Metabolic
Library
1,810 peer-reviewed papers, each with a plain-language summary and the source document. The evidence behind the VALIA method, kept where you can read it.
Educational information only. Not medical advice, diagnosis or treatment. For anything about your own health, speak with a clinician. To become a patient, start at our contact page.
1,810 papers
· 13 topics
Heart Health results
360 results in Heart Health · page 5 of 8
- Heart Health
JACC Focus Seminar Framingham Heart Study
The Framingham Heart Study, launched in 1948, became the longest-running research project tracking heart disease causes and risk factors across multiple generations of families.
- Heart Health
Ketogenic Diet And Cardiac Substrate Metabolism
Researchers reviewed how ketogenic diets affect heart metabolism, finding potential cardiovascular benefits through improved heart energy use, but also noting concerns about elevated cholesterol levels.
- Heart Health
Ketogenic Diet And Cardiac Substrate Metabolism
This research review examines how ketogenic diets affect heart metabolism and whether they may help prevent heart disease, despite some potential cardiovascular risks.
- Heart Health
Ketogenic Diet Suppressed T Regulatory Cells And Promoted Cardiac Fibrosis Via Reducing Mitochondria Associated Membranes And Inhibiting Mitochondrial Function
This study found that ketogenic diets may harm heart function in diabetic mice by reducing protective immune cells and increasing heart scarring, despite improving blood sugar control.
- Heart Health
Ketone Body 3 Hydroxybutyrate Ameliorates Atherosclerosis Via Receptor Gpr109a Mediated Calcium Influx
Researchers found that 3-hydroxybutyrate, a ketone body produced during fasting or ketogenic diets, significantly reduced artery-clogging plaque in mice by reducing harmful inflammation.
- Heart Health
Ketone Body Improves Neurological Outcomes After Cardiac Arrest By Inhibiting Mitochondrial Fission In Rats
Researchers found that ketones (β-hydroxybutyrate) protected brain function and improved survival in rats after cardiac arrest by preserving the health of cellular powerhouses called mitochondria.
- Heart Health
Ketone Body β Hydroxybutyrate Prevents Myocardial Oxidative Stress In Septic Cardiomyopathy
Researchers found that beta-hydroxybutyrate, a ketone body produced during fasting or ketogenic diets, may protect the heart from damage during severe infections called sepsis.
- Heart Health
Ketones Flux Through BDH1 Supports Metaboic Remodeling Of Skeletal And Cardiac Muscles
Researchers found that a specific enzyme helps heart and skeletal muscles use ketones more efficiently during intermittent time-restricted eating, improving fat burning and exercise performance.
- Heart Health
Ketones Step To The Plate A Game Changer For Metabolic Remodeling In Heart Failure
New research shows that failing hearts switch from using fats and sugars to using ketones (molecules made during fasting) as their primary fuel source.
- Heart Health
Ketosis Prevents Abdominal Aortic Aneurysm Progression And Rupture In Male Rats
Researchers identified seven blood markers that may actually cause peripheral artery disease (blocked leg arteries), which could help doctors better predict and prevent this serious condition.
- Heart Health
Large Scale Metabolomic Profiling Identifies Novel Biomarkers For Incident Coronary Heart Disease
Researchers identified four blood molecules that can help predict heart disease risk, potentially improving early detection beyond traditional risk factors.
- Heart Health
LDL And CV Dz
Researchers found that having "normal" LDL cholesterol levels doesn't always protect against heart attacks, challenging the common belief that lower cholesterol is always better.
- Heart Health
Lean Mean And Ox Stress
A study found that eating lean red meat instead of some carbs for 8 weeks didn't increase harmful inflammation or oxidative stress in the body.
- Heart Health
Length Of Residence In The United States Is Associated With A Higher Prevalence Of Cardiometabolic Risk Factors In Immigrants A Contemporary Analysis Of The National Health Interview Survey
Immigrants who live in the US for 10 or more years have higher rates of obesity, diabetes, and high blood pressure than newer immigrants.
- Heart Health
Lifestyle Intervention Reduces Body Weight And Improves Cardiometabolic Risk Factors In Worksites
A workplace wellness program that combined healthy eating guidance with behavior change support helped employees lose an average of 8 pounds and improve their heart health markers.
- Heart Health
Lifetime Cardiovascular Risk Of Childhoo 2010 The American Journal Of Clinic
Childhood obesity significantly increases the risk of developing heart disease later in life due to multiple health complications that damage blood vessels over time.
- Heart Health
Lipid Energy Model
Researchers propose a new model explaining why some lean people on low-carb diets develop very high cholesterol levels that may not indicate heart disease risk.
- Heart Health
Lipid Keratopathy And Atheroma
Researchers found that fatty deposits in the eye's cornea are similar to fatty plaques in arteries, suggesting both conditions may develop through comparable processes.
- Heart Health
Lipid Lowering Therapy And Hemorrhagic Stroke Risk Comparative Meta Analysis Of Statins And PCSK9 Inhibitors
This large study found that statin medications slightly increase bleeding stroke risk, while newer PCSK9 inhibitor drugs do not carry this same risk.
- Heart Health
Lipid Profiles And All Cause Mortality
A study of Chinese centenarians found that higher total cholesterol levels were associated with lower risk of death, challenging conventional wisdom about cholesterol.
- Heart Health
Lipoic Acid And Cardiovascular Disease 2003 The Journal Of Nutrition
Alpha-lipoic acid (ALA) is a powerful antioxidant that may protect against heart disease by reducing harmful oxidation, improving cholesterol levels, and supporting blood pressure.
- Heart Health
Lipoprotein Lipase Enhances The Binding Of Native And Oxidized Low Density Lipoproteins To Versican And Biglycan Synthesized By Cultured Arterial Smooth Muscle Cells
Researchers found that an enzyme called lipoprotein lipase helps bad cholesterol stick to artery wall proteins, which may worsen plaque buildup and heart disease.
- Heart Health
Long Term Calorie Restriction Is Highly Effective In Reducing The Risk For Atherosclerosis In Humans
Long-term calorie restriction significantly reduces heart disease risk by improving cholesterol, blood pressure, and artery health compared to typical American diets.
- Heart Health
Long Term Low Calorie Low Protein Vegan Diet And Endurance Exercise Are Associated With Low Cardiometabolic Risk
A long-term low-calorie vegan diet and regular endurance exercise both significantly reduce heart disease risk factors compared to a typical Western diet.
- Heart Health
Loss Of Metabolic Flexibility In The Failing Heart
When the heart fails, it loses its ability to efficiently switch between different fuel sources like fats and sugars, which worsens heart function.
- Heart Health
Lovastatin Decreases Coenzyme Q Levels In Humans
Researchers found that lovastatin, a cholesterol-lowering medication, also reduces levels of coenzyme Q10, a nutrient essential for heart function.
- Heart Health
Low Carbohydrate High Protein Diet And Incidence Of Cardiovascular Diseases In Swedish Women Prospective Cohort Study
A large Swedish study found that women following low-carb, high-protein diets for many years had a slightly higher risk of developing heart disease and stroke.
- Heart Health
Low Carbohydrate–high Protein Diets Is There A Place For Them In Clinical Cardiology
This research examines whether low-carb, high-protein diets like Atkins are safe and effective alternatives to traditional low-fat diets for heart health.
- Heart Health
Low Cholesterol Is Associated With Mortality From Cardiovascular Diseases A Dynamic Cohort Study In Korean Adults
A Korean study found that both very low cholesterol (under 160 mg/dL) and very high cholesterol (240+ mg/dL) were linked to higher heart disease death rates.
- Heart Health
Low Dose 1,3 Butanediol Reverses Age Associated Vascular Dysfunction Independent Of Ketone Body β Hydroxybutyrate
Researchers found that low doses of a compound called 1,3-butanediol can restore healthy blood vessel function in aging rats without producing ketones.
- Heart Health
Low Lipoprotein(a) Concentration Is Associated With Cancer And All Cause Deaths A Population Based Cohort Study
A large Japanese study found that people with very low levels of lipoprotein(a), a type of cholesterol particle, had higher rates of cancer and death from all causes.
- Heart Health
Lower Lifetime Dietary Fiber Intake Is Associated With 2012 The American Jou
People who ate less fiber throughout their teens and twenties had stiffer, less healthy arteries by age 36, suggesting fiber protects heart health from a young age.
- Heart Health
LowFat Ideology
This historical analysis reveals how low-fat diet recommendations became widespread in America despite lacking strong evidence for preventing heart disease or promoting weight loss.
- Heart Health
LpA II B C D E A New Immunochemically Defined Acute Phase Lipoprotein In Humans
Researchers discovered a new type of cholesterol particle that increases during inflammation and may help the body fight infections and heal damaged tissues.
- Heart Health
Lysosomal Acid Lipase As A Molecular Target Of The Very Low Carbohydrate Ketogenic Diet In Morbidly Obese Patients The Potential Effects On Liver Steatosis And Cardiovascular Risk Factors
A very low-carb ketogenic diet for 25 days helped severely obese patients lose weight, improve liver health, and boost activity of an important fat-processing enzyme.
- Heart Health
Macrophages In Cardiovascular Disease
This research review explains how immune cells called macrophages both cause heart damage through inflammation and help hearts heal after injury.
- Heart Health
Markedly Increased Intake Of Refined Carbohydrates And Sugar Is Associated With The Rise Of Coronary Heart Disease And Diabetes Among The Alaskan Inuit
A study of Alaskan Inuit people found that switching from their traditional low-sugar diet to a Western diet high in refined carbohydrates increased their rates of heart disease and diabetes.
- Heart Health
Meat Intake And Cause Specific Mortality
A large Asian study found that meat consumption was not linked to higher death rates, unlike studies in Western populations.
- Heart Health
Mechanism Of Calcification In Cardiovascular Diseases
Researchers studied how calcium deposits form in heart arteries and tissues, which can make blood vessels stiff and increase heart disease risk.
- Heart Health
Mechanisms And Clinical Consequences Of Vascular Calcification
Calcium buildup in blood vessels is not just passive aging but an active, bone-like process that significantly increases heart attack and stroke risk.
- Heart Health
Mechanisms Of Oxidized LDL Mediated Endothelial Dysfunction And Its Consequences For The Development Of Atherosclerosis
This research explains how damaged "bad" cholesterol (oxidized LDL) harms blood vessel walls and drives the development of atherosclerosis, the underlying cause of heart attacks and strokes.
- Heart Health
Medial Injury Dysfunction Induced Granulation Tissue Repair Is The Pathogenesis Of Atherosclerosis
Researchers propose that atherosclerosis (artery hardening) begins when the middle layer of artery walls gets damaged, triggering a repair process that actually creates the dangerous plaques.
- Heart Health
Medical Reversal Why We Must Raise The Bar Before Adopting New Technologies
Medical "reversal" happens when better studies prove that widely-used treatments don't actually work, highlighting why new medical technologies need stronger evidence before adoption.
- Heart Health
Mediterranean Versus Vegetarian Diet For Cardiovascular Disease Prevention (the CARDIVEG Study) Study Protocol For A Randomized Controlled Trial
Researchers are comparing Mediterranean and vegetarian diets head-to-head to determine which is better for preventing heart disease in overweight adults.
- Heart Health
Meta Analysis Of Prospective Cohort Studies Evaluating The Association Of Saturated Fat With Cardiovascular Disease
This large analysis of 21 studies found no evidence that eating saturated fat increases the risk of heart disease or stroke.
- Heart Health
Meta Analysis Of Randomized Controlled Trials Of Red Meat Consumption In Comparison With Various Comparison Diets On Cardiovascular Risk Factors
This study found that replacing red meat with high-quality plant proteins like beans and nuts improves cholesterol levels, but the comparison food matters more than eliminating red meat alone.
- Heart Health
Metabolism Of Exogenous [2,4 13C]β Hydroxybutyrate Following Traumatic Brain Injury In 21 22 Day Old Rats An Ex Vivo NMR Study
Researchers found that young rats with brain injuries used more ketones (alternative brain fuel) for energy, suggesting ketones may help support brain healing after trauma.
- Heart Health
Mevinolin, An Inhibitor Of Cholesterol Synthesis, Induces MRNA For Low Density Lipoprotein Receptor In Livers Of Hamsters And Rabbits
Researchers found that mevinolin (a cholesterol-lowering drug) works by increasing the liver's production of receptors that remove harmful cholesterol from the blood.
Disclaimer: this library, including every summary, is for general informational and educational purposes only. It does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before changing your diet, exercise, or health regimen, or if you have questions about a medical condition.