Metabolic
Library
1,810 peer-reviewed papers, each with a plain-language summary and the source document. The evidence behind the VALIA method, kept where you can read it.
Educational information only. Not medical advice, diagnosis or treatment. For anything about your own health, speak with a clinician. To become a patient, start at our contact page.
1,810 papers
· 13 topics
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1,810 results · page 11 of 38
- Heart Health
Dl 3 Hydroxybutyrate Administration Prevents Myocardial Damage After Coronary Occlusion In Rat Hearts
Researchers found that giving ketones (specifically 3-hydroxybutyrate) to fasted rats before blocking their heart arteries significantly reduced heart damage and cell death.
- Nutrition and Health
Do Children Eat Less At Meals When Allowed T 2012 The American Journal Of Cl
A study of young children found that letting them serve themselves food doesn't reduce how much they eat, and some children may need guidance with portion sizes.
- Liver and Kidney Health
Do Ketone Bodies Mediate The Anti Seizure Effects Of The Ketogenic Diet
Researchers are investigating whether ketone bodies (molecules produced during ketosis) are responsible for the ketogenic diet's ability to reduce seizures in epilepsy patients.
- Heart Health
Does A Ketogenic Diet Lower A Very High Lp(a) A Striking Experiment In A Male Physician
A physician discovered that switching from a ketogenic diet to a high-carb diet caused his Lp(a) levels—a heart disease risk marker—to increase significantly within just two weeks.
- Joint, Muscle Health and Exercise
Does Exercise During A Ketogenic Diet Effectively Alter Appetite Sensation, Appetite Regulating Hormones, And Body Composition
This study found that combining either aerobic or resistance exercise with a ketogenic diet improved appetite control hormones and body composition better than diet alone.
- Joint, Muscle Health and Exercise
Does Exercise During A Ketogenic Diet Effectively Alter Appetite Sensation, Appetite Regulating Hormones, And Body Composition
This study found that combining either aerobic or resistance exercise with a ketogenic diet improved appetite control hormones and body composition better than following a ketogenic diet alone.
- Joint, Muscle Health and Exercise
Does Exercise During A Ketogenic Diet Effectively Alter Appetite Sensation, Appetite Regulating Hormones, And Body Composition(1)
This study found that adding either aerobic or resistance exercise to a ketogenic diet improved appetite control and body composition more than following a ketogenic diet alone.
- Heart Health
Does Fish Oil Lower Blood Pressure A Meta Analysis Of Controlled Trials
This study found that fish oil supplements can modestly lower blood pressure, with stronger effects at higher doses and in people who already have high blood pressure.
- Gut Health
Does Poultry Consumption Increase The Risk Of Mortality For Gastrointestinal Cancers A Preliminary Competing Risk Analysis
A study of nearly 5,000 people in Italy found that eating more than 300 grams of poultry per week may increase the risk of death from gastrointestinal cancers.
- Hormone Health
Dopamine And Glucose, Obesity, And Reward Deficiency Syndrome
This research explores how dopamine brain chemistry dysfunction may drive both food addiction and overeating, similar to how it works in drug addiction.
- Heart Health
Doxorubicin Induced P53 Interferes With Mitophagy In Cardiac Fibroblasts
Researchers discovered how the cancer drug doxorubicin damages heart cells over time by interfering with the cell's ability to clean out damaged parts.
- Environment and Health
Drinking Water Constituents And Disease1 2 3 2008 The Journal Of Nutrition
Research suggests that drinking water with adequate minerals (magnesium, calcium) and proper pH levels may help protect against heart disease and bone loss.
- Brain and Nerve Health
Du Et Al 2025 High And Low Fat Dairy Consumption And Long Term Risk Of Dementia
A 25-year study of nearly 28,000 people found that eating high-fat dairy products like cheese and cream was linked to lower dementia risk.
- Heart Health
Dynamic Regulation Of Lipid Protein 2015 Biochimica Et Biophysica Acta BBA
This research reviews how proteins in cell membranes move and change shape to control important heart and metabolic functions like ion channels and cellular signaling.
- Gut Health
Dynamics Of The Human Gut Microbiome In Inflammatory Bowel Disease
This study tracked changes in gut bacteria over time in people with inflammatory bowel disease, revealing how the microbiome becomes unstable during disease flares.
- Evolutionary Health and Aging
Earliest Archaeological Evidence Of Persistent Hominin Carnivory
Archaeological evidence from Kenya shows our ancestors were regularly eating meat 2 million years ago, making carnivory a key part of human evolution.
- Dental Health
Earliest Evidence For Caries And Exploitation Of Starchy Plant Foods In Pleistocene Hunter Gatherers From Morocco
Ancient hunter-gatherers from Morocco 15,000 years ago had tooth decay rates as high as modern people, caused by eating starchy wild plants like acorns and pine nuts.
- Evolutionary Health and Aging
Earliest Fire In Africa Towards The Convergence Of Archaeological Evidence And The Cooking Hypothesis
This study examines archaeological evidence for when early humans first began using fire for cooking, which may have been crucial for human brain development and metabolism.
- Heart Health
Early Human Atherosclerosis Accumulation Of Lipid And Proteoglycans In Intimal Thickenings Followed By Macrophage Infiltration
Researchers studied how heart disease begins, finding that fat and certain proteins accumulate in artery walls before immune cells arrive to clean up the damage.
- Nutrition and Health
Early Initiation And Exclusivity Of Breastfeeding
A study in rural Zimbabwe found that village health workers can effectively help new mothers start breastfeeding earlier and breastfeed exclusively for longer periods.
- Heart Health
Early Microvascular Dysfunction Is The Vasa Vasorum A “Missing Link” In Insulin Resistance And Atherosclerosis
Researchers are investigating whether damage to tiny blood vessels that feed artery walls could be the missing link between insulin resistance and heart disease.
- Nutrition and Health
Eating Vegetables First The Use Of Portion Size T 2010 The American Journal
Serving larger portions of vegetables as a first course before meals significantly increased how many vegetables preschool children ate.
- Environment and Health
Ecosystem Impacts And Productive Capacity Of A Multi Species Pastured Livestock System
Researchers found that raising multiple types of livestock together on pastures can dramatically reduce greenhouse gas emissions while improving soil health compared to conventional farming methods.
- Liver and Kidney Health
Effect Of 2 Year Caloric Restriction On Organ And Tissue Size In Nonobese 21 To 50 Year Old Adults In A Randomized Clinical Trial The CALERIE Study
A two-year study found that moderate calorie restriction in healthy adults led to fat loss (especially dangerous belly fat) while preserving most muscle and organ tissue.
- Joint, Muscle Health and Exercise
Effect Of A Four Week Ketogenic Diet On Exercise Metabolism In CrossFit Trained Athletes
A four-week ketogenic diet helped male CrossFit athletes burn more fat during moderate-intensity exercise, but had less effect on female athletes.
- Joint, Muscle Health and Exercise
Effect Of A Four Week Ketogenic Diet On Exercise Metabolism In CrossFit Trained Athletes(1)
A four-week ketogenic diet helped male CrossFit athletes burn more fat during exercise, but showed less effect in female athletes.
- Nutrition and Health
Effect Of A High Protein Energy Restricted Diet On Body 2003 The American
A high-protein diet helped overweight people with insulin resistance preserve muscle mass during weight loss and showed better blood sugar control than a standard-protein diet.
- Liver and Kidney Health
Effect Of A Ketogenic Diet On Hepatic Steatosis And Hepatic Mitochondrial Metabolism In Nonalcoholic Fatty Liver Disease
A 6-day ketogenic diet reduced fatty liver by 31% in overweight people by changing how the liver processes fats, shifting from fat storage to fat burning.
- Joint, Muscle Health and Exercise
Effect Of Anti Inflammatory Diets On Pain In Rheumatoid Arthritis A Systematic Review And Meta Analysis
Researchers analyzed whether anti-inflammatory diets like Mediterranean, vegetarian, vegan, and ketogenic eating patterns can reduce joint pain in people with rheumatoid arthritis.
- Heart Health
Effect Of Cheese Intake On Cardiovascular Diseases And Cardiovascular Biomarkers
This study found that eating cheese may reduce the risk of heart disease, diabetes, and stroke while improving metabolic health markers like body weight and blood sugar.
- Nutrition and Health
Effect Of Conjugated Linoleic Acid On Body Fat A 2010 The American Journal O
A study found that conjugated linoleic acid (CLA) supplements helped reduce body fat in overweight children aged 6-10, but also lowered beneficial HDL cholesterol.
- Gut Health
Effect Of Consumption Of Animal Products On The Gut Microbiome Composition And Gut Health
Different animal products like red meat, dairy, and eggs each affect gut bacteria composition differently, with varying impacts on digestive health.
- Heart Health
Effect Of Dietary Cholesterol And Cholesterol Oxides On Blood Cholesterol, Lipids, And The Development Of Atherosclerosis In Rabbits
This rabbit study found that both dietary cholesterol and oxidized cholesterol (damaged cholesterol compounds) raised blood cholesterol levels and caused artery damage that leads to heart disease.
- Nutrition and Health
Effect Of Dietary Fatty Acids On MicroRNA Expression Related To Metabolic Disorders And Inflammation In Human And Animal Trials
This research review examines how different types of dietary fats affect tiny molecules called microRNAs that help regulate metabolism and inflammation in the body.
- Heart Health
Effect Of Dietary Fatty Acids On Serum Lipids And Lipoproteins. A Meta Analysis Of 27 Trials
This study found that replacing saturated fats with unsaturated fats (rather than carbohydrates) provides the best cholesterol profile for heart health.
- Heart Health
Effect Of Dietary Fatty Acids On Serum Lipids And Lipoproteins. A Meta Analysis Of 27 Trials.
This study found that replacing saturated fats with unsaturated fats (rather than carbohydrates) creates the best cholesterol profile for heart health.
- Nutrition and Health
Effect Of Dietary Macronutrient Composition Under Moderate Hypocaloric Intake On Maternal Adaptation During Lactation
Breastfeeding mothers on a high-fat, low-carb diet burned more energy and had better weight loss while maintaining milk quality compared to a high-carb diet.
- Heart Health
Effect Of Different Forms Of Dietary Hydrogena 2003 The American Journal Of
This study found that eating trans fats (found in some margarines and processed foods) makes LDL cholesterol particles smaller and denser, which is worse for heart health.
- Nutrition and Health
Effect Of Diurnal Variations In The Carbohydrate And Fat 2018 The American
Eating a high-carbohydrate meal after a high-fat meal causes blood sugar to spike about 20% higher than eating consistent meals throughout the day.
- Hormone Health
Effect Of Extended Morning Fasting Upon Ad Libitum Lunch Intake And Associated Metabolic And Hormonal Responses In Obese Adults
Skipping breakfast doesn't cause people with obesity to overeat at lunch, and may actually reduce total daily calorie intake.
- Heart Health
Effect Of Fatty And Lean Fish Intake On Lipoprotei
Eating fatty fish at least four times per week increases the size of beneficial HDL ("good") cholesterol particles in people with heart disease.
- Heart Health
Effect Of Intensive Versus Moderate Lipid Lowering Therapy On Epicardial Adipose Tissue In Hyperlipidemic Post Menopausal Women A Substudy Of The BELLES Trial (Beyond Endorsed Lipid Lowering With EBT Scanning)
High-dose statin therapy reduced harmful fat around the heart more effectively than moderate-dose therapy in postmenopausal women with high cholesterol.
- Nutrition and Health
Effect Of Iron Intake On Iron Status A Systematic 2012 The American Journa
This study found that iron supplements improve iron levels in the blood, with higher doses and longer treatment periods leading to greater improvements.
- Heart Health
Effect Of Ketogenic Mediterranean Diet With Phytoextracts And Low Carbohydrates High Protein Meals On Weight, Cardiovascular Risk Factors, Body Composition And Diet Compliance In Italian Council Employees
A modified ketogenic Mediterranean diet with special protein-rich meal replacements helped Italian office workers lose weight and improve heart health markers over 6 weeks.
- Nutrition and Health
Effect Of Orange Juice Intake On Vitamin C Concentr 2003 The American Journa
Drinking 500ml of orange juice daily for two weeks significantly increased vitamin C levels in the blood and reduced markers of oxidative stress, especially in smokers.
- Nutrition and Health
Effect Of Short Term Carbohydrate Overfeeding And L 2012 The American Journa
This study found that eating excess simple sugars for just three weeks increased liver fat much more dramatically than body weight in overweight people.
- Nutrition and Health
Effect Of Short Term Ketogenic Diet On Redox Status Of Human Blood
A 14-day ketogenic diet increased antioxidant levels in healthy women's blood without causing harmful oxidative stress.
- Heart Health
Effect Of Soy Protein Varying In Isoflavone Cont 2006 The American Journal O
Soy protein improved heart-healthy cholesterol ratios in young men, regardless of whether it contained high or low levels of plant compounds called isoflavones.
Disclaimer: this library, including every summary, is for general informational and educational purposes only. It does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before changing your diet, exercise, or health regimen, or if you have questions about a medical condition.