifies specific nutrients and supplements that can help team sport athletes recover faster between training sessions and competitions during their competitive season.
- Nutrition and Health
Selenium And Chronic Diseases A Nutritional Genomics Perspective
Your genes may determine whether selenium supplements help or harm your health, explaining why selenium studies show mixed results.
- Liver and Kidney Health
Selenium Supplementation Alters Hepatic Energy And Fatty Acid Metabolism In Mice
Selenium supplements caused mice to gain more weight by changing how their livers process fats and energy, suggesting supplements may affect metabolism.
- Nutrition and Health
Self Reported Carnivore Diets In Adults
A study of over 2,000 people following a meat-only "carnivore diet" found most reported health improvements and few negative effects, though more research is needed.
- Evolutionary Health and Aging
Sensory Organ Size Evolution A View From Drosophi
Scientists discovered how fruit fly eyes evolve to different sizes by studying genes that control eye development, revealing insights into how organs regulate their size.
- Nutrition and Health
Serum Metabolomic Signatures Of Plant Based Die 2022 The American Journal Of
Researchers found that plant-based diets create unique chemical signatures in the blood that may help protect against chronic kidney disease.
- Environment and Health
Serum Starvation Caveat Emptor
Researchers found that a common laboratory technique called "serum starvation" lacks standardized methods, which may be causing inconsistent and unreliable results across different studies.
- Liver and Kidney Health
Settings Order Article Reprints Open AccessArticle Incidence And Characteristics Of Kidney Stones In Patients On Ketogenic Diet A Systematic Review And Meta Analysis
This research study analyzed multiple studies to determine how often people following ketogenic diets develop kidney stones and what types of stones they get.
- Nutrition and Health
Settings Order Article Reprints Open AccessArticle Meal Timing And Macronutrient Composition Modulate Human Metabolism And Reward Related Drive To Eat
This study found that when you eat and what macronutrients you consume affects both your metabolism and how much you crave rewarding foods throughout the day.
- Heart Health
Settings Order Article Reprints Open AccessArticle Postprandial Lipid Metabolism In Normolipidemic Subjects And Patients With Mild To Moderate Hypertriglyceridemia
Researchers found that meals with medium-chain fats (like coconut oil) cause much smaller spikes in blood triglycerides after eating compared to other types of fats.
- Hormone Health
Settings Order Article Reprints Open AccessArticle Reduction Of Cardio Metabolic Risk And Body Weight Through A Multiphasic Very Low Calorie Ketogenic Diet Program In Women With Overweight Obesity A Study In A Real World Setting
A 24-week very low-calorie ketogenic diet program helped 33 women with overweight/obesity lose significant weight (14.6%) and improve heart health markers safely.
- Joint, Muscle Health and Exercise
Settings Order Article Reprints Open AccessArticle β Hydroxybutyrate Elicits Favorable Mitochondrial Changes In Skeletal Muscle
Researchers found that beta-hydroxybutyrate (a ketone body produced during ketosis) improves the function and health of mitochondria in muscle cells, potentially enhancing muscle performance and reducing cellular damage.
- Heart Health
Settings Order Article Reprints Open AccessArticle β Hydroxybutyrate, A Ketone Body, Potentiates The Antioxidant Defense Via Thioredoxin 1 Upregulation In Cardiomyocytes
Researchers found that beta-hydroxybutyrate (a ketone produced during fasting or ketogenic diets) helps protect heart cells from damage by boosting their natural antioxidant defenses.
- Gut Health
Settings Order Article Reprints Open AccessReview Leaky Gut And Autoimmunity An Intricate Balance In Individuals Health And The Diseased State
This research review explores how "leaky gut" - when the intestinal barrier becomes too permeable - may trigger autoimmune diseases by allowing harmful substances to cross into the bloodstream.
- Joint, Muscle Health and Exercise
Settings Order Article Reprints Open AccessReview Role Of A Ketogenic Diet On Body Composition, Physical Health, Psychosocial Well Being And Sports Performance In Athletes A Scoping Review
This review found that ketogenic diets can help athletes lose body fat and may improve fat burning, but effects on athletic performance are mixed and more research is needed.
- Nutrition and Health
Settings Order Article Reprints Open AccessReview Selenium And Chronic Diseases A Nutritional Genomics Perspective
This research explores how genetic variations affect whether selenium supplements help prevent chronic diseases, explaining why selenium studies show mixed results.
- Heart Health
Severe Clinical Manifestation Of Mitochondrial 3 Hydroxy 3 Methylglutaryl CoA Synthase Deficiency Associated With Two Novel Mutations A Case Report
Researchers report a severe case of a rare genetic condition that prevents the body from properly breaking down fats for energy during illness or fasting.
- Nutrition and Health
Severe Vitamin B12 Deficiency In An Exclusively Breastfed 5 Month Old Italian Infant Born To A Mother Receiving Multivitamin Supplementation During Pregnancy
A 5-month-old breastfed baby developed severe vitamin B12 deficiency and developmental delays despite his vegan mother taking standard multivitamins during pregnancy.
- Heart Health
Sex Difference In Human Mevalonate Metabolism
This study found that women and men process mevalonate (a cholesterol precursor) differently, with women breaking it down faster than men.
- Joint, Muscle Health and Exercise
Sex Differences In Endurance Exercise Capacity And Skeletal Muscle Lipid Metabolism In Mice
Female mice showed 25% better endurance performance than males, likely due to their superior ability to use fat for energy during exercise.
- Joint, Muscle Health and Exercise
Sex Differences In Endurance Exercise Capacity And Skeletal Muscle Lipid Metabolism In Mice(1)
Female mice showed 25% better endurance exercise performance than males, linked to their superior ability to use fats as fuel during exercise.
- Hormone Health
Shaping Fat Distribution New Insights Into The Molecular Determinants Of Depot And Sex Dependent Adipose Biology
Scientists discovered that fat cells in different body areas have unique genetic programming that determines where and how your body stores fat, influenced by sex and hormones.
- Heart Health
Short Chain Fatty Acids Outpace Ketone Oxidation In The Failing Heart
Researchers found that failing hearts can better use short-chain fatty acids (from gut bacteria) than ketones for energy when their normal fat-burning ability is impaired.
- Nutrition and Health
Short Term Glutamine Supplementation Decreases Lung Inflammation And The Receptor For Advanced Glycation End Products Expression In Direct Acute Lung Injury In Mice
Glutamine supplementation reduced lung inflammation in mice with acute lung injury, suggesting this amino acid may help protect against severe respiratory conditions.
- Liver and Kidney Health
Short Term Weight Loss And Hepatic Triglyceride Reduction Evidence Of A Metabolic Advantage With Dietary Carbohydrate Restriction1,2,3
A two-week low-carb diet reduced liver fat more effectively than simply cutting calories, even when both groups lost the same amount of weight.
- Nutrition and Health
Should Dietary Guidelines Recommend Low Red Meat Intake
This research challenges current dietary guidelines that recommend limiting red meat, arguing that the health risks of red meat consumption are not supported by strong scientific evidence.
- Nutrition and Health
Signals Of Energy Availability In Sleep
This research explores how the body's sleep patterns change when burning fat for fuel instead of sugar, which may explain why ketogenic diets benefit both brain and body health.
- Hormone Health
Signals Of Energy Availability In Sleep Consequences Of A Fat Based Metabolism
This research explores how switching from sugar-based to fat-based metabolism (ketosis) affects sleep patterns and energy signaling in the body.
- Evolutionary Health and Aging
Significant Differences In Global Genomic DNA Methylation By Gender And Race Ethnicity In Peripheral Blood
This study found that women and Black individuals have different patterns of DNA chemical modifications that may affect cancer risk, suggesting personalized medicine approaches may be needed.
- Gut Health
Single Cell Transcriptome Analysis Reveals Differential Nutrient Absorption Functions In Human Intestine
Researchers mapped individual cells in the human intestine to understand how different sections absorb nutrients differently, revealing new insights about gut function.
- Skin and Hair Health
Skin Exposure To Sunlight, Microbiome
Researchers found that sunlight exposure may influence the composition of gut bacteria, creating a potential "skin-gut connection" that could affect overall health.
- Skin and Hair Health
Skin Exposure To UVB And Gonadal Axis
UVB light exposure from sunlight triggers hormonal changes that increase sex hormones, enhance romantic feelings, and boost sexual behavior in both mice and humans.
Disclaimer: this library, including every summary, is for general informational and educational purposes only. It does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before changing your diet, exercise, or health regimen, or if you have questions about a medical condition.