Metabolic
Library
1,810 peer-reviewed papers, each with a plain-language summary and the source document. The evidence behind the VALIA method, kept where you can read it.
Educational information only. Not medical advice, diagnosis or treatment. For anything about your own health, speak with a clinician. To become a patient, start at our contact page.
1,810 papers
· 13 topics
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1,810 results · page 23 of 38
- Environment and Health
Loss Of Grazing By Large Mammalian Herbivores Can Destabilize The Soil Carbon Pool
Large grazing animals like cattle and sheep help keep soil carbon stable, and losing these animals could worsen climate change by releasing stored carbon from soil.
- Heart Health
Loss Of Metabolic Flexibility In The Failing Heart
When the heart fails, it loses its ability to efficiently switch between different fuel sources like fats and sugars, which worsens heart function.
- Heart Health
Lovastatin Decreases Coenzyme Q Levels In Humans
Researchers found that lovastatin, a cholesterol-lowering medication, also reduces levels of coenzyme Q10, a nutrient essential for heart function.
- Hormone Health
Low Carbohydrate Diets In The Management Of Obesity And Type 2 Diabetes A Review From Clinicians Using The Approach In Practice
This review examines how low-carbohydrate diets can effectively help patients manage obesity and type 2 diabetes, with support from international medical guidelines.
- Heart Health
Low Carbohydrate High Protein Diet And Incidence Of Cardiovascular Diseases In Swedish Women Prospective Cohort Study
A large Swedish study found that women following low-carb, high-protein diets for many years had a slightly higher risk of developing heart disease and stroke.
- Nutrition and Health
Low Carbohydrate Nutrition And Metabolism
Research shows that low-carbohydrate diets may help with weight loss and diabetes by changing how the body burns fuel from sugar to fat.
- Heart Health
Low Carbohydrate–high Protein Diets Is There A Place For Them In Clinical Cardiology
This research examines whether low-carb, high-protein diets like Atkins are safe and effective alternatives to traditional low-fat diets for heart health.
- Joint, Muscle Health and Exercise
Low Carbohydrate, High Fat Diet Impairs Exercise Economy And Negates The Performance Benefit From Intensified Training In Elite Race Walkers
Elite athletes following a very low-carb, high-fat diet burned more fat during exercise but became less efficient, requiring more oxygen and ultimately performing worse despite improved fitness.
- Heart Health
Low Cholesterol Is Associated With Mortality From Cardiovascular Diseases A Dynamic Cohort Study In Korean Adults
A Korean study found that both very low cholesterol (under 160 mg/dL) and very high cholesterol (240+ mg/dL) were linked to higher heart disease death rates.
- Liver and Kidney Health
Low Density Lipoprotein Receptor And 3 Hydroxy 3 Methylglutaryl Coenzyme A Reductase Gene Expression In Human Mononuclear Leukocytes Is Regulated Coordinately And Parallels Gene Expression In Human Liver
This study found that white blood cells can be used to measure cholesterol regulation activity, potentially offering a less invasive way to assess liver metabolism than liver biopsies.
- Heart Health
Low Dose 1,3 Butanediol Reverses Age Associated Vascular Dysfunction Independent Of Ketone Body β Hydroxybutyrate
Researchers found that low doses of a compound called 1,3-butanediol can restore healthy blood vessel function in aging rats without producing ketones.
- Brain and Nerve Health
Low Fat Versus Ketogenic Diet In Parkinson S Disease A Pilot Randomized Controlled Trial
A small study found that both low-fat and ketogenic diets helped Parkinson's disease symptoms, but the ketogenic diet provided greater improvements in non-movement symptoms like fatigue and sleep problems.
- Brain and Nerve Health
Low Fat Versus Ketogenic Diet In Parkinson’s Disease A Pilot Randomized Controlled Trial
A small study found that both low-fat and ketogenic diets helped Parkinson's disease symptoms, but the ketogenic diet provided greater improvements in non-movement symptoms like fatigue and sleep problems.
- Brain and Nerve Health
Low Fat Vs Keto For Parkinsons
A small study found that both low-fat and ketogenic diets improved Parkinson's disease symptoms over 8 weeks, with the ketogenic diet showing greater benefits for non-movement symptoms.
- Heart Health
Low Lipoprotein(a) Concentration Is Associated With Cancer And All Cause Deaths A Population Based Cohort Study
A large Japanese study found that people with very low levels of lipoprotein(a), a type of cholesterol particle, had higher rates of cancer and death from all causes.
- Nutrition and Health
Low Phytate Wholegrain Bread Instead Of High Phytate Wholegrain Bread In A Total Diet Context Did Not Improve Iron Status Of Healthy Swedish Females A 12 Week, Randomized, Parallel Design Intervention Study
A study found that eating whole grain bread with less phytate (a compound that blocks iron absorption) surprisingly worsened iron levels in healthy women compared to regular whole grain bread.
- Nutrition and Health
Low Tissue Creatine A Therapeutic Target In Clinical Nutrition
Low levels of creatine (a natural energy compound) in body tissues may be a key indicator and treatment target for various diseases including brain, heart, and metabolic disorders.
- Nutrition and Health
LowCarb For USA
Leading nutrition researchers argue that low-carbohydrate diets should be considered as alternative dietary approaches for Americans, especially given rising rates of obesity and diabetes.
- Heart Health
Lower Lifetime Dietary Fiber Intake Is Associated With 2012 The American Jou
People who ate less fiber throughout their teens and twenties had stiffer, less healthy arteries by age 36, suggesting fiber protects heart health from a young age.
- Liver and Kidney Health
Lowering Urinary Oxalate Excretion To Decrease Calcium Oxalate Stone Disease
Dietary changes, particularly avoiding high-oxalate foods and maintaining proper calcium intake, can help prevent calcium oxalate kidney stones by reducing oxalate levels in urine.
- Heart Health
LowFat Ideology
This historical analysis reveals how low-fat diet recommendations became widespread in America despite lacking strong evidence for preventing heart disease or promoting weight loss.
- Heart Health
LpA II B C D E A New Immunochemically Defined Acute Phase Lipoprotein In Humans
Researchers discovered a new type of cholesterol particle that increases during inflammation and may help the body fight infections and heal damaged tissues.
- Environment and Health
Lymphangiogenesis Fuel, Smoke, Or Extinguisher Of Inflammation’s Fire
Researchers are studying whether the growth of new lymphatic vessels during inflammation helps heal the body or makes inflammatory conditions worse.
- Liver and Kidney Health
Lysosomal Acid Lipase As A Molecular Target Of The Very Low Carbohydrate Ketogenic Diet In Morbidly Obese Patients The Potential Effects On Liver Steatosis And Cardiovascular Risk Factors
A very low-carb ketogenic diet for 25 days helped severely obese patients lose weight, improve liver fat buildup, and boost activity of an enzyme that breaks down fats.
- Heart Health
Lysosomal Acid Lipase As A Molecular Target Of The Very Low Carbohydrate Ketogenic Diet In Morbidly Obese Patients The Potential Effects On Liver Steatosis And Cardiovascular Risk Factors
A very low-carb ketogenic diet for 25 days helped severely obese patients lose weight, improve liver health, and boost activity of an important fat-processing enzyme.
- Nutrition and Health
Macronutrient Composition Of The Diet And Long Ter
A 12-year Italian study found that eating more protein led to weight and waist gain, while replacing sugars with starches helped people maintain healthier weights.
- Heart Health
Macrophages In Cardiovascular Disease
This research review explains how immune cells called macrophages both cause heart damage through inflammation and help hearts heal after injury.
- Mental Health
Magnesium In Prevention And Therapy
Magnesium, the fourth most abundant mineral in your body, is essential for over 300 bodily processes and low levels are linked to chronic diseases like diabetes, heart disease, and neurological disorders.
- Nutrition and Health
Magnesium In Prevention And Therapy
Magnesium is essential for over 300 body processes and low levels are linked to chronic diseases like diabetes, heart disease, and Alzheimer's.
- Dental Health
Malnutrition And Its Oral Outcome – A Review
Poor nutrition and oral health problems create a harmful cycle where malnutrition damages teeth and gums, while dental issues make it harder to eat well.
- Evolutionary Health and Aging
Mammal Species Occupy Different Climates Following The Expansion Of Human Impacts
Human activities have forced two-thirds of mammal species to live in different climates than they occupied before the Industrial Revolution, favoring smaller generalist animals over larger specialized ones.
- Environment and Health
Mammalian Intestinal Allometry, Phylogeny, Trophic Level And Climate
Scientists studied how intestine length varies across 519 mammal species and found that plant-eaters have longer large intestines while animals in colder climates have longer small intestines.
- Evolutionary Health and Aging
Man The Fat Hunter The Demise Of Homo Erectus And The Emergence Of A New Hominin Lineage In The Middle Pleistocene (ca. 400 Kyr) Levant
Scientists propose that ancient humans evolved to become better hunters when large elephants disappeared, forcing them to hunt smaller animals while maintaining their need for dietary fat.
- Heart Health
Markedly Increased Intake Of Refined Carbohydrates And Sugar Is Associated With The Rise Of Coronary Heart Disease And Diabetes Among The Alaskan Inuit
A study of Alaskan Inuit people found that switching from their traditional low-sugar diet to a Western diet high in refined carbohydrates increased their rates of heart disease and diabetes.
- Joint, Muscle Health and Exercise
Maternal Exercise Intergenerationally Drives Muscle Based Thermo 2022 EBioMe
Exercise during pregnancy can improve muscle metabolism in children by activating genes that help muscles burn calories more efficiently, even protecting against inherited effects of maternal obesity.
- Joint, Muscle Health and Exercise
Maternal Exercise Intergenerationally Drives Muscle Based Thermo 2022 EBioMe(1)
Exercise during pregnancy can improve the ability of children's muscles to burn calories and maintain healthy metabolism, even protecting against obesity later in life.
- Nutrition and Health
Maternal Supplementation Differentially Affects The M 2010 The Journal Of Nu
A long-term study found that nutritional supplements during pregnancy improved baby birth weight, with energy content being more important than protein.
- Nutrition and Health
Meal Frequency And Timing In Health And Disease
Research suggests that eating less frequently and taking breaks from eating for 16+ hours may improve health by shifting the body to burn fat and activate cellular repair processes.
- Nutrition and Health
Meal Timing And Macronutrient Composition Modulate Human Metabolism And Reward Related Drive To Eat
This study found that when you eat during the day and what types of foods you consume both affect your metabolism and how much you crave food.
- Mental Health
Measurement Of The Effect Of Physical Exercise On The Concentration Of Individuals With ADHD
A 5-minute intense running exercise improved attention and concentration in children with ADHD by over 30%, bringing their performance nearly equal to children without ADHD.
- Heart Health
Meat Intake And Cause Specific Mortality
A large Asian study found that meat consumption was not linked to higher death rates, unlike studies in Western populations.
- Evolutionary Health and Aging
Meat Matters Making The Case For A Valuable Food In A Hostile Environment
This scientific review argues that meat has been unfairly vilified and remains a valuable, nutrient-dense food despite growing pressure to eliminate it from diets.
- Heart Health
Mechanism Of Calcification In Cardiovascular Diseases
Researchers studied how calcium deposits form in heart arteries and tissues, which can make blood vessels stiff and increase heart disease risk.
- Joint, Muscle Health and Exercise
Mechanism Of Reduced Muscle Atrophy Via Ketone Body (D) 3 Hydroxybutyrate
Researchers found that 3-hydroxybutyrate, a ketone produced during fasting or low-carb diets, may help prevent muscle loss by improving protein balance and cellular metabolism.
- Heart Health
Mechanisms And Clinical Consequences Of Vascular Calcification
Calcium buildup in blood vessels is not just passive aging but an active, bone-like process that significantly increases heart attack and stroke risk.
- Heart Health
Mechanisms Of Oxidized LDL Mediated Endothelial Dysfunction And Its Consequences For The Development Of Atherosclerosis
This research explains how damaged "bad" cholesterol (oxidized LDL) harms blood vessel walls and drives the development of atherosclerosis, the underlying cause of heart attacks and strokes.
- Mental Health
Media Addiction In A 10 Year Old Boy.24
A case study examines a 10-year-old boy with severe behavioral problems worsened by excessive screen time and media use.
- Heart Health
Medial Injury Dysfunction Induced Granulation Tissue Repair Is The Pathogenesis Of Atherosclerosis
Researchers propose that atherosclerosis (artery hardening) begins when the middle layer of artery walls gets damaged, triggering a repair process that actually creates the dangerous plaques.
Disclaimer: this library, including every summary, is for general informational and educational purposes only. It does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before changing your diet, exercise, or health regimen, or if you have questions about a medical condition.