Metabolic
Library
1,810 peer-reviewed papers, each with a plain-language summary and the source document. The evidence behind the VALIA method, kept where you can read it.
Educational information only. Not medical advice, diagnosis or treatment. For anything about your own health, speak with a clinician. To become a patient, start at our contact page.
1,810 papers
· 13 topics
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1,810 results · page 17 of 38
- Nutrition and Health
Health Effects Of Dietary Risks In 195 Countries,
This large global study found that poor dietary choices are a major preventable cause of heart disease, diabetes, and other chronic diseases worldwide.
- Heart Health
Health Effects Red Meat
This research examines conflicting evidence about red meat's health risks and calls for better methods to determine safe consumption levels.
- Heart Health
Health Effects Red Meat 1
Researchers are working to clarify conflicting evidence about how red meat consumption affects health risks and mortality.
- Nutrition and Health
Health Promoting Phytonutrients Are Higher In Grass Fed Meat And Milk
Grass-fed meat and dairy contain significantly higher levels of beneficial plant compounds called phytonutrients compared to grain-fed animal products.
- Nutrition and Health
Health Risk Factors Associated With Meat, Fruit And Vegetable Consumption In Cohort Studies A Comprehensive Meta Analysis
This large research review found that people who eat more red meat tend to have unhealthier lifestyle habits, while those eating more fruits and vegetables have healthier behaviors overall.
- Dental Health
Healthy Food, Healthy Teeth A Formative Study To Assess Knowledge Of Foods For Oral Health In Children And Adults
A study found that both children and adults correctly identify high-sugar foods as bad for teeth, but many don't realize that refined carbohydrates recommended in dietary guidelines can also cause tooth decay.
- Heart Health
Heart Disease And Single Vitamin Supple 2007 The American Journal Of Clinica
This research review found that vitamin E supplements alone cannot reverse poor diet and lifestyle habits to prevent heart disease, despite the vitamin's antioxidant properties.
- Heart Health
Heart Dz Prevalance
Heart disease affects about 5-6% of American adults, with rates increasing dramatically with age and being nearly twice as high in men compared to women.
- Joint, Muscle Health and Exercise
Heart Rate Variability And Fatty Acid Content Of Blo 1999 The American Journ
This study found that omega-3 fatty acid supplements improved heart rhythm patterns in healthy men, potentially reducing their risk of sudden cardiac death.
- Joint, Muscle Health and Exercise
Heart Rate Variability And Fatty Acid Content Of Blo 1999 The American Journ(1)
This study found that omega-3 fatty acid supplements improved heart rhythm regulation in healthy men, potentially reducing their risk of sudden cardiac death.
- Hormone Health
Hedonic Eating And The “Delicious Circle” From Lipid Derived Mediators To Brain Dopamine And Back
This research explores how eating delicious, high-fat foods creates a brain reward cycle that can lead to overeating beyond what our body needs for energy.
- Heart Health
Hepatic Effects In Beagle Dogs Administered Atorvastatin, A 3 Hydroxy 3 Methylglutaryl Coenzyme A Reductase Inhibitor, For 2 Years
This study found that high doses of atorvastatin (Lipitor) caused reversible liver damage in dogs, while effectively lowering cholesterol levels.
- Liver and Kidney Health
Hepatic Steatosis, Inflammation, And ER Stress In Mice Maintained Long Term On A Very Low Carbohydrate Ketogenic Diet
Researchers found that mice on long-term ketogenic diets developed fatty liver disease and liver inflammation, despite staying lean and maintaining normal insulin sensitivity.
- Heart Health
Hibiscus Sabdariffa L Tea Tisane Lowers Blood Pressure 2010 The Journal
Drinking hibiscus tea daily for six weeks significantly lowered blood pressure in adults with pre-hypertension and mild high blood pressure.
- Nutrition and Health
High Added Sugars Intake Among US Adults Characteristics, Eating Occasions, And Top Sources, 2015–2018
A CDC study found that 30% of US adults consume dangerously high levels of added sugars (over 15% of daily calories), with younger adults and those with less education at highest risk.
- Heart Health
High Consumption Of Ultra Processed Food Is Associated With 2021 The Journal
Older adults who ate the most ultra-processed foods were more than twice as likely to develop unhealthy cholesterol levels compared to those who ate the least.
- Nutrition and Health
High Dietary Niacin Intake Is Associated With Decreased Chromosome Translocation Frequency In Airline Pilots
A study of airline pilots found that those who ate more niacin (vitamin B3) from food had less DNA damage from radiation exposure.
- Liver and Kidney Health
High Fat Diet Induced Kidney Alterations In Rats With Metabolic Syndrome Endothelial Dysfunction And Decreased Antioxidant Defense
A high-fat diet damages kidney blood vessels and reduces antioxidant defenses before kidney function declines, but vitamin B6 treatment may help protect against this damage.
- Nutrition and Health
High Folate And Low Vitamin B 12 Intakes During Pregnancy 2013 The American
A study found that pregnant women taking high folic acid supplements while having low vitamin B12 intake had higher rates of underweight babies.
- Heart Health
High Glucose Attenuates Shear Induced Changes In Endothelial Hydraulic Conductivity By Degrading The Glycocalyx
High blood sugar damages the protective lining of blood vessels, making them less responsive to blood flow and potentially explaining why diabetics develop heart disease differently.
- Nutrition and Health
High Glycemic Index And Glycemic Load Diets As Risk 2020 The American Journ
A large study of postmenopausal women found that diets high in refined carbohydrates and foods that spike blood sugar were linked to higher rates of insomnia.
- Skin and Hair Health
High Glycemic Load Diet, Milk And Ice Cream Consumption Are Related To Acne Vulgaris In Malaysian Young Adults A Case Control Study
A study of Malaysian young adults found that people with acne consumed more high blood sugar-spiking foods, milk, and ice cream compared to those without acne.
- Brain and Nerve Health
High Low Density Lipoprotein Cholesterol Inversely Relates To Dementia In Community Dwelling Older Adults The Shanghai Aging Study
A study of nearly 4,000 older Chinese adults found that higher levels of "bad" LDL cholesterol were actually associated with lower rates of dementia.
- Liver and Kidney Health
High Plasma SRAGE (Soluble Receptor For Advanced Glycation End Products) Is Associated With Slower Carotid Intima Media Thickness Progression And Lower Risk For First Time Coronary Events And Mortality
Higher levels of a protective protein called sRAGE in the blood are linked to slower artery thickening and lower risk of heart disease and death.
- Liver and Kidney Health
High Plasma Uric Acid Concentration Causes And Consequences
High uric acid levels in blood can either protect against cell damage or increase disease risk, depending on whether the elevation is temporary or chronic.
- Liver and Kidney Health
High Protein Diet With Renal Hyperfiltration Is Associated With Rapid Decline Rate Of Renal Function A Community Based Prospective Cohort Study
High protein diets may accelerate kidney function decline, especially in people whose kidneys are already working harder than normal to filter blood.
- Nutrition and Health
Higher Childhood Red Meat Intake Frequency Is Associate 2016 The Journal Of
Girls who ate red meat twice daily during childhood started their first menstrual period earlier than those who ate it less than four times per week.
- Gut Health
Higher Free Triiodothyronine Is Associated With Non Alcoholic Fatty Liver Disease In Euthyroid Subjects The Lifelines Cohort Study
Higher levels of the thyroid hormone T3 are linked to fatty liver disease, even in people with normal thyroid function.
- Brain and Nerve Health
Higher Ketogenic Diet Ratios Confer Protection From Seizures Without Neurotoxicity
Researchers found that higher-fat ketogenic diets (6:1 ratio) provided better seizure protection than standard ketogenic diets (4:1 ratio) without causing brain damage.
- Brain and Nerve Health
Higher Non Processed Red Meat Consumption Is Associated With A Reduced Risk Of Central Nervous System Demyelination
A large Australian study found that people who ate more unprocessed red meat (like steak and ground beef) had a lower risk of developing multiple sclerosis-like brain conditions.
- Liver and Kidney Health
Hmgcs2 Mediated Ketogenesis Modulates High Fat Diet Induced Hepatosteatosis
Researchers found that boosting the liver's ability to produce ketones can help prevent and treat fatty liver disease caused by high-fat diets.
- Evolutionary Health and Aging
Homo Erectus Adapted To Steppe Desert Climate Extremes One Million Years Ago
New research shows that early human ancestors (Homo erectus) successfully adapted to extreme desert environments one million years ago, demonstrating remarkable flexibility in surviving harsh conditions.
- Heart Health
Homocysteine, Vitamins B6 And Folic Acid In Experimental Models Of Myocardial Infarction And Heart Failure—How Strong Is That Link
This research explores how elevated homocysteine (an amino acid in blood) may contribute to heart attacks and heart failure, and whether B vitamins could help protect heart health.
- Heart Health
Homocysteine, Vitamins B6 And Folic Acid In Experimental Models Of Myocardial Infarction And Heart Failure—How Strong Is That Link
This research explores how high levels of homocysteine (an amino acid in blood) may contribute to heart attacks and heart failure, and whether B vitamins could help protect the heart.
- Skin and Hair Health
Hormonal And Dietary Factors In Acne Vulgaris Versus Controls
Researchers found that people with acne are more likely to have vitamin D deficiency and positive blood markers suggesting gluten sensitivity.
- Gut Health
How Autophagy Controls The Intestinal Epithelial Barrier
Autophagy, the body's cellular recycling system, plays a crucial role in maintaining the intestinal barrier that protects us from harmful substances and supports gut health.
- Heart Health
How Cholesterol Interacts With Proteins And L 2015 Biochimica Et Biophysica
This research explains how cholesterol moves around inside cells through complex interactions with proteins and other fats, which is essential for proper cell membrane function.
- Nutrition and Health
How Does The Health And Well Being Of Young Australian Vegetarian And Semi Vegetarian Women Compare With Non Vegetarians
A study of young Australian women found that vegetarians and semi-vegetarians had lower body weight and exercised more, but experienced higher rates of depression and menstrual problems.
- Evolutionary Health and Aging
How Plants Conquered Land Cell
Scientists studied how ancient algae evolved to survive on land 500 million years ago, discovering key adaptations that later enabled all plant and animal life on Earth.
- Evolutionary Health and Aging
Human Adaptations To Diet, Subsistence, And Ecoregion Are Due To Subtle Shifts In Allele Frequency
This study reveals how human genes gradually adapted over thousands of years to help different populations better process specific diets and survive in various climates.
- Gut Health
Human Breast Milk NMR Metabolomic Profile Across Specific Geographical Locations And Its Association With The Milk Microbiota
Researchers found that breast milk composition varies significantly by geographic location and is influenced by the beneficial bacteria present in the milk.
- Gut Health
Human Digestive Physiology And Evolutionary Diet A Metabolomic Perspective On Carnivorous And Scavenger Adaptations
This research examines how human digestion evolved to handle meat-based diets, revealing specific metabolic adaptations that may explain modern dietary responses.
- Gut Health
Human Milk Oligosaccharide Consumption By Intestin
Breast milk contains special sugars that babies can't digest, but these sugars feed beneficial gut bacteria that are crucial for infant health.
- Evolutionary Health and Aging
Human Occupation Of The North American Colorado Plateau ∼37,000 Years Ago
Researchers found evidence that humans lived in North America about 37,000 years ago, much earlier than previously thought, by studying ancient mammoth bones with signs of butchering.
- Joint, Muscle Health and Exercise
Human Relevant Levels Of Added Sugar Consumption Increase Female Mortality And Lower Male Fitness In Mice
A mouse study found that consuming added sugar at levels similar to the typical American diet significantly increased death rates in females and reduced reproductive success in males.
- Joint, Muscle Health and Exercise
Human Relevant Levels Of Added Sugar Consumption Increase Female Mortality And Lower Male Fitness In Mice(1)
A study found that mice consuming added sugar amounts equivalent to typical human intake experienced doubled female death rates and reduced male reproductive success.
- Evolutionary Health and Aging
Human Specific Loss Of Olfactory Receptor Genes
Humans have lost the ability to smell many odors compared to other primates, with 60% of our smell-detecting genes being broken or non-functional.
- Evolutionary Health and Aging
Hunter Gatherers As Models In Public Health
Researchers studied hunter-gatherer populations to understand why they have excellent heart health and almost no obesity, diabetes, or metabolic diseases compared to modern societies.
Disclaimer: this library, including every summary, is for general informational and educational purposes only. It does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before changing your diet, exercise, or health regimen, or if you have questions about a medical condition.