Metabolic
Library
1,810 peer-reviewed papers, each with a plain-language summary and the source document. The evidence behind the VALIA method, kept where you can read it.
Educational information only. Not medical advice, diagnosis or treatment. For anything about your own health, speak with a clinician. To become a patient, start at our contact page.
1,810 papers
· 13 topics
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1,810 results · page 22 of 38
- Heart Health
LDL And CV Dz
Researchers found that having "normal" LDL cholesterol levels doesn't always protect against heart attacks, challenging the common belief that lower cholesterol is always better.
- Gut Health
Leaky Gut And Autoimmunity An Intricate Balance In Individuals Health And The Diseased State
This research explores how "leaky gut" - when the intestinal barrier becomes too permeable - may trigger autoimmune diseases by allowing harmful substances to cross into the bloodstream.
- Heart Health
Lean Mean And Ox Stress
A study found that eating lean red meat instead of some carbs for 8 weeks didn't increase harmful inflammation or oxidative stress in the body.
- Nutrition and Health
Lectin Activity In Commonly Consumed Plant Based Foods Calling For Method Harmonization And Risk Assessment
Researchers tested lectin levels in common plant foods and found that soaking and boiling significantly reduces these potentially harmful proteins, especially in legumes like beans.
- Nutrition and Health
Lectin Based Food Poisoning
Researchers discovered why certain poorly cooked vegetables containing lectins cause food poisoning - these proteins prevent damaged gut cells from repairing themselves.
- Gut Health
Legume Consumption And Gut Microbiome In Elderly Chin 2021 The Journal Of Nu
A study of 2,302 elderly Chinese adults found that eating legumes like peanuts, soy foods, and beans was linked to changes in gut bacteria composition.
- Heart Health
Length Of Residence In The United States Is Associated With A Higher Prevalence Of Cardiometabolic Risk Factors In Immigrants A Contemporary Analysis Of The National Health Interview Survey
Immigrants who live in the US for 10 or more years have higher rates of obesity, diabetes, and high blood pressure than newer immigrants.
- Hormone Health
Leptin Modulates Autophagy In Human CD4+CD25− Conv
Researchers discovered that leptin, a hormone made by fat cells, controls how immune cells recycle their internal components, which affects immune system function.
- Hormone Health
Leptin Resistance And Obesity
Leptin resistance prevents the "satiety hormone" leptin from working properly in most people with obesity, explaining why leptin treatments often fail for weight loss.
- Nutrition and Health
Lessons From Dietary Studies In Adventists An 2003 The American Journal Of C
Research on Seventh-day Adventists reveals that maintaining a lean body weight throughout life is most important for optimal health, while also showing benefits of nuts and potential risks of certain foods.
- Environment and Health
Levelling Foods For Priority Micronutrient Value Can Provide More Meaningful Environmental Footprint Comparisons
Researchers argue that comparing foods' environmental impact should consider their vitamin and mineral content, not just calories or weight, to better guide sustainable eating choices.
- Evolutionary Health and Aging
Life Expectancy Inequalities In The Elderly By Socioeconomic Status Evidence From Italy
Italian researchers found that people with higher socioeconomic status live about 5 years longer after age 60 than those with lower status, even when accounting for other health factors.
- Heart Health
Lifestyle Intervention Reduces Body Weight And Improves Cardiometabolic Risk Factors In Worksites
A workplace wellness program that combined healthy eating guidance with behavior change support helped employees lose an average of 8 pounds and improve their heart health markers.
- Heart Health
Lifetime Cardiovascular Risk Of Childhoo 2010 The American Journal Of Clinic
Childhood obesity significantly increases the risk of developing heart disease later in life due to multiple health complications that damage blood vessels over time.
- Environment and Health
Light And Metabolism In Humans
Modern artificial lighting that disrupts our natural day-night cycle can harm metabolism and increase the risk of obesity and diabetes.
- Environment and Health
Light And Mitochondrial Function
Research shows that red light therapy at 670nm wavelength can improve mitochondrial function and color vision in people over 40.
- Environment and Health
Light Effects On Water Viscosity
Scientists discovered that light can change water thickness inside cellular power plants, potentially explaining how certain light therapies might boost energy production in our cells.
- Environment and Health
Light, Sleep, Cardiometabolic Function
Sleeping with room lights on for just one night can disrupt blood sugar control and increase insulin resistance the following morning.
- Skin and Hair Health
Linking Diet To Acne Metabolomics, Inflammation, And Comedogenesis An Update
This research review explains how Western diet foods like high-sugar carbs, dairy products, and certain fats can trigger acne by disrupting hormones and increasing skin oil production.
- Nutrition and Health
Lipid Droplet Formation Drives Pathogenic Group 2 Innate Lymphoid Cells In Airway Inflammation
Researchers found that a ketogenic diet may help treat certain types of airway inflammation by changing how immune cells process fats and sugars.
- Heart Health
Lipid Energy Model
Researchers propose a new model explaining why some lean people on low-carb diets develop very high cholesterol levels that may not indicate heart disease risk.
- Heart Health
Lipid Keratopathy And Atheroma
Researchers found that fatty deposits in the eye's cornea are similar to fatty plaques in arteries, suggesting both conditions may develop through comparable processes.
- Heart Health
Lipid Lowering Therapy And Hemorrhagic Stroke Risk Comparative Meta Analysis Of Statins And PCSK9 Inhibitors
This large study found that statin medications slightly increase bleeding stroke risk, while newer PCSK9 inhibitor drugs do not carry this same risk.
- Heart Health
Lipid Profiles And All Cause Mortality
A study of Chinese centenarians found that higher total cholesterol levels were associated with lower risk of death, challenging conventional wisdom about cholesterol.
- Heart Health
Lipoic Acid And Cardiovascular Disease 2003 The Journal Of Nutrition
Alpha-lipoic acid (ALA) is a powerful antioxidant that may protect against heart disease by reducing harmful oxidation, improving cholesterol levels, and supporting blood pressure.
- Heart Health
Lipoprotein Lipase Enhances The Binding Of Native And Oxidized Low Density Lipoproteins To Versican And Biglycan Synthesized By Cultured Arterial Smooth Muscle Cells
Researchers found that an enzyme called lipoprotein lipase helps bad cholesterol stick to artery wall proteins, which may worsen plaque buildup and heart disease.
- Liver and Kidney Health
Lipoprotein X Stimulates Monocyte Chemoattractant Protein 1 Expression In Mesangial Cells Via Nuclear Factor κB
Researchers found that an abnormal cholesterol particle called Lipoprotein-X, present in people with a rare genetic condition, triggers kidney inflammation that could lead to kidney damage.
- Nutrition and Health
Lithocholic Acid Phenocopies Anti Ageing Effects Of Calorie Restriction
Scientists discovered that lithocholic acid, a compound naturally produced during calorie restriction, can provide anti-aging benefits like improved muscle strength and longevity without actually restricting calories.
- Skin and Hair Health
Live Imaging Of Wound Angiogenesis Reveals Macrophage Orchestrated Vessel Sprouting And Regression
Scientists discovered that immune cells called macrophages control how new blood vessels grow and disappear during wound healing, which could help treat chronic wounds.
- Environment and Health
Livestock In Evolving Foodscapes And Thoughtscapes
This research examines how human food systems have evolved throughout history and proposes that improving livestock farming practices may be better than eliminating animal foods entirely.
- Brain and Nerve Health
Local Cholesterol Metabolism Orchestrates Remyelination
Researchers found that cholesterol metabolism in brain cells plays a crucial role in repairing the protective coating around nerves, which could lead to new treatments for multiple sclerosis.
- Heart Health
Long Term Calorie Restriction Is Highly Effective In Reducing The Risk For Atherosclerosis In Humans
Long-term calorie restriction significantly reduces heart disease risk by improving cholesterol, blood pressure, and artery health compared to typical American diets.
- Hormone Health
Long Term Effects Of A Ketogenic Diet In Obese Patients
A 24-week study found that obese patients following a ketogenic diet safely lost weight while improving their cholesterol, blood sugar, and other metabolic markers.
- Nutrition and Health
Long Term Effects Of Breastfeeding A Hea 2018 The American Journal Of Clin
Research suggests breastfeeding for up to 12 months may be linked to healthier eating habits in young children, including less sugar-sweetened beverage consumption.
- Liver and Kidney Health
Long Term Effects Of High Protein Diets On Renal Function
This research review examines whether high-protein diets might harm kidney function over time, finding mixed evidence but suggesting caution, especially with red meat.
- Liver and Kidney Health
Long Term Effects Of High Protein Diets On Renal Function
Research shows that long-term high-protein diets may harm kidney function, especially from red meat, though the evidence is mixed and more studies are needed.
- Nutrition and Health
Long Term Effects Of Isocaloric Vs LCD
Both very low-carb and low-fat diets led to similar weight loss over one year, but the low-carb diet improved triglycerides and HDL while raising LDL cholesterol.
- Joint, Muscle Health and Exercise
Long Term Leucine Supplementation Does Not Increas 2009 The American Journal
A three-month study found that taking leucine supplements with meals did not increase muscle mass or strength in healthy elderly men.
- Joint, Muscle Health and Exercise
Long Term Leucine Supplementation Does Not Increas 2009 The American Journal(1)
Taking leucine supplements daily for three months did not increase muscle mass or strength in healthy older men.
- Heart Health
Long Term Low Calorie Low Protein Vegan Diet And Endurance Exercise Are Associated With Low Cardiometabolic Risk
A long-term low-calorie vegan diet and regular endurance exercise both significantly reduce heart disease risk factors compared to a typical Western diet.
- Hormone Health
Long Term Persistence Of Hormonal Adaptations To Weight Loss
After people lose weight, their hunger hormones remain altered for at least a year, making their bodies fight to regain the lost weight.
- Hormone Health
Long Term Successful Weight Loss With A Combination Biphasic Ketogenic Mediterranean Diet And Mediterranean Diet Maintenance Protocol
A combination approach using short periods of ketogenic Mediterranean diet followed by regular Mediterranean eating helped 88% of obese participants lose significant weight and keep it off for a year.
- Gut Health
Long Term Yogurt Intake And Colorectal Cancer Incidence Subclassified By Bifidobacterium Abundance In Tumor
Researchers found that eating yogurt regularly may help protect against colorectal cancer, particularly when beneficial gut bacteria called Bifidobacterium are present in higher amounts.
- Environment and Health
Longer Wavelengths In Sunlight Pass Through The Human Body And Have A Systemic Impact Which Improves Vision
Researchers found that longer wavelengths of sunlight can pass through the human body and improve vision by boosting cellular energy production, even when the light doesn't directly reach the eyes.
- Brain and Nerve Health
Longitudinal Association Between Fasting Blood Glucose C 2017 The American J
Higher fasting blood sugar levels significantly increased stroke risk in people with high blood pressure, but folic acid supplements helped reduce this risk.
- Nutrition and Health
Longitudinal Metabolomic Profiling Of Amino Acids And Lipids Across Healthy Pregnancy
Researchers tracked blood chemistry changes throughout healthy pregnancies, finding that the body shifts how it processes proteins and fats to support growing babies.
- Environment and Health
Losing Sleep By Staying Up Late Leads Adolescents To Consume More Carbohydrates And A Higher Glycemic Load
A study found that when teenagers don't get enough sleep, they eat more carbohydrates, sugary foods, and high blood sugar-spiking foods while eating fewer fruits and vegetables.
- Liver and Kidney Health
Loss Of ABHD5 Promotes The Aggressiveness Of Prostate Cancer Cells
Researchers found that aggressive prostate cancer cells have lower levels of a protein called ABHD5 that normally helps break down stored fats for energy.
Disclaimer: this library, including every summary, is for general informational and educational purposes only. It does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider before changing your diet, exercise, or health regimen, or if you have questions about a medical condition.