Metabolic
Library
1,810 peer-reviewed papers, each with a plain-language summary and the source document. The evidence behind the VALIA method, kept where you can read it.
Educational information only. Not medical advice, diagnosis or treatment. For anything about your own health, speak with a clinician. To become a patient, start at our contact page.
1,810 papers
· 13 topics
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1,810 results · page 19 of 38
- Environment and Health
Influence Of Feeding Moringa Oleifera Pods As Phytogenic Feed Additive On Performance, Blood Metabolites, Chemical Composition And Bioactive Compounds Of Breast Meat In Broiler
Research found that adding moringa pods to chicken feed improved the birds' growth efficiency and increased beneficial antioxidants in their meat while reducing cholesterol levels.
- Nutrition and Health
Influence Of Ketogenic Diet And Nutraceutical Correction In The Complex Treatment Of Lower Limbs Lipedema
Researchers found that a modified ketogenic diet combined with targeted supplements was more effective than a low-calorie diet for reducing fat deposits in women with lipedema, a condition causing abnormal fat accumulation in the legs.
- Nutrition and Health
Influence Of Thyroid Hormone Status On Mevalonate Metabolism In Rats
This study found that thyroid hormones directly control how the kidneys process mevalonate, a key building block used to make cholesterol in the body.
- Heart Health
Inhibition Of Plaque Neovascularization Reduces Macrophage Accumulation And Progression Of Advanced Atherosclerosis
Researchers found that blocking the growth of new blood vessels in artery plaques reduced inflammation and slowed the progression of atherosclerosis in mice.
- Environment and Health
Insufficient Sun Exposure Has Become A Real Public Health Problem
New research suggests that not getting enough sun exposure may be a serious public health problem, potentially contributing to hundreds of thousands of deaths annually in the US and Europe.
- Mental Health
Insulin Resistance And Depression
A large study found that children with persistently high insulin levels face increased risk of developing psychosis as young adults, while significant weight gain during puberty increases depression risk.
- Skin and Hair Health
Insulin Resistance And Skin Diseases
This review examines how insulin resistance connects to various skin conditions including acanthosis nigricans, acne, psoriasis, hair loss, and other dermatological problems.
- Environment and Health
Integrated Metabolomic And Transcriptome Analyses Reveal Finishing Forage Affects Metabolic Pathways Related To Beef Quality And Animal Welfare
This study compared grass-fed versus grain-fed cattle to understand how different diets affect meat quality and the animals' metabolic health.
- Mental Health
Integrated Neurobiology Of Bipolar Disorder
Bipolar disorder likely represents multiple similar but distinct brain conditions involving inflammation, immune system overactivity, and structural brain changes that worsen over time.
- Hormone Health
Interaction Of Bisphenol A (BPA) And Soy Phytoestrogens On Sexually Dimorphic Sociosexual Behaviors In Male And Female Rats
Researchers found that exposure to BPA (a chemical in plastics) and soy foods during development can affect social behaviors differently in male and female rats.
- Nutrition and Health
Interaction Of Polygenetic Variants Related To Inflammation With Carbohydrate And Vitamin D Intakes In Middle Aged And Older Adults In A Large Hospital Based Cohort
Certain genetic variants increase inflammation risk, but eating fewer carbohydrates, more healthy fats, and adequate vitamin D can help reduce this genetic disadvantage.
- Nutrition and Health
Interactive Effects Of Reward Sensitivity And Reside 2010 The American Journ
People who are highly sensitive to rewards are more likely to eat fast food when they live near fast-food restaurants.
- Nutrition and Health
Interferon λs Front Line Guardians Of Immunity And Homeostasis In The Respiratory Tract
Scientists discovered that interferon lambda proteins act as specialized immune guardians in the lungs, protecting against respiratory infections while helping regulate inflammation in diseases like asthma.
- Hormone Health
Intermittent Fasting Interventions For The Treatment Of Overweight And Obesity In Adults Aged 18 Years And Over A Systematic Review Protocol
Researchers are planning to systematically review whether intermittent fasting is an effective treatment for weight loss compared to traditional calorie-restricted diets or no dietary changes.
- Hormone Health
Intermittent Fasting Interventions For The Treatment Of Overweight And Obesity In Adults Aged 18 Years And Over A Systematic Review Protocol(1)
Researchers are systematically reviewing whether intermittent fasting is an effective treatment for weight loss compared to traditional calorie-restricted diets or no diet restrictions.
- Nutrition and Health
Intermittent Fasting To The Eye A New Dimension Involved In Physiological And Pathological Changes
Researchers reviewed how intermittent fasting may affect eye health, finding potential benefits for preventing and treating various eye diseases through improved metabolism.
- Hormone Health
Intermittent Fasting WONDERFUL
A study found that fasting for 24 hours once or twice per week lowered "bad" LDL cholesterol and improved insulin sensitivity in adults with metabolic health concerns.
- Hormone Health
Intermittent Moderate Energy Restriction Improves Weight Loss Efficiency In Diet Induced Obese Mice
A mouse study found that cycling between moderate calorie restriction and normal eating was more efficient for weight loss than continuous calorie restriction.
- Gut Health
Intestinal Barrier Permeability In Allergic Diseases
This research explores how a "leaky gut" - increased intestinal permeability - may contribute to food allergies and other allergic conditions in both children and adults.
- Gut Health
Intestinal In Vitro And Ex Vivo Models To Study Host Microbiome Interactions And Acute Stressors
This research review examines laboratory methods for studying how gut bacteria interact with the human body during times of stress and how these interactions affect health and performance.
- Gut Health
Intestinal Microbiota And Respiratory Viral Infections
Researchers discovered that certain beneficial gut bacteria can help protect against respiratory viral infections like flu and COVID-19 by strengthening immune cells in the lungs.
- Gut Health
Intestinal Permeability In Patients With Crohn’s Disease And Their Healthy Relatives
Researchers found that people with Crohn's disease have increased intestinal permeability (leaky gut), but their healthy family members showed normal gut barrier function when tested with certain molecules.
- Liver and Kidney Health
Intestinal Transcriptome Analysis Reveals Soy Derivative Linked Changes In Atlantic Salmon
Researchers found that soy-based feed ingredients caused intestinal inflammation and disrupted normal gut function in Atlantic salmon, potentially offering insights into how soy affects digestive health.
- Heart Health
Intraplaque Haemorrhages As The Trigger Of Plaque Vulnerability
Researchers found that bleeding inside artery plaques may be a key trigger that makes these plaques more likely to rupture and cause heart attacks or strokes.
- Joint, Muscle Health and Exercise
Investigating Effects Of Sodium Beta Hydroxybutyrate On Metabolism In Placebo Controlled, Bilaterally Infused Human Leg With Focus On Skeletal Muscle Protein Dynamics
Researchers found that beta-hydroxybutyrate (a ketone body) may help preserve muscle protein when infused directly into leg arteries of healthy men.
- Joint, Muscle Health and Exercise
Investigating Effects Of Sodium Beta Hydroxybutyrate On Metabolism In Placebo Controlled, Bilaterally Infused Human Leg With Focus On Skeletal Muscle Protein Dynamics(1)
Researchers directly infused beta-hydroxybutyrate (a ketone body) into leg muscles to study its effects on muscle protein breakdown and metabolism.
- Nutrition and Health
Investigating The Efficacy Of Combined Ketogenic Diet And Anti Inflammatory Therapy In A Mouse Model Of Early Onset Tay Sachs Disease
Researchers tested whether combining a ketogenic diet with anti-inflammatory medication could help treat brain inflammation in mice with Tay-Sachs disease, a rare genetic disorder.
- Dental Health
Iodine Status Modifies The Association Between Fluoride Exposure In Pregnancy And Preschool Boys’ Intelligence
A study found that low iodine levels during pregnancy may worsen the negative effects of fluoride exposure on young boys' brain development and intelligence.
- Liver and Kidney Health
Iron Deficiency In Patients With Nonalcoholic Fatt
This study found that one-third of people with fatty liver disease also have iron deficiency, especially women and those with obesity.
- Joint, Muscle Health and Exercise
Is A Four Week Ketogenic Diet An Effective Nutritional Strategy In CrossFit Trained Female And Male Athletes
A four-week ketogenic diet reduced aerobic fitness in female CrossFit athletes and caused concerning blood changes in both men and women, without improving exercise performance.
- Environment and Health
Is A Healthy Diet An Environmentally Sustainable Diet
Research shows that while healthy diets can have lower greenhouse gas emissions, not all nutritionally adequate diets are automatically environmentally sustainable.
- Heart Health
Is Atherosclerotic Plaque Rupture Necessarily Detrimental? Not Always
New research suggests that when atherosclerotic plaques (fatty deposits in arteries) rupture, the outcome isn't always harmful and may sometimes lead to improvement.
- Gut Health
Is Dietary Fiber Considered An Essential Nutrient
Dietary fiber from whole foods provides important health benefits and may be more effective than synthetic fiber supplements added to processed foods.
- Gut Health
Is Eating Behavior Manipulated By The Gastrointestinal Microbiota Evolutionary Pressures And Potential Mechanisms
Scientists propose that gut bacteria may manipulate our food cravings to benefit themselves, potentially driving unhealthy eating behaviors and contributing to obesity.
- Nutrition and Health
Is Malnutrition Associated With Crowding In Permanent Dentition
This study found that poor childhood nutrition (stunted growth) may contribute to crowded teeth, but only in adolescents who habitually breathe through their mouth.
- Environment and Health
Is Meat Eating Morally Defensible Contemporary Ethical Considerations
This research examines the ethical debate around eating meat, considering animal welfare, environmental impact, and health factors as people increasingly question whether meat consumption is morally justified.
- Heart Health
Is Pathologic Intimal Thickening The Key To Understanding Early Plaque Progression In Human Atherosclerotic Disease
Researchers are studying how the earliest stages of artery wall thickening may hold the key to understanding how heart disease develops and progresses over time.
- Evolutionary Health and Aging
Is The Sardinian Blue Zone The New Shangri La For Mental Health Evidence On Depressive Symptoms And Its Correlates In Late Adult Life Span
Older adults living in Sardinia's Blue Zone—an area known for exceptional longevity—showed fewer signs of depression, especially when they gardened regularly and felt physically healthy.
- Nutrition and Health
Is There Such A Thing As “Anti Nutrients” A Narrative Review Of Perceived Problematic Plant Compounds
This review examines whether "anti-nutrients" in plant foods like lectins and oxalates are actually harmful, finding that the benefits of eating plants far outweigh any potential risks.
- Nutrition and Health
Is There Such A Thing As “Anti Nutrients” A Narrative Review Of Perceived Problematic Plant Compounds
This review examines whether "anti-nutrients" in plants like lectins and oxalates are actually harmful, finding that the health benefits of plant foods far outweigh these concerns.
- Brain and Nerve Health
Islamic Fasting And Multiple Sclerosis
Research suggests that Ramadan fasting may be safe for most stable multiple sclerosis patients, though symptoms like fatigue may temporarily worsen during fasting periods.
- Liver and Kidney Health
Isolation And Characterization Of Cells Resistant To ML236B (compactin) With Increased Levels Of 3 Hydroxy 3 Methylglutaryl Coenzyme A Reductase
Researchers discovered how cells can develop resistance to cholesterol-lowering drugs by dramatically increasing production of a key enzyme that makes cholesterol.
- Gut Health
Isolation And Characterization Of Human Intestinal Bacteria Capable Of Transforming The Dietary Carcinogen 2 Amino 1 Methyl 6 Phenylimidazo[4,5 B]Pyridine
Researchers found that gut bacteria can transform a cancer-causing chemical from cooked meat, but this process may create a different harmful compound instead of safely eliminating it.
- Liver and Kidney Health
Isolation And Functional Interrogation Of Adult Human Prostate Epithelial Stem Cells At Single Cell Resolution
Researchers developed a new method to identify and study stem cells in the human prostate, discovering unique characteristics that help maintain prostate health throughout life.
- Evolutionary Health and Aging
Isotope Data From Amino Acids Indicate Darwin’s Ground Sloth Was Not An Herbivore
Scientists discovered that giant ground sloths from the Ice Age weren't vegetarians as previously thought, but likely ate meat by scavenging carcasses.
- Evolutionary Health and Aging
Isotopic Evidence For An Early Shift To C4 Resources By Pliocene Hominins In Chad
Ancient human ancestors in Africa shifted to eating grasses and plants that use a different type of photosynthesis over 3 million years ago, changing their metabolism and allowing them to survive in new environments.
- Evolutionary Health and Aging
Isotopic Evidence For The Diets Of European Neanderthals And Early Modern Humans
Neanderthals ate only large animals like mammoths, while early modern humans had more varied diets including fish, which may have contributed to their evolutionary success.
- Heart Health
JACC Focus Seminar Framingham Heart Study
The Framingham Heart Study, launched in 1948, became the longest-running research project tracking heart disease causes and risk factors across multiple generations of families.
Disclaimer: this library, including every summary, is for general informational and educational purposes only. It does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before changing your diet, exercise, or health regimen, or if you have questions about a medical condition.