Metabolic
Library
1,810 peer-reviewed papers, each with a plain-language summary and the source document. The evidence behind the VALIA method, kept where you can read it.
Educational information only. Not medical advice, diagnosis or treatment. For anything about your own health, speak with a clinician. To become a patient, start at our contact page.
1,810 papers
· 13 topics
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1,810 results · page 12 of 38
- Joint, Muscle Health and Exercise
Effect Of The Ketogenic Diet In Excitable Tissues
This review explains how the ketogenic diet affects the body's electrical systems - the brain, heart, and muscles - through ketones that act as both fuel and signaling molecules.
- Hormone Health
Effect Of Time Restricted Eating On Body Weight And Fasting Glucose In Participants With Obesity Results Of A Randomized, Controlled, Virtual Clinical Trial
This study found that eating within a 10-hour window (fasting for 14 hours daily) led to greater weight loss and better blood sugar control than a 12-hour eating window in people with obesity.
- Nutrition and Health
Effect Of Two Different Sublingual Dosages Of Vitamin B12 On Cobalamin Nutritional Status In Vegans And Vegetarians With A Marginal Deficiency A Randomized Controlled Trial
A study found that taking a lower dose of vitamin B12 under the tongue (350 mcg weekly) works just as well as a higher dose (2000 mcg weekly) for correcting B12 deficiency in vegans and vegetarians.
- Gut Health
Effect Of Vegan Fecal Microbiota Transplantation On Carnitine‐ And Choline‐Derived Trimethylamine‐N‐Oxide Production And Vascular Inflammation In Patients With Metabolic Syndrome
Researchers tested whether transplanting gut bacteria from vegans into metabolic syndrome patients could reduce heart disease risk, but the treatment didn't work as expected.
- Skin and Hair Health
Effect Of Very Low Calorie Ketogenic Diet On Psoriasis Patients A Nuclear Magnetic Resonance Based Metabolomic Study
A very low-calorie ketogenic diet improved both skin symptoms and inflammation markers in psoriasis patients over four weeks.
- Heart Health
Effectiveness Of Altering Serum Cholesterol Levels Without Drugs
This research review found that dietary approaches can lower cholesterol by 0-37% without medications, though the heart health benefits may be greater than these numbers suggest.
- Mental Health
Effectiveness Of Pharmaceutical Therapy Of ADHD (Attention Deficit Hyperactivity Disorder) In Adults – Health Technology Assessment
This study found that ADHD medications like methylphenidate and amphetamines effectively reduce symptoms in adults compared to placebo treatments.
- Hormone Health
Effects Of 8 Hour Time Restricted Feeding On Body Weight And Metabolic Disease Risk Factors In Obese Adults A Pilot Study
Eating only during an 8-hour window (10am-6pm) helped obese adults lose weight and lower blood pressure without counting calories.
- Heart Health
Effects Of A Carbohydrate Restricted Diet On Emerging Plasma Markers For Cardiovascular Disease
A low-carb diet helped overweight men lose weight and improve several blood markers linked to heart disease risk, including reducing inflammation.
- Nutrition and Health
Effects Of A Combination Of Beta Carotene And Vitamin A On Lung Cancer And Cardiovascular Disease
A large study found that beta-carotene and vitamin A supplements actually increased lung cancer risk and death rates in smokers and asbestos workers, contrary to expectations.
- Heart Health
Effects Of A DASH Like Diet Containing Lean Beef On Vascular Health
A heart-healthy DASH diet that includes lean beef can lower blood pressure and improve blood vessel function in people with normal blood pressure.
- Hormone Health
Effects Of A High Protein Ketogenic Diet On Hunger, Appetite, And Weight Loss In Obese Men Feeding Ad Libitum1
A ketogenic high-protein diet (very low carb) reduced hunger and led to greater weight loss than a moderate-carb high-protein diet in obese men over four weeks.
- Liver and Kidney Health
Effects Of A Ketogenic Diet In Overweight Women With Polycystic Ovary Syndrome
A 12-week ketogenic Mediterranean diet helped overweight women with PCOS lose weight, improve insulin sensitivity, and balance hormones that affect fertility and metabolism.
- Nutrition and Health
Effects Of A Low Carbohydrate Ketogenic Diet On Reported Pain, Blood Biomarkers And Quality Of Life In Patients With Chronic Pain A Pilot Randomized Clinical Trial
A 12-week study found that both ketogenic and whole-food diets reduced chronic pain, but the ketogenic diet provided greater improvements in pain, weight loss, and inflammation.
- Hormone Health
Effects Of A Low Carbohydrate Weight Loss Diet On Exercise Capacity And Tolerance In Obese Subjects
Researchers studied whether very low-carb "ketogenic" diets affect people's ability to exercise while trying to lose weight.
- Hormone Health
Effects Of A Popular Exercise And Weight Loss Program On Weight Loss, Body Composition, Energy Expenditure And Health In Obese Women
Researchers studied how different combinations of diet and exercise programs affect weight loss and body composition in obese women over several months.
- Brain and Nerve Health
Effects Of Acetyl L Carnitine On Oxidative Stress In Amyotrophic Lateral Sclerosis Patients Evaluation On Plasma Markers And Members Of The Neurovascular Unit
Researchers found that acetyl-L-carnitine supplements helped reduce harmful oxidative stress in ALS patients over six months of treatment.
- Joint, Muscle Health and Exercise
Effects Of Ad Libitum Low Carbohydrate High Fat Dieting In Middle Age Male Runners
A 3-week low-carb, high-fat diet helped middle-aged recreational runners lose weight and burn more fat during exercise without hurting their 5K race times.
- Nutrition and Health
Effects Of Breastfeeding And Low Sugar Sweetened Be 2012 The American Journa
Breastfeeding for at least one year and avoiding sugary drinks significantly reduced obesity risk in Hispanic toddlers aged 2-4.
- Liver and Kidney Health
Effects Of Calorie Restriction On Health Span And Insulin Resistance Classic Calorie Restriction Diet Vs. Ketosis Inducing Diet
This review compared different calorie restriction approaches and found that reducing calories can improve insulin sensitivity and metabolic health, with ketogenic Mediterranean diets showing particularly strong benefits.
- Brain and Nerve Health
Effects Of Classic Ketogenic Diet In Children With Refractory Epilepsy A Retrospective Cohort Study In Kingdom Of Bahrain
A ketogenic diet helped reduce seizures by more than 50% in most children with hard-to-treat epilepsy, with one-third becoming completely seizure-free.
- Dental Health
Effects Of Developmental Failure Of Swallowing Threshold On Obesity And Eating Behaviors In Children Aged 5–15 Years
Children who don't properly sense when food is ready to swallow are more likely to be overweight and snack frequently between meals.
- Skin and Hair Health
Effects Of Diet On Acne And Its Response To Treatment
Research shows that what you eat - particularly high-sugar foods, dairy, and unhealthy fats - can significantly affect acne severity and treatment success.
- Gut Health
Effects Of Dietary Components On Intestinal Permeability In Health And Disease
This research review examines how different foods and dietary components can either strengthen or weaken the intestinal barrier that protects our body from harmful substances.
- Gut Health
Effects Of Dietary Components On Intestinal Short Chain Fatty Acids (SCFAs) Synthesis In Healthy Adult Persons Following A Ketogenic Diet
Adding more vegetables, berries, and nuts to a ketogenic diet helps produce beneficial gut bacteria byproducts called short-chain fatty acids.
- Joint, Muscle Health and Exercise
Effects Of Dietary Fat On Muscle Substrates, Metabolism, And Performance In Athletes
This study found that endurance athletes maintained their performance equally well on high-fat diets compared to high-carb diets, but their muscles adapted to burn more fat for fuel.
- Joint, Muscle Health and Exercise
Effects Of Dietary Fat On Muscle Substrates, Metabolism, And Performance In Athletes(1)
A 5-week high-fat diet doubled fat storage in athletes' muscles and shifted their bodies to burn more fat during exercise, while maintaining the same performance levels as a high-carb diet.
- Skin and Hair Health
Effects Of Fish Oil Supplementation On Inflammatory Acne
A small study found that fish oil supplements may help improve moderate to severe acne, but had mixed results and may worsen mild acne.
- Hormone Health
Effects Of Food Texture Change On Metabolic Parameters Short And Long Term Feeding Patterns And Body Weight
Food texture affects how your body processes meals - softer foods led to more weight gain and different hormone responses compared to foods requiring more chewing.
- Nutrition and Health
Effects Of Fruit And Vegetable Consumption On Inflammat 2018 The American Jo
This large research review found that eating more fruits and vegetables reduces inflammation markers in the blood, which may help protect against chronic diseases.
- Evolutionary Health and Aging
Effects Of Hyperthyroidism In The Development Of The Appendicular Skeleton And Muscles Of Zebrafish, With Notes On Evolutionary Developmental Pathology (Evo Devo Path)
Researchers studied how thyroid hormone T3 affects bone and muscle development in zebrafish, revealing insights into how thyroid function impacts growth across species including humans.
- Nutrition and Health
Effects Of Intermittent Fasting On Brain Metabolism
Intermittent fasting may protect brain health by triggering beneficial changes in brain cells, including the production of ketones that help neurons resist stress and form new connections.
- Heart Health
Effects Of Ketogenic Diets On Cardiovascular Risk Factors Evidence From Animal And Human Studies
This research review examines how ketogenic (very low-carb, high-fat) diets affect heart disease risk factors, finding mixed results with some benefits that may not last long-term.
- Brain and Nerve Health
Effects Of Ketone Bodies On Brain Metabolism And Function In Neurodegenerative Diseases
Research shows that ketone bodies (produced during fasting or ketogenic diets) can serve as alternative brain fuel and may help protect against neurodegenerative diseases like Alzheimer's and Parkinson's.
- Environment and Health
Effects Of Light On Metabolism
This research review examines how artificial light exposure - its brightness, timing, duration, and color - affects human metabolism and can increase risks of obesity and diabetes.
- Environment and Health
Effects Of Light On Sleep And Mood
This research explains how light exposure affects your body's internal clock, which controls sleep patterns and mood through a master clock in your brain.
- Liver and Kidney Health
Effects Of Low Animal Protein Or High Fiber Diets On Urine Composition In Calcium Nephrolithiasis
Researchers studied whether eating less animal protein or more fiber could help prevent kidney stone recurrence, but found no significant benefit for most patients.
- Heart Health
Effects Of Low Carbohydrate Diets V. Low Fat Diets On Body Weight And Cardiovascular Risk Factors A Meta Analysis Of Randomised Controlled Trials
Low-carb diets led to greater weight loss than low-fat diets but also raised "bad" LDL cholesterol levels, creating mixed effects on heart health.
- Nutrition and Health
Effects Of N 3 Polyunsaturated Fatty Acids (ω 3) Supplementation On Some Cardiovascular Risk Factors With A Ketogenic Mediterranean Diet
Adding omega-3 supplements to a Mediterranean-style ketogenic diet provided better improvements in heart health markers and inflammation compared to the diet alone.
- Heart Health
Effects Of Normal Pre Hypertensive And Hypertensi 2006 Journal Of The Amer
This study found that people with normal blood pressure had the least progression of artery-clogging plaque in their heart, while those with high blood pressure had the most plaque buildup.
- Hormone Health
Effects Of Nutrition Education On Weight Gain Prevention A Randomized Controlled Trial
A study of 81 women found that most participants maintained their weight over one year regardless of whether they received nutrition education from dietitians.
- Hormone Health
Effects Of Nutrition Education On Weight Gain Prevention A Randomized Controlled Trial(1)
A study of 87 women found that most participants maintained their weight over one year regardless of whether they received nutrition education from dietitians.
- Heart Health
Effects Of Oily Fish Intake On Cardiovascular Risk Markers, Cognitive Function, And Behavior In School Aged Children Study Protocol For A Randomized Controlled Trial
Researchers are studying whether eating oily fish like salmon twice a week can improve heart health, brain function, and behavior in children compared to eating chicken.
- Heart Health
Effects Of Statins On Mitochondrial Pathways
This research examines how statin medications, while beneficial for heart health, can sometimes cause muscle problems by affecting the energy-producing structures in cells called mitochondria.
- Heart Health
Effects Of Step Wise Increases In Dietary Carbohydrate On Circulating Saturated Fatty Acids And Palmitoleic Acid In Adults With Metabolic Syndrome
This study found that eating saturated fat doesn't increase saturated fat levels in your blood, but eating more carbohydrates does increase a harmful fatty acid marker.
- Heart Health
Effects Of The Ketogenic Diet In Mice With Hind Limb Ischemia
A study in mice found that ketogenic diets may impair blood flow recovery and muscle healing after tissue damage from blocked blood vessels.
- Nutrition and Health
Effects Of Two Different Dietary Patterns On Inflammatory Markers, Advanced Glycation End Products And Lipids In Subjects Without Type 2 Diabetes A Randomised Crossover Study
A study found that eating more red meat and refined grains increased a blood clotting factor linked to diabetes risk compared to eating dairy, whole grains, nuts and legumes.
- Joint, Muscle Health and Exercise
Effects Of Two Months Of Very Low Carbohydrate Ketogenic Diet On Body Composition, Muscle Strength, Muscle Area, And Blood Parameters In Competitive Natural Body Builders
A two-month ketogenic diet helped competitive bodybuilders lose fat while maintaining muscle mass and strength compared to a standard Western diet.
Disclaimer: this library, including every summary, is for general informational and educational purposes only. It does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before changing your diet, exercise, or health regimen, or if you have questions about a medical condition.