Metabolic
Library
1,810 peer-reviewed papers, each with a plain-language summary and the source document. The evidence behind the VALIA method, kept where you can read it.
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1,810 papers
· 13 topics
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1,810 results · page 18 of 38
- Heart Health
Hypercholesterolemia During Weight Loss On High Fat Low Carb Diets
A study found that people on high-fat, low-carb diets lost the same amount of weight as those on low-fat diets, but experienced increases in LDL ("bad") cholesterol levels.
- Heart Health
Hyperglycemia Induces Trained Immunity In Macrophages And Their Precursors And Promotes Atherosclerosis
Researchers discovered that high blood sugar "trains" immune cells to stay in an inflammatory state that promotes heart disease, even after blood sugar returns to normal.
- Heart Health
Hyperinsulinemia As Independent Risk Factor For Heart Disease
This study found that men with higher insulin levels in their blood had a significantly increased risk of developing heart disease, even after accounting for other risk factors.
- Heart Health
Hyperlipidemia Is The Compensatory Response To The Utilization Rate Decrease Of Nutrients Lipids Are Not The Culprit
This research challenges the common view that high cholesterol is harmful, arguing instead that elevated blood lipids serve important protective functions in the body.
- Heart Health
Hypertension Aggravates Atherosclerosis A Matter Of Pressure Remodeling Of Myofibroblasts Or LDL Accumulation
Researchers debate whether high blood pressure damages arteries through pressure itself or through increased blood flow, which could change how we treat hypertension.
- Brain and Nerve Health
Hypometabolism, Alzheimer’s Disease, And Possible Therapeutic Targets An Overview (1)
Research shows that reduced brain energy metabolism may actually cause Alzheimer's disease rather than just being a result of it, suggesting new treatment approaches.
- Heart Health
Hypoxia Induced Vascular Endothelial Growth Factor Expression Precedes Neovascularization After Cerebral Ischemia
Researchers found that after a stroke, the brain naturally tries to heal itself by growing new blood vessels to restore oxygen flow to damaged areas.
- Environment and Health
Identification Of A Metabolomic Signature Associated With Feed Efficiency In Beef Cattle
Scientists identified blood markers that can predict which cattle convert food to meat most efficiently, potentially reducing environmental impact of livestock farming.
- Nutrition and Health
Identification Of Biomarkers For Intake Of Protein From Meat, Dairy Products And Grains A Controlled Dietary Intervention Study
Researchers identified specific amino acids in blood and urine that can accurately predict whether someone has been eating high amounts of meat or grain protein.
- Evolutionary Health and Aging
Identification Of Differences In Human And Great Ape Phytanic Acid Metabolism That Could Influence Gene Expression Profiles And Physiological Functions
Researchers discovered that great apes naturally produce higher levels of a plant-derived fatty acid called phytanic acid than humans, which may affect metabolism and health.
- Hormone Health
If You Can T Beat It–Use It Why And How Clinicians Need To Consider Social Media In The Treatment Of Adolescents With Obesity
Social media food marketing significantly influences teenage eating habits and weight gain, suggesting doctors should address social media exposure when treating adolescent obesity.
- Joint, Muscle Health and Exercise
Impact Of A 6 Week Non Energy Restricted Ketogenic Diet On Physical Fitness, Body Composition And Biochemical Parameters In Healthy Adults
A 6-week ketogenic diet in healthy adults caused modest weight loss and improved insulin levels, but slightly reduced endurance performance while not affecting daily activities.
- Hormone Health
Impact Of A Ketogenic Diet On Metabolic Parameters In Patients With Obesity Or Overweight And With Or Without Type 2 Diabetes A Meta Analysis Of Randomized Controlled Trials
A comprehensive review of 14 studies found that ketogenic diets are more effective than low-fat diets for improving blood sugar, weight loss, and cholesterol levels, especially in people with diabetes.
- Liver and Kidney Health
Impact Of A Very Low Calorie Ketogenic Diet (VLCKD) On Changes In Handgrip Strength In Women With Obesity
A very low-calorie ketogenic diet helped women with obesity maintain muscle strength (measured by grip strength) while losing weight and reducing inflammation.
- Evolutionary Health and Aging
Impact Of Carnivory On Human Development And Evolution Revealed By A New Unifying Model Of Weaning In Mammals
This study found that eating meat allowed early human ancestors to wean their babies earlier than other primates, leading to faster reproduction and evolutionary advantages.
- Heart Health
Impact Of Cholesterol On Membrane Mobility
Researchers discovered that cholesterol affects cell membrane flexibility in complex ways that depend on the specific types of fats in the membrane.
- Nutrition and Health
Impact Of Maternal Nutrition On Breast Milk Co 2016 The American Journal Of
This study found that what breastfeeding mothers eat does affect their breast milk's nutritional content, but the research on this topic is surprisingly limited.
- Joint, Muscle Health and Exercise
Impact Of Pre Exercise Feeding Status On Metabolic Adaptations To Endurance Type Exercise Training
Eating carbohydrates before exercise training may reduce some of the metabolic benefits that exercise provides for blood sugar control and insulin sensitivity.
- Joint, Muscle Health and Exercise
Impact Of Pre Exercise Feeding Status On Metabolic Adaptations To Endurance Type Exercise Training(1)
Exercising before eating (in a fasted state) may lead to better metabolic improvements from endurance training compared to exercising after eating carbohydrates.
- Gut Health
Impact Of Red And Processed Meat And Fibre Intake On Treatment Outcomes Among Patients With Chronic Inflammatory Diseases Protocol For A Prospective Cohort Study Of Prognostic Factors And Personalised Medicine
Researchers are studying how eating red meat, processed meat, and fiber affects treatment success in patients with chronic inflammatory diseases like Crohn's disease and rheumatoid arthritis.
- Environment and Health
Impact Of The Healthy Foods North Nutrition Intervention Program On Inuit And Inuvialuit Food Consumption And Preparation Methods In Canadian Arctic Communities
A 12-month nutrition program successfully helped Inuit and Inuvialuit communities in Arctic Canada reduce unhealthy food consumption and adopt healthier cooking methods.
- Liver and Kidney Health
Impaired Ketogenesis And Increased Acetyl CoA Oxidation Promote Hyperglycemia In Human Fatty Liver
Researchers found that fatty liver disease disrupts the liver's ability to produce ketones during fasting, which may contribute to high blood sugar levels.
- Heart Health
Implications Of Changing National Cholesterol Education Program Goals For The Treatment And Control Of Hypercholesterolemia
This study found that when cholesterol treatment guidelines became stricter in the early 2000s, millions more Americans needed cholesterol-lowering medications to reach their target levels.
- Evolutionary Health and Aging
Implications Of Natural Selection In Shaping 99.4 Nonsynonymous DNA Identity Between Humans And Chimpanzees Enlarging Genus Homo
Scientists found that humans and chimpanzees share 99.4% identical DNA in functionally important genes, suggesting we're so closely related that some propose classifying chimps in the human genus.
- Heart Health
Improving Growth Of Infants With Congenital Heart
A specialized nutrition support program helped infants born with heart defects grow better and recover faster after heart surgery.
- Heart Health
In Celebration Of The 100th Anniversary Of The Lipid Hypothesis Of Atherosclerosis
This article celebrates the 100th anniversary of groundbreaking 1913 research that first identified cholesterol as the key substance causing hardened arteries and heart disease.
- Liver and Kidney Health
Incidence And Characteristics Of Kidney Stones In Patients On Ketogenic Diet A Systematic Review And Meta Analysis
This research study examined how often people following ketogenic (very low-carb) diets develop kidney stones and what types of stones they get.
- Gut Health
Incidence And Treatment Of Patients Diagnosed With
A Swedish study found that nearly 1 in 4 people diagnosed with inflammatory bowel disease (IBD) are 60 or older, and they experience different treatment patterns than younger patients.
- Gut Health
Incidence And Treatment Of Patients Diagnosed With Inflammatory Bowel Diseases At 60 Years Or Older In SwedenIncidence And Treatment Of Patients Diagnosed With Inflammatory Bowel Diseases At 60 Years Or Older In Sweden
A Swedish study found that nearly 1 in 4 people diagnosed with inflammatory bowel disease (IBD) are 60 or older, and these older patients require more hospitalizations but use fewer advanced medications.
- Heart Health
Incidence Of Atherosclerosis In Radial Arteries Of Cadavers
Researchers examined arteries from cadavers and found that radial arteries (in the forearm) rarely develop significant blockages, making them good candidates for heart bypass surgery.
- Heart Health
Increase In LDL On LCD
People with normal weight may see their LDL ("bad") cholesterol rise significantly on low-carb diets, while heavier individuals typically see it stay the same or decrease.
- Joint, Muscle Health and Exercise
Increased Adipose Tissue Oxygen Tension In Obese Compared With Lean Men Is Accompanied By Insulin Resistance, Impaired Adipose Tissue Capillarization, And Inflammation
Researchers found that obese men have higher oxygen levels in fat tissue than lean men, but this isn't healthy—it's linked to inflammation and insulin resistance.
- Joint, Muscle Health and Exercise
Increased Adipose Tissue Oxygen Tension In Obese Compared With Lean Men Is Accompanied By Insulin Resistance, Impaired Adipose Tissue Capillarization, And Inflammation(1)
Researchers found that obese men have higher oxygen levels in their fat tissue than lean men, which is linked to inflammation and insulin resistance.
- Nutrition and Health
Increased Advanced Glycation End Product And Meat Consumption Is Associated With Childhood Wheeze Analysis Of The National Health And Nutrition Examination Survey
A large study found that children who eat more cooked meat and foods high in harmful compounds called AGEs are more likely to experience wheezing and breathing problems.
- Nutrition and Health
Increased Fat Catabolism Sustains Water Balance During Fasting In Zebra Finches
Research on zebra finches revealed that when fasting without water access, birds primarily burn fat rather than protein to generate the water their bodies need to survive.
- Nutrition and Health
Increased Fat Free Body Mass And No Adverse Effects On Blood Lipid Concentrations 4 Weeks After Additional Meat Consumption In Comparison With An Exclusion Of Meat In The Diet Of Young Healthy Women
Adding lean meat to young women's diets for 4 weeks increased muscle mass without raising cholesterol levels, while removing meat decreased muscle mass.
- Nutrition and Health
Increased Risk Of Iodine Deficiency With Vegetarian Nutrition
A small study found that people following strict vegetarian diets without iodized salt had significantly lower iodine levels, potentially putting them at risk for iodine deficiency.
- Nutrition and Health
Increasing Food Acceptance In The Home Setting A Rand 2012 The American Jou
Giving children small stickers as rewards while repeatedly offering tastes of disliked vegetables successfully increased their vegetable intake and preference at home.
- Liver and Kidney Health
Incretin Hormones The Link Between Glycemic Index And Cardiometabolic Diseases
This research explores how incretin hormones (natural gut hormones) may explain why low glycemic index foods reduce the risk of diabetes and heart disease.
- Liver and Kidney Health
Independent Effect Of Vitamin B12 Deficiency On Hematological Status In Older Chinese Vegetarian Women
A study of older vegetarian women found that vitamin B12 deficiency was very common and caused lower blood counts, even without the typical signs doctors usually look for.
- Nutrition and Health
Induction Of Ketosis In Rats Fed Low Carbohydrate, High Fat Diets Depends On The Relative Abundance Of Dietary Fat And Protein
This rat study found that low-carb, high-fat diets only trigger ketosis (fat burning for energy) when fat makes up at least 65% of calories, with protein kept low.
- Brain and Nerve Health
Inflammation But Not Glycemic Control Is Associated With Neurocognitive Decline After Cardiac Surgery
After heart surgery, inflammation markers predicted cognitive decline better than blood sugar control, suggesting inflammation may be more important for protecting brain function.
- Mental Health
Inflammation Causes Mood Changes Through Alterations In Subgenual Cingulate Activity And Mesolimbic Connectivity
Researchers found that inflammation in the body can directly cause mood changes and depression by altering brain activity in regions that control emotions.
- Heart Health
Inflammation CVD
New research suggests that inflammation, not cholesterol levels, may be the primary driver of heart disease and other chronic conditions.
- Heart Health
Inflammation In Metabolic Cardiomyopathy
This research explains how chronic inflammation from obesity and diabetes damages the heart muscle, leading to a specific type of heart disease called metabolic cardiomyopathy.
- Gut Health
Influence Of Bariatric Surgery On Gut Microbiota Composition And Its Implication On Brain And Peripheral Targets
Bariatric surgery works not just by restricting food intake, but by changing gut bacteria in ways that reduce food cravings and improve metabolism through brain and hormone changes.
- Evolutionary Health and Aging
Influence Of Diet On Leukocyte Telomere Length, Markers Of Inflammation And Oxidative Stress In Individuals With Varied Glucose Tolerance A Chinese Population Study
This Chinese study found that eating legumes, nuts, fish, and seaweed helps protect telomeres (cellular aging markers), while sugary drinks accelerate telomere shortening in people with varying blood sugar levels.
- Brain and Nerve Health
Influence Of Dietary Patterns In The Pathophysiology Of Huntington S Disease A Literature Review
Researchers reviewed how different eating patterns like Mediterranean, ketogenic, and plant-based diets might help slow the progression of Huntington's disease, a rare brain disorder.
Disclaimer: this library, including every summary, is for general informational and educational purposes only. It does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before changing your diet, exercise, or health regimen, or if you have questions about a medical condition.