Metabolic
Library
1,810 peer-reviewed papers, each with a plain-language summary and the source document. The evidence behind the VALIA method, kept where you can read it.
Educational information only. Not medical advice, diagnosis or treatment. For anything about your own health, speak with a clinician. To become a patient, start at our contact page.
1,810 papers
· 13 topics
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1,810 results · page 33 of 38
- Environment and Health
Taking A Break, 2 Week Social Medial Detox
A two-week social media detox limiting use to 30 minutes daily improved sleep, stress levels, life satisfaction, and reduced smartphone addiction in young adults.
- Liver and Kidney Health
Targeting ASCT2 Mediated Glutamine Uptake Blocks Prostate Cancer Growth And Tumour Development
Researchers found that blocking a protein called ASCT2 that helps prostate cancer cells absorb glutamine (an amino acid) can stop tumor growth and spread.
- Heart Health
Targeting NO
This research review explores how natural compounds like polyphenols can boost nitric oxide production to improve blood vessel health and reduce cardiovascular disease risk.
- Brain and Nerve Health
Targeting Oxidative Stress Improves Disease Outcomes In A Rat Model Of Acquired Epilepsy
Researchers found that two antioxidant supplements (N-acetylcysteine and sulforaphane) given together after brain injury can delay epilepsy onset and reduce seizure frequency in rats.
- Liver and Kidney Health
Targeting The MYCN–PARP–DNA Damage Response Pathway In Neuroendocrine Prostate Cancer
Researchers discovered a new treatment approach for an aggressive form of prostate cancer by targeting specific proteins that help cancer cells repair their DNA damage.
- Heart Health
Tea Flavonoids And Cardiovascular Health 2013 The American Journal Of Cl
This research review explains how drinking tea may protect your heart by improving blood vessel function through natural compounds called flavonoids.
- Nutrition and Health
The 1 Week And 8 Month Effects Of A Ketogenic Diet Or Ketone Salt Supplementation On Multi Organ Markers Of Oxidative Stress And Mitochondrial Function In Rats
This rat study found that following a ketogenic diet for 8 months improved liver function and antioxidant protection, while ketone supplements alone provided fewer benefits.
- Dental Health
THE ACTION OF VITAMIN D IN PREVENTING THE SPREAD AND PROMOTING THE ARREST OF CARIES IN CHILDREN
This 1928 study found that vitamin D-rich diets helped prevent tooth decay in children and could even stop existing cavities from getting worse.
- Gut Health
The Adaptation Of Digestive Enzymes To The Diet Its Physiological Significance
Your digestive system intelligently adjusts the production of enzymes that break down food based on what you regularly eat.
- Skin and Hair Health
The Adaptor Protein Melanophilin Regulates Dynamic Myosin Va Cargo Interaction And Dendrite Development In Melanocytes
Scientists discovered how proteins work together to transport pigment-containing structures in skin cells, which is essential for proper hair and skin color development.
- Gut Health
The Adult Intestinal Core Microbiota Is Determined
Researchers studied which gut bacteria are commonly shared among healthy adults and found that the "core" gut microbiome varies significantly based on health status and how deeply scientists analyze the samples.
- Heart Health
THE ANDROGEN RECEPTOR PLAYS DIFFERENT ROLES IN MACROPHAGE INDUCED PROLIFERATION IN PROSTATE STROMAL CELLS BETWEEN TRANSITIONAL AND PERIPHERAL ZONES OF BENIGN PROSTATIC HYPERTROPHY
Researchers discovered that immune cells called macrophages promote prostate enlargement differently in various parts of the prostate, which could lead to better targeted treatments.
- Hormone Health
The Association Between Sugar Sweetened Beverages And Male Pattern Hair Loss In Young Men
A study of over 1,000 young Chinese men found that drinking more sugar-sweetened beverages was linked to a higher risk of male pattern baldness.
- Liver and Kidney Health
The Association Between TMAO, CMPF, And Clinical Outcomes In Advanced Chronic Kidney Disease Results From The European QUALity (EQUAL) Study
Researchers found that TMAO, a compound from red meat and fish, may affect heart and kidney health differently depending on its dietary source in older adults with kidney disease.
- Liver and Kidney Health
The Biochemistry And Physiology Of Mitochondrial Fatty Acid β Oxidation And Its Genetic Disorders
This research review explains how our cells break down fats for energy and what happens when genetic disorders disrupt this crucial process.
- Heart Health
THE BLOOD CHOLESTEROL FOLLOWING REPEATED ADMINISTR
A 1930 study found that repeated exposure to certain anesthetic chemicals caused blood cholesterol levels to rise significantly above normal in laboratory rabbits.
- Heart Health
The Cardiometabolic Consequences Of Replacing Saturated Fats With Carbohydrates Or Ω 6 Polyunsaturated Fats Do The Dietary Guidelines Have It Wrong
This research challenges decades of dietary advice by showing that replacing saturated fats with refined carbohydrates may have worsened America's diabetes and obesity epidemics.
- Nutrition and Health
The Carnivorous Diet
This 1886 medical journal article discusses the traditional medicinal uses of different parts of the mango tree, particularly for digestive issues and bleeding disorders.
- Nutrition and Health
The Chemistry Of The Ketogenic Diet Updates And Opportunities In Organic Synthesis
Scientists are exploring new chemical compounds that could provide ketogenic diet benefits without requiring strict adherence to the high-fat, low-carb eating plan.
- Heart Health
The Cholesterol Paradox In Long Livers From A Sardinia Longevity Hot Spot (Blue Zone)
A study of people in their 90s from Sardinia's "Blue Zone" found that those with higher LDL ("bad") cholesterol levels actually lived longer than those with lower levels.
- Heart Health
The Cholesterol Paradox In Long Livers From Sardinia
Researchers found that people in their 90s from Sardinia's "Blue Zone" lived longer when they had higher cholesterol levels, challenging conventional wisdom about cholesterol and heart health.
- Nutrition and Health
The Cognitive Contexts Of Beliefs About The Healthiness Of Meat
This study found that people's beliefs about whether meat is healthy or unhealthy are influenced by their moral, environmental, and social values—not just nutrition knowledge.
- Mental Health
The Current Status Of The Ketogenic Diet In Psychiatry
Researchers reviewed 15 studies examining whether ketogenic diets might help treat mental health conditions like anxiety, depression, and ADHD, finding mixed but promising early results.
- Liver and Kidney Health
The Dark Side Of The Spoon Glucose, Ketones And COVID 19 A Possible Role For Ketogenic Diet
This research explores how ketogenic diets might help reduce COVID-19 risk by lowering inflammation and improving metabolic conditions like obesity and diabetes.
- Nutrition and Health
The Development Of Essential Fatty Acid Deficiency In Healthy Men Fed Fat Free Diets Intravenously And Orally
This study showed that healthy men developed essential fatty acid deficiency within just two weeks when fed diets containing no fat, even when receiving adequate calories.
- Evolutionary Health and Aging
The Diet Of Canadian Indians And Eskimos
This 1953 research examined the traditional diets of Canadian Inuit and Indigenous peoples, who thrived on high-fat, animal-based foods with minimal plant foods.
- Nutrition and Health
The Discovery Of The Vitamins
This article traces the century-long scientific journey of discovering vitamins, from early experiments in the 1800s to identifying these essential nutrients that prevent diseases like scurvy and rickets.
- Nutrition and Health
The Double Burden Of Malnutrition Among Adolescents Analys 2018 The America
A large study of teenagers in developing countries found that malnutrition now includes both being underweight and overweight, affecting over 1 in 5 adolescents.
- Environment and Health
The Dublin Declaration Of Scientists On The Societal Role Of Livestock
Scientists declare that livestock-derived foods like meat, dairy, and eggs provide essential nutrients that are difficult to obtain elsewhere, especially for vulnerable populations.
- Evolutionary Health and Aging
The Ecology, Subsistence And Diet Of ~45,000 Year Old Homo Sapiens At Ilsenhöhle In Ranis, Germany
Scientists analyzed 45,000-year-old human remains in Germany to understand what early humans ate and how they survived in harsh ice-age conditions.
- Nutrition and Health
The Effect Of A 2 Week Ketogenic Diet, Versus A Carbohydrate Based Diet, On Cognitive Performance, Mood And Subjective Sleepiness During 36 Hours Of Extended Wakefulness In Military Personnel
A ketogenic diet helped military personnel maintain better mental performance, mood, and alertness during 36 hours without sleep compared to a high-carbohydrate diet.
- Environment and Health
The Effect Of Farmed Trout On Cardiovascular Risk Markers In Healthy Men
Eating farmed trout daily for 8 weeks didn't significantly improve heart health markers in healthy men, regardless of what the fish were fed.
- Liver and Kidney Health
The Effect Of Insulin On Renal Sodium Metabolism
Insulin helps the kidneys retain sodium (salt), which may explain why diabetes, obesity, and starvation affect blood pressure and fluid balance.
- Heart Health
The Effect Of Oral Glucose Tolerance Testing On Changes In Arterial Stiffness And Blood Pressure In Elderly Women With Hypertension And Relationships Between The Stage Of Diabetes And Physical Fitness Levels
This study found that elderly women with both high blood pressure and diabetes showed impaired blood vessel responses after consuming a glucose drink, suggesting compromised vascular health.
- Mental Health
The Effect Of Polyphenolic Extract From Pine Bark, Pycnogenol® On The Level Of Glutathione In Children Suffering From Attention Deficit Hyperactivity Disorder (ADHD)
Researchers studied whether Pycnogenol (pine bark extract) could improve antioxidant levels in children with ADHD by measuring glutathione, a key protective compound in the body.
- Environment and Health
The Effect Of Sauna Bathing On Lipid Profile In Young, Physically Active, Male Subjects
Regular sauna bathing for three weeks significantly lowered total cholesterol and "bad" LDL cholesterol in healthy young men, with effects similar to moderate exercise.
- Brain and Nerve Health
The Effect Of The Ketogenic Diet On Adiponectin, Omentin And Vaspin In Children With Drug Resistant Epilepsy
A ketogenic diet increased beneficial fat hormones and improved metabolic markers in children with hard-to-treat epilepsy compared to standard epilepsy medication.
- Heart Health
The Effect Of α Tocopherol Supplementation On LDL Oxidation A Dose Response Study
Researchers tested different doses of vitamin E supplements to find the minimum amount needed to protect LDL cholesterol from becoming oxidized and potentially harmful to arteries.
- Liver and Kidney Health
The Effects Of A High Protein Diet On Indices Of Health And Body Composition – A Crossover Trial In Resistance Trained Men
A study of resistance-trained men found that eating very high amounts of protein (over 3 grams per kilogram of body weight daily) for 8 weeks did not harm liver or kidney function.
- Joint, Muscle Health and Exercise
The Effects Of A Ketogenic Diet On Exercise Metabolism And Physical Performance In Off Road Cyclists
Researchers found that off-road cyclists following a ketogenic (very low-carb, high-fat) diet for several weeks showed improved oxygen efficiency and body composition, though their maximum power output decreased.
- Joint, Muscle Health and Exercise
The Effects Of A Ketogenic Diet On Exercise Metabolism And Physical Performance In Off Road Cyclists(1)
A study of off-road cyclists found that following a ketogenic diet for several weeks improved certain measures of fitness while changing how the body burns fuel during exercise.
- Liver and Kidney Health
The Effects Of A Low Carbohydrate Ketogenic Diet And A Low Fat Diet On Mood, Hunger, And Other Self Reported Symptoms
A study comparing low-carb ketogenic and low-fat diets found that both improved mood and symptoms, but the ketogenic diet was better for reducing negative feelings and hunger.
- Liver and Kidney Health
The Effects Of A Low Carbohydrate, Ketogenic Diet On The Polycystic Ovary Syndrome A Pilot Study
A very low-carb ketogenic diet significantly improved weight, hormone levels, and insulin function in women with PCOS over six months.
- Evolutionary Health and Aging
The Effects Of A Protein Enriched Diet With Lean Red Meat Combined With A Multi Modal Exercise Program On Muscle And Cognitive Health And Function In Older Adults Study Protocol For A Randomised Controlled Trial
This study protocol examines whether older adults who eat lean red meat three times weekly plus resistance training can better maintain muscle mass and brain function compared to those doing exercise alone.
- Joint, Muscle Health and Exercise
The Effects Of Carbohydrate Versus Fat Restriction On Lipid Profiles In Highly Trained, Recreational Distance Runners A Randomized, Cross Over Trial
This study compared how low-carb, high-fat versus high-carb, low-fat diets affected cholesterol and other blood fats in trained distance runners.
- Joint, Muscle Health and Exercise
The Effects Of Carbohydrate Versus Fat Restriction On Lipid Profiles In Highly Trained, Recreational Distance Runners A Randomized, Cross Over Trial (1)
This study compared how low-carb versus high-carb diets affected cholesterol and other blood fats in highly trained distance runners over six weeks.
- Nutrition and Health
The Effects Of Diet On Inflammation Emphas 2006 Journal Of The American Col
This research shows that certain foods can either increase or decrease harmful inflammation in your body, which directly affects your risk of heart disease and metabolic problems.
- Nutrition and Health
The Effects Of Dietary Fibre Type On Satiety Related Hormones And Voluntary Food Intake In Dogs
This study found that dogs fed high-fiber diets with fermentable fiber (like beet pulp) ate less food voluntarily, suggesting fiber helps control appetite and could prevent obesity.
Disclaimer: this library, including every summary, is for general informational and educational purposes only. It does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before changing your diet, exercise, or health regimen, or if you have questions about a medical condition.